Skip to main content
SpringerLink
Log in

Adipose-Derived Regenerative Cells

  • Chapter
  • First Online:
Stem Cells in Aesthetic Procedures

  • 1750 Accesses

Abstract

Regenerative tissue engineering utilizing autologous adult stem cells is rapidly emerging as a viable means of restoring tissue and organ function. Adipose-derived stem and regenerative cells (ADRCs) or adipose-derived stem cells (ASCs) are valuable in fat graft survival and repair and regeneration of damaged tissue or organs (Donofrio, Dermatol Surg 26:1129–1134, 2000; Gimble and Guilak, Cytotherapy 5:362–365, 2003). Fat harvesting by means of minimally invasive liposuction techniques results in minimal morbidity and significantly higher stem cell yields as compared to bone marrow. The author discusses ASC harvesting and processing as well as the mechanisms of regenerative capacity.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Butler DL. Functional tissue engineering: the role of biomechanics. J Biomech Eng. 2000;122(6):570–5.

    Article  CAS  PubMed  Google Scholar 

  2. Gimble JM. Adipose tissue-derived therapeutics. Expert Opin Biol Ther. 2003;3(5):705–13.

    Article  CAS  PubMed  Google Scholar 

  3. Donofrio LM. Structural autologous lipoaugmentation: a pan-facial technique. Dermatol Surg. 2000;26(12):1129–34.

    Article  CAS  PubMed  Google Scholar 

  4. Gimble J, Guilak F. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy. 2003;5(5):362–9.

    Article  PubMed  Google Scholar 

  5. Strem BM, Hedrick MH. The growing importance of fat in regenerative medicine. Trends Biotechnol. 2004;23(2):64–6.

    Article  Google Scholar 

  6. Strem BM. Adipose tissue derived-stem cells enhance cardiac function following surgically induced myocardial infarction. Dallas: AHA Scientific Sessions; 2005.

    Google Scholar 

  7. Rehman J, Traktuev D, Li J, Merfeld-Clauss S, Temm-Grove CJ, Bovenkerk JE, Pell CL, Johnstone BH, Considine RV, March KL. Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells. Circulation. 2004;109(10):1292–8.

    Article  PubMed  Google Scholar 

  8. Van RL, Bayliss CE, Roncari DA. Cytological and enzymological characterization of adult human adipocyte precursors in culture. J Clin Invest. 1976;58(3):699–704.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  9. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 2001;7(2):211–28.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Innovative Cosmetic Surgery Center, 7425 E Shea Blvd, Suite 107, Scottsdale, AZ, 85260, USA

    Todd Malan M.D.

Authors
  1. Todd Malan M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Todd Malan M.D. .

Editor information

Editors and Affiliations

  1. Section of Surgery, Newport Specialty Hospital, Tustin, California, USA

    Melvin A. Shiffman

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Ancona, Italy

    Alberto Di Giuseppe

  3. Department of Plastic Surgery, University of Padova, Padova, Italy

    Franco Bassetto

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Malan, T. (2014). Adipose-Derived Regenerative Cells. In: Shiffman, M., Di Giuseppe, A., Bassetto, F. (eds) Stem Cells in Aesthetic Procedures. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45207-9_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-45207-9_20

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45206-2

  • Online ISBN: 978-3-642-45207-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation