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Viruses and the Lung pp 87–93Cite as

Parainfluenza Virus

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Abstract

Name of Virus: Parainfluenza virus

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References

  • Akizuki S, Nasu N, Setoguchi M et al (1991) Parainfluenza virus pneumonitis in an adult. Arch Pathol Lab Med 115:824–826

    CAS  PubMed  Google Scholar 

  • Bellau-Pujol S, Vabret A, Legrand L et al (2005) Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses. J Virol Methods 126:53–63

    Article  CAS  PubMed  Google Scholar 

  • Belshe RB, Hissom FK (1982) Cold adaptation of parainfluenza virus type 3: induction of three phenotypic markers. J Med Virol 10:235–242

    Article  CAS  PubMed  Google Scholar 

  • Blau DM, Compans RW (1997) Adaptation of measles virus to polarized epithelial cells: alterations in virus entry and release. Virology 231:281–289

    Article  CAS  PubMed  Google Scholar 

  • Bose S, Welch BD, Kors CA et al (2011) Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. J Virol 85:12855–12866

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chan KH, Peiris JSM, Lim W et al (2008) Comparison of nasopharyngeal flocked swabs and aspirates for rapid diagnosis of respiratory viruses in children. J Clin Virol 42:65–69

    Article  CAS  PubMed  Google Scholar 

  • Chanock RM (1956) Association of a new type of cytopathogenic myxovirus with infantile croup. J Exp Med 104:555–576

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chin J, Magoffin RL, Shearer LA et al (1969) Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population. Am J Epidemiol 89:449–463

    CAS  PubMed  Google Scholar 

  • Choppin PW (1964) Multiplication of a myxovirus (SV5) with minimal cytopathic effects and without interference. Virology 23:224–233

    Article  CAS  PubMed  Google Scholar 

  • Coiras MT, Aguilar JC, García ML et al (2004) Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays. J Med Virol 72:484–495

    Article  CAS  PubMed  Google Scholar 

  • Crookshanks FK, Belshe RB (1984) Evaluation of cold-adapted and temperature-sensitive mutants of parainfluenza virus type 3 in weanling hamsters. J Med Virol 13:243–249

    Article  CAS  PubMed  Google Scholar 

  • Denny FW Jr (1995) The clinical impact of human respiratory virus infections. Am J Respir Crit Care Med 152:S4–S12

    Article  PubMed  Google Scholar 

  • Dobrovoljac M, Geelhoed GC (2012) How fast does oral dexamethasone work in mild to moderately severe croup? A randomized double-blinded clinical trial. Emerg Med Australas 24:79–85

    Article  PubMed  Google Scholar 

  • Echevarría JE, Erdman DD, Swierkosz EM et al (1998) Simultaneous detection and identification of human parainfluenza viruses 1, 2, and 3 from clinical samples by multiplex PCR. J Clin Microbiol 36:1388–1391

    PubMed  PubMed Central  Google Scholar 

  • Eugene-Ruellan G, Freymuth F, Bahloul C et al (1998) Detection of respiratory syncytial virus A and B and parainfluenzavirus 3 sequences in respiratory tracts of infants by a single PCR with primers targeted to the L-polymerase gene and differential hybridization. J Clin Microbiol 36:796–801

    CAS  PubMed  PubMed Central  Google Scholar 

  • Fan J, Henrickson KJ (1996) Rapid diagnosis of human parainfluenza virus type 1 infection by quantitative reverse transcription-PCR-enzyme hybridization assay. J Clin Microbiol 34:1914–1917

    CAS  PubMed  PubMed Central  Google Scholar 

  • Frayha H, Castriciano S, Mahony J et al (1989) Nasopharyngeal swabs and nasopharyngeal aspirates equally effective for the diagnosis of viral respiratory disease in hospitalized children. J Clin Microbiol 27:1387–1389

    CAS  PubMed  PubMed Central  Google Scholar 

  • Fuentes SM, Sun D, Schmitt AP et al (2010) Phosphorylation of paramyxovirus phosphoprotein and its role in viral gene expression. Future Microbiol 5:9–13

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Geelhoed GC (2005) Budesonide offers no advantage when added to oral dexamethasone in the treatment of croup. Pediatr Emerg Care 21:359–362

    Article  PubMed  Google Scholar 

  • Glezen WP, Frank AL, Taber LH et al (1984) Parainfluenza virus type 3: seasonality and risk of infection and reinfection in young children. J Infect Dis 150:851–857

    Article  CAS  PubMed  Google Scholar 

  • Griffin MR, Walker FJ, Iwane MK et al (2004) Epidemiology of respiratory infections in young children: insights from the new vaccine surveillance network. Pediatr Infect Dis J 23:S188–S192

    Article  PubMed  Google Scholar 

  • Hall CB (2001) Respiratory syncytial virus and parainfluenza virus. N Engl J Med 344:1917–1928

    Article  CAS  PubMed  Google Scholar 

  • Halonen P, Meurman O, Lövgren T et al (1983) Detection of viral antigens by time-resolved fluoroimmunoassay. Curr Top Microbiol Immunol 104:133–146

    CAS  PubMed  Google Scholar 

  • Hammitt LL, Kazungu S, Welch S et al (2011) Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection. J Clin Microbiol 49:2318–2320

    Article  PubMed  PubMed Central  Google Scholar 

  • Henderson FW (1987) Pulmonary infections with respiratory syncytial virus and the parainfluenza viruses. Semin Respir Infect 2:112–121

    CAS  PubMed  Google Scholar 

  • Henrickson KJ (1994) Lower respiratory viral infections in immunocompetent children. Adv Pediatr Infect Dis 9:59–96

    CAS  PubMed  Google Scholar 

  • Henrickson KJ (2003) Parainfluenza viruses. Clin Microbiol Rev 16:242–264

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Henrickson KJ, Savatski LL (1997) Antigenic structure, function, and evolution of the hemagglutinin-neuraminidase protein of human parainfluenza virus type 1. J Infect Dis 176:867–875

    Article  CAS  PubMed  Google Scholar 

  • Henrickson KJ, Kuhn SM, Savatski LL (1994) Epidemiology and cost of infection with human parainfluenza virus types 1 and 2 in young children. Clin Infect Dis 18:770–779

    Article  CAS  PubMed  Google Scholar 

  • Hierholzer JC, Bingham PG, Coombs RA et al (1989) Comparison of monoclonal antibody time-resolved fluoroimmunoassay with monoclonal antibody capture-biotinylated detector enzyme immunoassay for respiratory syncytial virus and parainfluenza virus antigen detection. J Clin Microbiol 27:1243–1249

    CAS  PubMed  PubMed Central  Google Scholar 

  • Karron RA, Wright PF, Hall SL et al (1995) A live attenuated bovine parainfluenza virus type 3 vaccine is safe, infectious, immunogenic, and phenotypically stable in infants and children. J Infect Dis 171:1107–1114

    Article  CAS  PubMed  Google Scholar 

  • Komada H, Kusagawa S, Orvell C et al (1992) Antigenic diversity of human parainfluenza virus type 1 isolates and their immunological relationship with Sendai virus revealed by using monoclonal antibodies. J Gen Virol 73(Pt 4):875–884

    Article  CAS  PubMed  Google Scholar 

  • Laurichesse H, Dedman D, Watson JM et al (1999) Epidemiological features of parainfluenza virus infections: laboratory surveillance in England and Wales, 1975–1997. Eur J Epidemiol 15:475–484

    Article  CAS  PubMed  Google Scholar 

  • Lee M-S, Walker RE, Mendelman PM (2005) Medical burden of respiratory syncytial virus and parainfluenza virus type 3 infection among US children. Implications for design of vaccine trials. Hum Vaccin 1:6–11

    PubMed  Google Scholar 

  • Leung AKC, Kellner JD, Johnson DW (2004) Viral croup: a current perspective. J Pediatr Health Care 18:297–301

    PubMed  Google Scholar 

  • Massion PP, Funari CC, Ueki I et al (1993) Parainfluenza (Sendai) virus infects ciliated cells and secretory cells but not basal cells of rat tracheal epithelium. Am J Respir Cell Mol Biol 9:361–370

    Article  CAS  PubMed  Google Scholar 

  • Osiowy C (1998) Direct detection of respiratory syncytial virus, parainfluenza virus, and adenovirus in clinical respiratory specimens by a multiplex reverse transcription-PCR assay. J Clin Microbiol 36:3149–3154

    CAS  PubMed  PubMed Central  Google Scholar 

  • Peltola V, Heikkinen T, Ruuskanen O (2002) Clinical courses of croup caused by influenza and parainfluenza viruses. Pediatr Infect Dis J 21:76–78

    Article  PubMed  Google Scholar 

  • Piralla A, Percivalle E, Di Cesare-Merlone A et al (2009) Multicluster nosocomial outbreak of parainfluenza virus type 3 infection in a pediatric oncohematology unit: a phylogenetic study. Haematologica 94:833–839

    Article  PubMed  Google Scholar 

  • Reed G, Jewett PH, Thompson J et al (1997) Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children <5 years old. J Infect Dis 175:807–813

    Article  CAS  PubMed  Google Scholar 

  • Sarkkinen HK, Halonen PE, Arstila PP et al (1981) Detection of respiratory syncytial, parainfluenza type 2, and adenovirus antigens by radioimmunoassay and enzyme immunoassay on nasopharyngeal specimens from children with acute respiratory disease. J Clin Microbiol 13:258–265

    CAS  PubMed  PubMed Central  Google Scholar 

  • Schmidt AC, McAuliffe JM, Murphy BR et al (2001) Recombinant bovine/human parainfluenza virus type 3 (B/HPIV3) expressing the respiratory syncytial virus (RSV) G and F proteins can be used to achieve simultaneous mucosal immunization against RSV and HPIV3. J Virol 75:4594–4603

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Schmidt AC, Schaap-Nutt A, Bartlett EJ et al (2011) Progress in the development of human parainfluenza virus vaccines. Expert Rev Respir Med 5:515–526

    Article  PubMed  PubMed Central  Google Scholar 

  • South M, Williams K (2012) Evidence to support current use of nebulised epinephrine in croup to achieve immediate clinical improvement. J Paediatr Child Health 48:279–280

    Article  PubMed  Google Scholar 

  • Weinberg GA, Hall CB, Iwane MK et al (2009) Parainfluenza virus infection of young children: estimates of the population-based burden of hospitalization. J Pediatr 154:694–699

    Article  PubMed  Google Scholar 

  • Wendt CH, Hertz MI (1995) Respiratory syncytial virus and parainfluenza virus infections in the immunocompromised host. Semin Respir Infect 10:224–231

    CAS  PubMed  Google Scholar 

  • Yao Q, Hu X, Compans RW (1997) Association of the parainfluenza virus fusion and hemagglutinin-neuraminidase glycoproteins on cell surfaces. J Virol 71:650–656

    CAS  PubMed  PubMed Central  Google Scholar 

  • Zhang L, Collins PL, Lamb RA et al (2011) Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology 421:67–77

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pathology, William Beaumont Hospital – Troy Campus, Oakland University William Beaumont School of Medicine, 44201 Dequindre Road, Troy, MI, 48085, USA

    Said H. Khayyata M.D.

  2. Department of Anatomic Pathology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA

    Carol Farver M.D.

Authors
  1. Said H. Khayyata M.D.
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  2. Carol Farver M.D.
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Corresponding author

Correspondence to Carol Farver M.D. .

Editor information

Editors and Affiliations

  1. Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA

    Armando E. Fraire

  2. Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA

    Bruce A. Woda

  3. Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA

    Raymond M. Welsh

  4. Massachusetts General Hospital, Boston, Massachusetts, USA

    Richard L. Kradin

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Khayyata, S.H., Farver, C. (2014). Parainfluenza Virus. In: Fraire, A., Woda, B., Welsh, R., Kradin, R. (eds) Viruses and the Lung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40605-8_10

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  • DOI: https://doi.org/10.1007/978-3-642-40605-8_10

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  • Print ISBN: 978-3-642-40604-1

  • Online ISBN: 978-3-642-40605-8

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