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Incidence, Risk Factors, and Outcome

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Book cover Managing Renal Injury in the Elderly Patient

Abstract

Acute kidney injury (AKI) is largely a disease of older patients. Age-related changes in the kidney as well as the accumulated comorbid conditions and polypharmacy associated with aging greatly increase the susceptibility for the development of AKI. While the etiologies of AKI in older patients encompass the same spectrum of prerenal, intrarenal, and postrenal causes that are seen in other age groups, older patients tend to have a higher relative risk for developing AKI from specific causes such as obstructive uropathy. The elderly patient poses special challenges as this group of patients generally has poorer short- and long-term outcomes than younger patients. These poor outcomes necessarily influence decision making on whether to provide aggressive care such as offering continuous renal replacement therapy when faced with older patients with AKI and multisystem organ failure. This chapter focuses on the epidemiological issues in AKI for older patients as well as some critical outcome data.

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Author information

Authors and Affiliations

  1. Department of Nephrology, University of Virginia, 1545 Running Cedar, Charlottesville, VA, 222911, USA

    Mitchell H. Rosner MD

  2. Department of Nephrology Dialysis and Transplantation, St. Bortolo Hospital and International Renal Research Institute of Vicenza (IRRIV), Viale Rodolfi 37, Vicenza, 36100, Italy

    Claudio Ronco MD

  3. Division of Nephrology-Hypertension, University of California, San Diego, 200 West Arbor Drive #8409, San Diego, CA, 92103-8409, USA

    Dinna N. Cruz MD, MPH

Authors
  1. Mitchell H. Rosner MD
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  2. Claudio Ronco MD
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  3. Dinna N. Cruz MD, MPH
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Corresponding author

Correspondence to Dinna N. Cruz MD, MPH .

Editor information

Editors and Affiliations

  1. Dep. of Nephrology and Hypertension, Otto von Guericke University Magdeburg, Magdeburg, Germany

    Michael Haase

  2. Dep. of Nephrology and Hypertension, Otto von Guericke University Magdeburg, Magdeburg, Germany

    Anja Haase-Fielitz

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Rosner, M.H., Ronco, C., Cruz, D.N. (2014). Incidence, Risk Factors, and Outcome. In: Haase, M., Haase-Fielitz, A. (eds) Managing Renal Injury in the Elderly Patient. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39947-3_2

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  • DOI: https://doi.org/10.1007/978-3-642-39947-3_2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39946-6

  • Online ISBN: 978-3-642-39947-3

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