Abstract
We present a software solution for planning and simulating radio-frequency ablation (RFA) treatment for patients suffering from hepatocellular carcinoma. Our software provides the graphical front-end for the results of the EU FP7 project IMPPACT. The main planning application was designed to assist with the identification of minimum-risk setups for RFA probes and generation of evaluable 3D representations of the predicted necrosis zones. Patient-specific mesh data describing the involved anatomic structures are used to individually parameterize the simulation procedure for personalized results. Our software supplies tools for extracting the required anatomic meshes from computed tomography (CT) images and for specifying custom intervention protocols. Data collected during simulations allow for detailed illustration of expected effectiveness and progress of heat-induced necrosis over time. Our software was evaluated positively by medical personnel and has been successfully put into practice at two independent European clinical sites.
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References
Alhonnoro, T., Pollari, M., Lilja, M., Flanagan, R., Kainz, B., Muehl, J., Mayrhauser, U., Portugaller, H.: Vessel segmentation for ablation treatment planning and simulation. In: Händler, W., Spies, P.P. (eds.) Rechnerstrukturen und Betriebsprogrammierung. LNCS, vol. 13, pp. 45–52. Springer, Heidelberg (1974)
Carr, B.I.: Hepatocellular carcinoma: Current management and future trends. Gastroenterology 127, 218–224 (2004)
Lau, W.Y., Lai, E.C.: The Current Role of Radiofrequency in the Management of Hepatocellular Carcinoma: a Systematic Review. Annals of Surgery 249(1), 20–25 (2009)
O’Neill, D.P., Peng, T., Payne, S.J.: A two-equation coupled system model for determination of liver tissue temperature during radio frequency ablation. In: Proc. IEEE Engineering in Medicine and Biology vol. 2009, pp. 3893–3896 (2009)
Pennes, H.H.: Analysis of tissue and arterial blood temperatures in the resting human forearm. Journal of Applied Physiology 1(2), 93–122 (1948)
Pricher, A., Medinger, M., Drevs, J.: Liver cancer: Targeted future options. World Journal of Hepatology 3(2), 38–44 (2011)
Rieder, C., Altrogge, I., Kröger, T., Zidowitz, S., Preusser, T.: Interactive Approximation of the Ablation Zone incorporating Heatsink Effects for Radiofrequency Ablation. In: Proc. of CURAC, pp. 9–12 (2010)
Rieder, C., Schwier, M., Weihusen, A., Zidowitz, S., Peitgen, H.O.: Visualization of risk structures for interactive planning of image guided radiofrequency ablation of liver tumors. In: Proc. SPIE Medical Imaging, vol. 7261, pp. 726134-1–726134-9 (2009)
Rieder, C., Weihusen, A., Schumann, C., Zidowitz, S., Peitgen, H.: Visual support for interactive post-interventional assessment of radiofrequency ablation therapy. Computer Graphics Forum 29, 1093–1102 (2010)
Schumann, C., Rieder, C., Bieberstein, J., Weihusen, A., Zidowitz, S., Moltz, J.H., Preusser, T.: State of the art in computer-assisted planning, intervention and assessment of liver-tumor ablation. Critical Reviews in Biomedical Engineering 38(1), 31–52 (2009)
Tungjitkusolmun, S., Staelin, S.T., Haemmerich, D., Tsai, J.Z., Webster, J.G., Lee Jr., F.T., Mahvi, D.M., Vorperian, V.R.: Three-dimensional finite-element analyses for radio-frequency hepatic tumor ablation. IEEE Transactions on Biomedical Engineering 49(1), 3–9 (2002)
Villard, C., Soler, L., Papier, N., Agnus, V., Thery, S., Gangi, A., Mutter, D., Marescaux, J.: Virtual radiofrequency ablation of liver tumors. In: Ayache, N., Delingette, H. (eds.) IS4TM 2003. LNCS, vol. 2673, pp. 366–374. Springer, Heidelberg (2003)
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Kerbl, B. et al. (2013). Intervention Planning of Hepatocellular Carcinoma Radio-Frequency Ablations. In: Drechsler, K., et al. Clinical Image-Based Procedures. From Planning to Intervention. CLIP 2012. Lecture Notes in Computer Science, vol 7761. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38079-2_2
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DOI: https://doi.org/10.1007/978-3-642-38079-2_2
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