Abstract
In old patients metastases are by far the most frequent lesion. Their detection must be planned carefully and only when the knowledge that is obtained will have therapeutic consequences. Bone scintigraphy, radiographs, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) all have specific uses and indications. The treatment of some primary bone tumors has been completely transformed by chemotherapy but mainly in young patients. At the same time, surgery has changed and drastic measures, such as amputation, are much rarer. The perfect local staging allows the best choice of indications as well as evaluation of neoadjuvant treatment. Plain film remains the first indispensable diagnostic step, especially for primary tumors. CT improves diagnostic capability, and MRI is the best technique for local staging. PET can evaluate new criteria, but it is still being evaluated.
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- CT:
-
Computed tomography
- MRI:
-
Magnetic resonance imaging
- PET:
-
Positron emission tomography
- STIR:
-
Short tau inversion recovery
References
Abrams HL, Spiro R, Goldstein N (1950) Metastases in carcinoma. Analysis of 1000 autopsied cases. Cancer 2:74–85
Aisen AM, Martel W, Braunstein EM, McMilin KI, Philips WA, Kling TF (1986) MRI and CT evaluation of primary bone and soft tissue tumors. AJR Am J Roentgenol 146:749–756
Algra PR, Bloem JL, Tissing H et al (1991) Detection of vertebral metastases: comparison between MR imaging and bone scintigraphy. Radiographics 11:219–232
Baur A, Stabler A, Bruning R et al (1998) Diffusion-weighted MR imaging of bone marrow: differentiation of benign versus pathologic compression fractures. Radiology 207:349–356
Baur A, Stäbler A, Nagel D, Lamerz R, Bartl R, Hiller E, Wendtner C, Bachner F, Reiser M (2002a) Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon? Cancer 95(6):1334–1345
Baur A, Dietrich O, Reiser M (2002b) Diffusion-weighted imaging of the spinal column. Neuroimaging Clin N Am 12(1):147–160
Bloem JL, Taminiau AHM, Eulderink F, Hermans J, Pauwels EKJ (1988) Radiologic staging of primary bone sarcoma. MRI, scintigraphy, angiography and CT correlated with pathologic examination. Radiology 169:805–810
Boccardo F, Bruzzi P, Cionini L et al (1995) Appropriateness of the use of clinical and radiologic examinations and laboratory tests in the follow-up of surgically-treated breast cancer patients. Results of the Working Group on the Clinical Aspects of Follow-up. Ann Oncol 6(Suppl 2):57–59
Bohndorf K, Reiser M, Lochner B, Feaux de Lacroux W, Steinbrich W (1986) Magnetic resonance imaging of primary tumors and tumor like lesions of bone. Skeletal Radiol 15:511–517
Brown KT, Kattapuram SSV, Rosentahl DI (1986) Computed tomography analysis of bone tumors: patterns of cortical destruction and soft tissue extension. Skeletal Radiol 15:448–451
De Baere T, Vanel D, Shapeero LG, Charpentier A, Terrier P, Di Paola M (1992) Osteosarcoma after chemotherapy: evaluation with contrast material-enhanced subtraction MR imaging. Radiology 185:587–592
Deutsch A, Resnick D (1980) Eccentric cortical metastases to the skeleton from bronchogenic carcinoma. Radiology 137:49–52
Eustace S, Tello R, DeCarvalho V et al (1997) A comparison of whole-body turbo STIR MR imaging and planar 99mTc-methylene diphosphonate scintigraphy in the examination of patients with suspected skeletal metastases. Am J Roentgenol 169:1655–1661
Fragiadakis EG, Panayotopoulous G (1972) Metastatic carcinoma of the hand. Hand 4:268
Geirnaerdt MJ, Hogendoorn PC, Bloem JL, Taminiau AH, van der Woude HJ (2000) Cartilaginous tumors: fast contrast-enhanced MR imaging. Radiology 214(2):539–546
Glass RB, Poznanski AK, Fisher MR, Shkolnik A, Dias L (1986) MR imaging of osteoid osteoma. J Comput Assist Tomogr 10:1065–1067
Kattapuram SV, Khurana JS, Scott JA et al (1990) Negative scintigraphy with positive magnetic resonance imaging in bone metastases. Skeletal Radiol 19:113–116
Kenney PJ, Gilula LA, Murphy WA (1981) The use of CT to distinguish osteochondroma and chondrosarcoma. Radiology 138:129–137
Krishnamurthy GT, Tubis M, Hiss J et al (1977) Distribution pattern of metastatic bone disease. A need for total body skeletal image. JAMA 237:2504–2506
Laredo JD, Lakhdari K, Bellaiche L et al (1995) Acute vertebral collapse: CT findings in benign and malignant non-traumatic cases. Radiology 194:41–48
Lauenstein TC, Freudenberg LS, Goehde SC et al (2002) Whole-body MRI using a rolling table platform for the detection of bone metastases. Eur Radiol 12:2091–2099
Lecouvet FE, Vande Berg BC, Malghem J, Maldague BE (2001) Magnetic resonance and computed tomography imaging in multiple myeloma. Semin Musculoskelet Radiol 5(1):43–55, Review
Lodwick GS, Wilson AJ, Farrel C, Virtama P, Smeltzer FM, Ditrich F (1980) Estimating rate of growth in bone lesions: observer performance and error. Radiology 134:585–590
Madewell JE, Ragsdale BD, Sweet DE (1981) Radiology and pathology analysis of solitary bone lesions. Radiol Clin North Am 19:715–748
Murphey MD, Flemming DJ, Boyea SR, Bojescul JA, Sweet DE, Temple HT (1998) Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. Radiographics 18(5):1213–1237; quiz 1244–1245
Picci P, Vanel D, Briccoli A, Talle K, Haakenaasen U, Malaguti C, Monti C, Ferrari C, Bacci G, Saeter G, Alvegard TA (2001) Computed tomography of pulmonary metastases from osteosarcoma: the less poor technique. A study of 51 patients with histological correlation. Ann Oncol 12(11):1601–1604
Regent D, Tamisier JN, Fery A, Bernard C, Delagoutte JP, Pourel JP, Gaucher A (1986) Intérêt du traitement de l’information dans l’exploration scanographique des lésions focales bénignes de l’os. Rev Rhum Mal Osteoartic 53:77–82
Rosselli Del Turco M, Palli D, Cariddi A, Ciatto S, Pacini P, Distante V (1994) Intensive diagnostic follow-up after treatment of primary breast cancer. A randomized trial National Research Council Project on Breast Cancer follow-up. JAMA 271:1593–1597
Schima W, Amann G, Stiglbauer R et al (1994) Preoperative staging of osteosarcoma: efficacy of MR imaging in detecting joint involvement. AJR Am J Roentgenol 163:1171–1175
Shaylor PJ, Peake D, Grimer RJ, Carter SR, Tillman RM, Spooner D (1999) Paget’s osteosarcoma – no cure in sight. Sarcoma 3(3–4):191–192
Silverberg E, Lubera J (1987) Cancer statistics, 1987. CA Cancer J Clin 37:2–19
Staals EL, Bacchini P, Bertoni F (2006) Dedifferentiated central chondrosarcoma. Cancer 106(12):2682–2691
Staals EL, Bacchini P, Mercuri M, Bertoni F (2007) Dedifferentiated chondrosarcomas arising in preexisting osteochondromas. J Bone Joint Surg Am 89(5):987–993
Traill ZC, Talbot D, Golding S et al (1999) Magnetic resonance imaging versus radionuclide scintigraphy in screening for bone metastases. Clin Radiol 54:448–451
van der Woude HJ, Bloem JL, Holscher HC, Nooy MA, Taminiau AH, Hermans J, Falke TH, Hogendoorn PC (1994) Monitoring the effect of chemotherapy in Ewing’s sarcoma of bone with MR imaging. Skeletal Radiol 23(7):493–500
Vanel D, Henri-Amar M, Lumbroso J, Lemalet E, Couanet D, Piekarski JD, Masselot J, Boddaert A, Kalifa C, Le Chevalier T, Lemoine G (1984) Pulmonary evaluation of patients with osteosarcoma: roles of standard radiography, tomography, CT, scintigraphy and tomoscintigraphy. AJR Am J Roentgenol 143:519–523
Vanel D, Bittoun J, Tardivon A (1998) MRI of bone metastases. Eur Radiol 8:1345–1351
Vanel D, Kreshak J, Larousserie F, Alberghini M, Mirra J, De Paolis M, Picci P (2012) Enchondroma vs. chondrosarcoma: a simple, easy-to-use, new magnetic resonance sign. Eur J Radiol [Epub ahead of print]
Verstraete KL, De Deene Y, Roels H et al (1994) Benign and malignant musculoskeletal lesions: dynamic contrast-enhanced MR imaging parametric “first-pass” images depict tissue vascularization and perfusion. Radiology 192:835–843
Wyche LD, De Santos LA (1978) Spiculated periosteal reaction in metastatic disease resembling osteosarcoma. Orthopedics 1:215
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Vanel, D., Picci, P., Ridereau-Zins, C., Gambarotti, M. (2013). Bone Tumors. In: Guglielmi, G., Peh, W., Guermazi, A. (eds) Geriatric Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35579-0_8
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