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Literature Review: Cardiovascular Disorders and Lipid Profile

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Minerals and Lipids Profiles in Cardiovascular Disorders in South Asia

Abstract

Gururajan et al. (2010) determined that elevated lipid profile and reduced antioxidants accelerate the formation of atherosclerosis. Multiple lines of evidences have suggested that increased lipids and low antioxidants are the major risk factors for the incidence of acute coronary syndrome. Oxidative stress evaluation is now considered as an index for the assessment of development of CAD. Total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides were analyzed along with nonenzymatic antioxidants such as vitamin C, vitamin E, reduced glutathione, MDA, and protein thiol in controls and patients with ACS. The levels of total cholesterol and LDL cholesterol were significantly raised in patients when compared to controls in contrast to lowering of HDL-cholesterol levels in patients than controls. Vitamin C, vitamin E, reduced glutathione, MDA, and protein thiol levels were significantly lowered in patients than controls (p < 0.05).Oxidative stress and lipid profile should be included as important markers in the early detection of acute coronary syndrome.

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References

  • American Heart Association (AHA) (2003) Heart disease and stroke statistics: 2004 update. American Heart Association, Dallas, TX

    Google Scholar 

  • Ballantyne CM (1998) Low-density lipoproteins and risk for coronary artery disease. Am J Cardiol 82:3Q–12Q

    Article  CAS  Google Scholar 

  • Beckles GL, Miller GJ, Kirkwood BR, Alexis SD, Carson DC (1986) High total and cardiovascular disease mortality in adults of Indian descent in Trinidad, unexplained by major coronary risk factors. Lancet 1:1298–1301

    Article  CAS  Google Scholar 

  • Bermudez OI, Velez-Carrasco W, Schaefer EJ, Tucker KL (2002) Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes. Am J Clin Nutr 76(6):1214–1221

    CAS  Google Scholar 

  • Burman A, Jain K, Gulati R, Chopra V, Agrawal DP, Vaisisht S (2004) Lipoprotein (a) as a marker of coronary artery disease and its association with dietary fat. J Assoc Physicians India 52:99–102

    Google Scholar 

  • Ellison RC, Zhang Y, Qureshi MM, Knox S, Arnett DK, Province MA, Investigators of the NHLBI Family Heart Study (2004) Lifestyle determinants of high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study. Am Heart J 147:529–535

    Article  CAS  Google Scholar 

  • Enas EA, Garg A, Davidson MA (1996) Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America. Indian Heart J 48:343–352

    CAS  Google Scholar 

  • Gaziano JM, Sesso HD, Breslow JL (1999) Relation between systemic hypertension and blood lipids on the risk of myocardial infarction. Am J Cardiol 84:768–773

    Article  CAS  Google Scholar 

  • Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD (1989) High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation 79:8–15

    Google Scholar 

  • Gould AL, Rossouw JE, Santanello NC, Heyse JF, Furberg CD (1998) Cholesterol reduction yields clinical benefit: impact of statin trials. Circulation 97:946–952

    Article  CAS  Google Scholar 

  • Gururajan P, Gurumurthy P, Nayar P, Chockalingam M, Bhuvaneshwari S, Babu S, Sarasabharati A, Victor D, Cherian KM (2010) Lipid profile and non-enzymic antioxidant status in patients with acute coronary syndrome in South India. Heart Lung Circ 19(2):75–80

    Article  CAS  Google Scholar 

  • Habib SS (2006) Frequency distribution of atherogenic dyslipidemia in Saudi type 2 diabetic patients. Pak J Physiol 2:20–23

    Google Scholar 

  • Haffner SM, American Diabetes Association (2004) Dyslipidemia management in adults with diabetes. Diabetes Care 27:S68–S71

    Article  Google Scholar 

  • Haffner SM, Miettinen H, Gaskill SP, Stern MP (1996) Metabolic precursors of hypertension: the San Antonio Heart Study. Arch Intern Med 156:1994–2000

    Article  CAS  Google Scholar 

  • Hokanson JE, Austin MA (1996) Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies. J Cardiovasc Risk 3:213–219

    Article  CAS  Google Scholar 

  • Hong MK, Romm PA, Reagan K, Green CE, Rackley CE (1992) Effects of oestrogen replacement therapy on serum lipid values and angiographically defined coronary artery disease in postmenopausal women. Am J Cardiol 69:176–178

    Article  CAS  Google Scholar 

  • Idemudia JO, Ugwuja EI (2009) Plasma lipid profiles in hypertensive Nigerians. Internet J Cardiovasc Res 6(2):8

    Google Scholar 

  • Iqbal MP, Shafiq M, Mehboobali N, Iqbal SP, Abbasi K (2004) Variability in lipid profile in patients with acute myocardial infarction from two tertiary care hospitals in Pakistan. J Pak Med Assoc 54(11):544–549

    CAS  Google Scholar 

  • Johnson ML, Pietz K, Battleman DS, Beyth RJ (2004) Prevalence of comorbid hypertension and dyslipidemia and associated cardiovascular disease. Am J Manag Care 10:926–932

    Google Scholar 

  • Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) (1997) The sixth reports of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI). Arch Intern Med 157:2413–2446

    Article  Google Scholar 

  • Kanaley JA, Sames C, Swisher L, Swick AG, Steppan CM, Feiglin D, Jaynes EB, Meyer RA, Weinstock RS (2001) Abdominal fat distribution in pre and post menopausal women. The impact of physical activity, age and menopausal status. Metabolism 50(8):976–982

    Article  CAS  Google Scholar 

  • Karthikeyan G, Teo KK, Islam S, McQueen MJ, Pais P, Wang X, Sato H, Lang CC, Sitthi-Amorn C, Pandey MR, Kazmi K, Sanderson JE, Yusuf S (2009) Lipid profile, plasma apolipoproteins, and risk of a first myocardial infarction among Asians: an analysis from the INTERHEART Study. J Am Coll Cardiol 53(3):244–253

    Article  CAS  Google Scholar 

  • Khoo KL, Tan H, Leiw YM (1997) Serum lipids and their relationship with other coronary risk factors in healthy subjects in a city clinic. Med J Malaysia 52:38–52

    CAS  Google Scholar 

  • Kumar A, Sivakanesan R (2009) Serum lipid profile abnormality in predicting the risk of myocardial infarction in elderly normolipidaemic patients in south Asia: a case-controlled study. Internet J Altern Med 6:2

    Google Scholar 

  • Mackay J, Mensah G (2004) Atlas of heart disease and stroke. World Health Organization, Geneva

    Google Scholar 

  • Mengesha AY (2006) Lipid profile among diabetes patients in Gaborone, Botswana. S Afr Med J 96:147–148

    Google Scholar 

  • Mgonda YM, Ramaiya KL, Swai ABM, Mc-Larty DG, George KM, Alberti M (1998) Insulin resistance and hypertension in non-obese Africans in Tanzania. Hypertension 31:114–118

    Article  CAS  Google Scholar 

  • Miller GJ, Miller NE (1975) Plasma high density lipoprotein concentration and development of ischemic heart disease. Lancet 1:16–19

    Article  CAS  Google Scholar 

  • Mosca L, Appel LJ, Benjamin EJ, Berra K, Chandra-Strobos N, Fabunmi RP, Grady D, Haan CK, Hayes SN, Judelson DR, Keenan NL, McBride P, Oparil S, Ouyang P, Oz MC, Mendelsohn ME, Pasternak RC, Pinn VW, Robertson RM, Schenck-Gustafsson K, Sila CA, Smith SC Jr, Sopko G, Taylor AL, Walsh BW, Wenger NK, Williams CL, American Heart Association (2004) Evidence-based guidelines for cardiovascular disease prevention in women. Circulation 109:672–693

    Article  Google Scholar 

  • Newnham HH (1993) Oestrogens and atherosclerotic vascular disease-lipid factors. Bailleres Clin Endocrinol Metab 7:61–93

    Article  CAS  Google Scholar 

  • Nigam PK, Narain VS, Hasan M (2004) Serum lipid profile in patients with acute myocardial infarction. Indian J Clin Biochem 19(1):67–70

    Article  CAS  Google Scholar 

  • Njelekela M, Negishi H, Nara Y, Tomohiro M, Kuga S, Noguchi T, Kanda T, Yamori M, Mashalla Y, Jian Liu L (2001) Cardiovascular risk factors in Tanzania: a revisit. Acta Trop 79(3):231–239

    Article  CAS  Google Scholar 

  • Nthangeni G, Steyn NP, Alberts M (2002) Dietary intake and barriers to dietary compliance in black type II diabetic patients attending primary health-care services. Public Health Nutr 5:329–338

    Article  Google Scholar 

  • Oparil S, Zaman MA, Calhoun DA (2003) Pathogenesis of hypertension. Ann Intern Med 139:761–776

    Article  CAS  Google Scholar 

  • Ryder REJ, Hayes TM, Mulligan IP, Kingwood JC, Williams S, Owens DR (1984) How soon after myocardial infarction should plasma lipid values be assessed. Br Med J 289:1651–1653

    Article  CAS  Google Scholar 

  • Saaddine JB, Engelgau MM, Beckles GL (2002) A diabetes report card for the United States: quality of care in the 1990s. Ann Intern Med 136:565

    Article  Google Scholar 

  • Saha MS, Sana NK, Shaha RK (2006) Serum lipid profile of hypertensive patients in the Northern region of Bangladesh. J Biosci 14:93–98

    Google Scholar 

  • Seyoum B, Abdulkadir J, Berhanu P (2003) Analysis of serum lipids and lipoproteins in Ethiopian diabetic patients. Ethiop Med J 41(1):1–8

    Google Scholar 

  • Singh RB, Beegom R, Ghosh S, Niaz MA, Rastogi V (1997) Epidemiological study of hypertension and its determinants in an urban population of North India. J Hum Hypertens 11:679–685

    Article  CAS  Google Scholar 

  • Smith S, Lall AM (2008) A study on lipid profile levels of diabetics and non-diabetics among Naini region of Allahabad, India. Turk J Biochem 33(4):138–141

    CAS  Google Scholar 

  • Swai AB, McLarty DG, Kitange HM, Kilima PM, Tatalla S, Keen N, Chuwa LM, Alberti KG (1993) Low prevalence of risk factors for coronary heart disease in rural Tanzania. Int J Epidemiol 22(4):651–659

    Article  CAS  Google Scholar 

  • Tao S, Li Y, Xiao Z, Cen R, Zhang H, Zhuo B, Chen P, Liao Y (1992) Serum lipids and their correlates in Chinese urban and rural population of Beijing and Guangzhou. PRC-USA Cardiovascular and Cardiopulmonary Epidemiology Research Group. J Epidemiol 21:893–903

    CAS  Google Scholar 

  • Tsimikas S, Bergmark C, Beyer RW (2003) Temporal increases in plasma markers of oxidized low density lipoprotein strongly reflect the presence of acute coronary syndrome. J Am Coll Cardiol 41:360–370

    Article  CAS  Google Scholar 

  • Ugwu CE, Ezeanyika LUS, Daikwo MA, Amana R (2009) Lipid profile of a population of diabetic patients attending Nigerian National Petroleum Corporation Clinic, Abuja. Afr J Biochem Res 3(3):066–069

    CAS  Google Scholar 

  • Vetter NJ, Strange RC, Adams W, Oliver MF (1974) Initial metabolic and hormonal response to acute myocardial infarction. Lancet 1(7852):284–289

    Article  CAS  Google Scholar 

  • Wenger NK (2003) Coronary heart disease: the female heart is vulnerable. Prog Cardiovasc Dis 46:199–229

    Article  Google Scholar 

  • Whelton PK (1994) Epidemiology of hypertension. Lancet 334:101–106

    Article  Google Scholar 

  • Wilsgaard T, Arnesen E (2004) Change in serum lipids and body mass index by age, sex, and smoking status: the Tromso study 1986–1995. Ann Epidemiol 14:265–273

    Article  Google Scholar 

  • Youmbissi TJ, Djoumessi S, Nouedoui C (2001) Profile lipidique d’un group d’hypertendus camerounais noir Africains. Med Afr Noire 31:114–118

    Google Scholar 

Download references

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Rizvi, N.B., Nagra, S.A. (2014). Literature Review: Cardiovascular Disorders and Lipid Profile. In: Minerals and Lipids Profiles in Cardiovascular Disorders in South Asia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34249-3_4

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