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Total Synthesis of Natural Products pp 103–130Cite as

Bryostatin 7

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Abstract

The bryostatins are a family of marine natural products originally isolated from the bryozoan Bugula neritina by Pettit and coworkers in the course of their search for new antineoplastic agents derived from marine organisms [1]. Later, during a large-scale isolation, 18 g of bryostatin 1, the first discovered and most naturally abundant member of this family, was obtained from a collection of 10,000 gallons of wet bryozoan [2].

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Notes

  1. 1.

    For current information, see: http://clinicaltrials.gov

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  1. Department of Chemistry and Biochemistry, University of Texas, Austin, Austin, TX, 78712, USA

    Yu Lu & Michael J. Krische

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  1. Yu Lu
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  1. Firestone Court 3, Skillman, 08558, New Jersey, USA

    Jie Jack Li

  2. , Dept. of Chemistry and Chemical Biology, Harvard University, Oxford Street 12, Cambridge, 02138, USA

    E.J. Corey

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Lu, Y., Krische, M.J. (2012). Bryostatin 7. In: Li, J., Corey, E. (eds) Total Synthesis of Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34065-9_5

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