Abstract
Mediastinal tumor is a collective term which includes a large number of developmental, inflammatory, and neoplastic masses.
In contrast to the leading symptoms and signs of most other chapters, only a part of the mediastinal tumors manifest themselves clinically, and up to 50 % of the cases are detected by chance on prenatal ultrasound or more frequently on chest x-rays performed for other reasons ##.
In addition, the possible symptoms and signs are many and diverse and are caused by compression (e.g., bronchi or trachea), involvement, or infiltration of the chest wall, the organs of the thoracic cavity, or spinal canal; that means that the precise location of the different disorders is important to a considerable degree for the symptomatology.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsBibliography
General: Textbooks, Anesthesia, Differential Diagnosis, Treatment
Anghelescu DL, Burgoyne LL, Liu T, Li CS, Pui CH, Hudson MM, Furman WL, Sandlund JT (2007) Clinical and diagnostic findings predict anesthetic complications in children presenting with malignant mediastinal masses. Paediatr Anaesth 17:1090–1098
Bölling T, Könemann S, Ernst I, Willich N (2008) Late effects of thoracic irradiation in children. Strahlenther Onkol 184:289–295
Cuendet A, Braun P (1982) Mediastinal tumoren. In: Bettex M et al (eds) Kinderchirur-gie, 2. Auflage, Thieme, Stuttgart
De Lorimier AA (1998) Respiratory problems related to the airway and lung. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol 1, 5th edn. Mosby, St. Louis
Findik G, Gezer S, Sirmali M, Turut H, Aydogdu K, Tastepe I, Karaoglanoglu N, Kaya S (2008) Thoracotomies in children. Pediatr Surg Int 24:721–725
Hecker WC (1988) Neubildungen im bereich des thoray. In: Schulte FJ, Spranger J (eds) Neubildungen im bereich des thorax. Fischer, Stuttgart
Jaggers J, Balsara K (2004) Mediastinal masses in children. Semin Thorac Cardiovasc Surg 16:201–208
Philippart AI, Farmer DL (1998) Benign mediastinal cysts and tumors. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol 1, 5th edn. Mosby, St. Louis
Saraswatula A, Mc Shane D, Tideswell D, Burke GA, Williams DM, Nicholson JC, Murray MJ (2009) Mediastinal masses masquerading as common respiratory conditions of childhood: a case series. Eur J Pediatr 168:1395–1399
Sharif K, Alton H, Clarke J, Desai M, Morland B, Parikh D (2006) Paediatric thoracic tumours presenting as empyema. Pediatr Surg Int 22:1009–1014
Tansel T, Onursal E, Dayloglu E, Basaran M, Sungur Z, Quamci E, Yilmazbayhan D, Eker R, Ertugrul T (2006) Childhood mediastinal masses in infants and children. Turk J Pediatr 48:8–12
Tsao K, St Peter SD, Sharp SW, Nair A, Andrews WS, Sharp RJ, Snyder CL, Ostlie DJ, Holcomb GW (2008) Current application of thoracoscopy in children. J Laparoendosc Adv Surg Tech A 18:131–135
Wright CD (2009) Mediastinal tumors and cysts in pediatric population. Thorac Surg Clin 19:47–61, vi
Section 8.1
Bayram AS, Gebitekin C, Bicer M (2007) Extrapulmonary sequestration mimicking mediastinal cyst: report of two identical cases. Tuberk Toraks 55:414–417
Bettschart RW, Bertschmann W, Bolliger CT (2008) Solide raumforderung im vorderen mediastinum (a solid tumour in the anterior mediastinum). Schweiz Med Forum 8:304–305
Blasimann B, Kuffer F, Bettex M (1977) Chirurgische Betrachtungen über die Thymushyperplasie (surgical consideration on hyperplasia of the thymus). Z Kinderchirurgie 21:214–230
De Backer A, Madern GC, Hakvoort-Cammel FG, Oosterhuis JW, Hazebroek FW (2006) Mediastinal germ cell tumors: clinical aspects and outcomes in 7 children. Eur J Pediatr Surg 16:318–322
De Backer A, Madern GC, Pieters R, Haentjens P, Hakvoort-Cammel FG, Oosterhuis JW, Hazebroek FW (2008) Influence of tumor site and histology on long-term survival in 193 children with extracranial germ cell tumors. Eur J Pediatr Surg 18:1–6
Gielda BT, Peng R, Coleman JL, Thomas CR, Cameron RB (2008) Treatment of early stage thymic tumors: surgery and radiation therapy. Curr Treat Options Oncol 9:258–268
Honda S, Morikawa T, Sasaki F, Okada T, Naito S, Itoh T, Kubota K, Todo S (2007) Cystic thymoma in a child: a rare case and review of the literature. Pediatr Surg Int 23:1015–1017
Hsueh C, Kuo TT, Tsang NM, Wu YC, Yang CP, Hung IJ (2006) Thymic lymphoepithelioma like carcinoma in children: clinicopathological features and molecular analysis. J Pediatr Hematol Oncol 28:785–790
Joshua BZ, Raveh E, Saute M, Schwarz M, Tobar A, Feinmesser R (2004) Familial thymic cyst. Int J Pediatr Otorhinolaryngol 68:573–579
Martino F, Avila LF, Encinas JL, Luis AL, Olivares P, Lassaletta L, Nistal M, Tovar JA (2006) Teratomas of the neck and mediastinum in children. Pediatr Surg Int 22:627–634
Rothstein DH, Voss SD, Isakoff M, Puder M (2005) Thymoma in a child: case report and review of the literature. Pediatr Surg Int 21:548–551
Salas Valverde S, Gamboa Y, Vega S, Barrantes M, Gonzales M, Zamora JB (2008) Diagnosis of anterior mediastinal mass lesions using the Chamberlain procedure in children. Pediatr Surg Int 24:935–937
Tomiyama N, Honda O, Tsubamoto M, Inoue A, Sumikawa H, Kuriyama K, Kusumoto M, Johkoh T, Nakamura H (2009) Anterior mediastinal tumors: diagnostic accuracy of CT and MRI. Eur J Radiol 69:280–288
Section 8.2
Bernasconi A, Yoo SJ, Golding F, Langer JC, Jaeggi ET (2007) Etiology and outcome of prenatally detected paracardial cystic lesions: a case series and review of the literature. Ultrasound Obstet Gynecol 29:388–394
Bluhm EC, Ronckers C, Hayashi RJ, Neglia JP, Mertens AC, Stovall M, Meadows AT, Mitby PA, Whitton JA, Hammond S, Barker JD, Donaldson SS, Robison LL, Inskip PD (2008) Cause-specific mortality and second cancer incidence after non-Hodgkin lymphoma: a report from the childhood cancer survivor study. Blood 111:4014–4021
Capra M, Hewitt M, Radford M, Hayward J, Weston CL, Machin D, Children’s Cancer and Leukaemia Group (2007) Long-term outcome in children with Hodgkin’s lymphoma: the United Kingdom Children’s cancer study group HD82 trial. Eur J Cancer 43:1171–1179
Eldar AH, Futerman B, Abrahami G et al (2009) Burkitt lymphoma in children: the Israeli experience. J Pediatr Hematol Oncol 31:428–436
Karnak I, Alehan D, Ekinci S, Büyükpamukcu N (2007) Cardiac rhabdomyoma as an unusual mediastinal mass in a newborn. Pediatr Surg Int 23:811–814
Piedimonte G, Wolford ET, Fordham LA et al (1997) Mediastinal lymphadenopathy caused by mycobacterium avium-intracellulare complex in a child with normal immunity: successful treatment anti-mycobacterial drugs and laser bronchoscopy. Pediatr Pulmonol 24:287–291
Soor GS, Chakrabarti MO, Luk A, Abraham JR, Phillips K, Butany J (2010) Prenatal intrapericardial teratomas: diagnosis and management. Cardiovasc Pathol 19:e1–e4
Tang YJ, Tang JY, Pan C, Xue HL, Chen J, Shen SH, Dong L, Zhou M, Wang YP, Gu LJ, Jiang H, Ye QD (2009) Clinical characteristics and treatment outcome of 36 cases with non-Hodgkin’s lymphoma arising from mediastinum in children. Zhonghua Er Ke Za Zhi 47:687–690
Venkateswaran RV, Barron DJ, Brawn WJ, Clarke JR, Desai M, Samuel M, Parikh DH (2005) A forgotten old disease: mediastinal tuberculous lymphadenitis in children. Eur J Cardiothorac Surg 27:401–404
Vogetseder A, Gengler C, Reineke T, Tinguely M (2011) Pädiatrische lymphom-diagnostik aktuelles aus der sicht der pathologen. Schweiz Med Forum 11:73–78
Von der Weid NX (2008) Adult life after surviving lymphoma in childhood. Support Care Cancer 16:339–345
Section 8.3
Alrabeeah A, Gillis DA, Giacomantonio M, Lau H (1988) Neurenteric cysts – a spectrum. J Pediatr Surg 23:752–754
Amra N, Amr SS (2009) Mediastinal lipoblastomatosis: report of a case with complex karyotype and review of the literature. Pediatr Dev Pathol 12:469–474
Bilik R, Ginzberg H, Superina RA (1995) Unconventional treatment of neuroenteric cyst in a newborn. J Pediatr Surg 30:115–117
Ebisu T, Odake G, Fujimoto M, Ueda S, Tsujii H, Morimoto M, Sawada T (1990) Neurenteric cysts with meningomyelocele or meningocele. Split notochord syndrome. Childs Nerv Syst 6:465–467
Häberle B, Hero B, Berthold F, von Schweinitz D (2002) Characteristics and outcome of thoracic neuroblastoma. Eur J Pediatr Surg 12:145–150
Kang CH, Kim YT, Jeon SH, Sung SW, Kim JH (2007) Surgical treatment of malignant mediastinal neurogenic tumors in children. Eur J Cardiothorac Surg 31:725–730
Kumar R, Jain R, Rao KM, Hussain N (2001) Intraspinal neurenteric cysts – report of three paediatric cases. Childs Nerv Syst 17:584–588
Rossi A, Cama A, Piatelli G, Ravegnani M, Biancheri R, Tortori-Donati P (2004) Spinal dysraphism: MR imaging rationale. J Neuroradiol 31:3–24
Savage JJ, Casey JN, McNeill IT, Sherman JH (2010) Neurenteric cysts of the spine. J Craniovertebr Junction Spine 1:58–63
Woo OH, Yong HS, Shin BK, Kim HK, Kang EY (2008) Wide spectrum of thoracic neurogenic tumours: a pictorial review of CT and pathological findings. Br J Radiol 81:668–676
Zhang KR, Jia HM, Pan EY, Wang LY (2006) Diagnosis and treatment of mediastinal enterogenous cysts in children. Chin Med Sci J 21:201–203
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kaiser, G.L. (2012). Mediastinal Tumors. In: Symptoms and Signs in Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31161-1_8
Download citation
DOI: https://doi.org/10.1007/978-3-642-31161-1_8
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-31160-4
Online ISBN: 978-3-642-31161-1
eBook Packages: MedicineMedicine (R0)