Skip to main content

Outer Membrane Vesicles and the Biofilm Formation

  • Chapter
  • First Online:
  • 1260 Accesses

Part of the book series: SpringerBriefs in Microbiology ((BRIEFSMICROBIOL))

Abstract

Plenty of outer membrane vesicles (OMVs) are often found associated with the parent bacteria forming a biofilm. The functions of these OMVs in the biofilm are discussed in this chapter. Additional genetic and other studies are required to decide the exact role of OMVs and DNA in the formation of biofilm.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Bomberger JM, Maceachran DP, Coutermarsh BA, Ye S, O’Toole GA, Stanton BA (2009) Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. PLoS Pathog 5:e1000382

    Article  PubMed  Google Scholar 

  • Chatterjee SN, Chaudhuri K (2006) Lipopolysaccharides of Vibrio cholerae: III. Biological functions. Biochim Biophys Acta 1762:1–16

    Article  PubMed  CAS  Google Scholar 

  • Chaudhuri K, Chatterjee SN (2009) Cholera toxins. Springer, Berlin

    Book  Google Scholar 

  • Costerton JW, Lewandowski Z, Caldwell DE, Korber DR, Lappin-Scott HM (1995) Microbial biofilms. Annu Rev Microbiol 49:711–745

    Article  PubMed  CAS  Google Scholar 

  • Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284:1318–1322

    Article  PubMed  CAS  Google Scholar 

  • Ellis TN, Kuehn MJ (2010) Virulence and immunomodulatory roles of bacterial outer membrane vesicles. Microbiol Mol Biol Rev 74:81–94

    Article  PubMed  CAS  Google Scholar 

  • Grenier D, Mayrand D (1987) Functional characterization of extracellular vesicles produced by Bacteroides gingivalis. Infect Immun 55:111–117

    PubMed  CAS  Google Scholar 

  • Inagaki S, Onishi S, Kuramitsu HK, Sharma A (2006) Porphyromonas gingivalis vesicles enhance attachment, and the leucine-rich repeat BspA protein is required for invasion of epithelial cells by “Tannerella forsythia”. Infect Immun 74:5023–5028

    Article  PubMed  CAS  Google Scholar 

  • Kamaguchi A, Nakayama K, Ichiyama S, Nakamura R, Watanabe T et al (2003a) Effect of Porphyromonas gingivalis vesicles on coaggregation of Staphylococcus aureus to oral microorganisms. Curr Microbiol 47:485–491

    Article  PubMed  CAS  Google Scholar 

  • Kamaguchi A, Ohyama T, Sakai E, Nakamura R, Watanabe T, Baba H, Nakayama K (2003b) Adhesins encoded by the gingipain genes of Porphyromonas gingivalis are responsible for co-aggregation with Prevotella intermedia. Microbiology 149:1257–1264

    Article  PubMed  CAS  Google Scholar 

  • Kierek K, Watnick PI (2003) The Vibrio cholerae O139 O-antigen polysaccharide is essential for Ca2 + -dependent biofilm development in sea water. Proc Natl Acad Sci USA 100:14357–14362

    Article  PubMed  CAS  Google Scholar 

  • Kulp A, Kuehn MJ (2010) Biological functions and biogenesis of secreted bacterial outer membrane vesicles. Annu Rev Microbiol 64:163–184

    Article  PubMed  CAS  Google Scholar 

  • Lawrence JR, Korber DR, Hoyle BD, Costerton JW, Caldwell DE (1991) Optical sectioning of microbial biofilms. J Bacteriol 173:6558–6567

    PubMed  CAS  Google Scholar 

  • MacDonald KL, Beveridge TJ (2002) Bactericidal effect of gentamicin-induced membrane vesicles derived from Pseudomonas aeruginosa PAO1 on gram-positive bacteria. Can J Microbiol 48:810–820

    Article  PubMed  CAS  Google Scholar 

  • Mashburn-Warren L (2008) Quinolone trafficking via outer membrane vesicles in Pseudomonas aeruginosa. Dissertation for the Doctor of Philosophy Thesis, University of Texas, Austin

    Google Scholar 

  • Mayrand D, Grenier D (1989) Biological activities of outer membrane vesicles. Can J Microbiol 35:607–613

    Article  PubMed  CAS  Google Scholar 

  • Mizunoe Y, Wai SN, Takade A, Yoshida SI (1999) Isolation and characterization of rugose form of Vibrio cholerae O139 strain MO10. Infect Immun 67:958–963

    PubMed  CAS  Google Scholar 

  • Nesper J, Lauriano CM, Klose KE, Kapfhammer D, Kraiss A, Reidl J (2001) Characterization of Vibrio cholerae O1 El tor galU and galE mutants: influence on lipopolysaccharide structure, colonization, and biofilm formation. Infect Immun 69:435–445

    Article  PubMed  CAS  Google Scholar 

  • Olczak T, Wojtowicz H, Ciuraszkiewicz J, Olczak M (2010) Species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of Porphyromonas gingivalis HmuY. BMC Microbiol 10:134

    Article  PubMed  Google Scholar 

  • Patrick S, McKenna JP, O’Hagan S, Dermott E (1996) A comparison of the haemagglutinating and enzymic activities of Bacteroides fragilis whole cells and outer membrane vesicles. Microb Pathog 20:191–202

    Article  PubMed  CAS  Google Scholar 

  • Ramsey MM, Whiteley M (2004) Pseudomonas aeruginosa attachment and biofilm development in dynamic environments. Mol Microbiol 53:1075–1087

    Article  PubMed  CAS  Google Scholar 

  • Renelli M, Matias V, Lo RY, Beveridge TJ (2004) DNA-containing membrane vesicles of Pseudomonas aeruginosa PAO1 and their genetic transformation potential. Microbiology 150:2161–2169

    Article  PubMed  CAS  Google Scholar 

  • Rocchetta HL, Burrows LL, Lam JS (1999) Genetics of O-antigen biosynthesis in Pseudomonas aeruginosa. Microbiol Mol Biol Rev 63:523–553

    PubMed  CAS  Google Scholar 

  • Schooling SR, Beveridge TJ (2006) Membrane vesicles: an overlooked component of the matrices of biofilms. J Bacteriol 188:5945–5957

    Article  PubMed  CAS  Google Scholar 

  • Schooling SR, Hubley A, Beveridge TJ (2009) Interactions of DNA with biofilm-derived membrane vesicles. J Bacteriol 191:4097–4102

    Article  PubMed  CAS  Google Scholar 

  • Unal CM, Schaar V, Riesbeck K (2010) Bacterial outer membrane vesicles in disease and preventive medicine. Semin Immunopathol 33:395–408

    Article  PubMed  Google Scholar 

  • Wai SN, Mizunoe Y, Takade A, Kawabata SI, Yoshida SI (1998) Vibrio cholerae O1 strain TSI-4 produces the exopolysaccharide materials that determine colony morphology, stress resistance, and biofilm formation. Appl Environ Microbiol 64:3648–3655

    PubMed  CAS  Google Scholar 

  • Watnick PI, Kolter R (1999) Steps in the development of a Vibrio cholerae El Tor biofilm. Mol Microbiol 34:586–595

    Article  PubMed  CAS  Google Scholar 

  • Watnick PI, Fullner KJ, Kolter R (1999) A role for the mannose-sensitive hemagglutinin in biofilm formation by Vibrio cholerae El Tor. J Bacteriol 181:3606–3609

    PubMed  CAS  Google Scholar 

  • Whitchurch CB, Tolker-Nielsen T, Ragas PC, Mattick JS (2002) Extracellular DNA required for bacterial biofilm formation. Science 295:1487

    Article  PubMed  CAS  Google Scholar 

  • Yildiz FH, Schoolnik GK (1999) Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation. Proc Natl Acad Sci USA 96:4028–4033

    Article  PubMed  CAS  Google Scholar 

  • Yildiz FH, Dolganov NA, Schoolnik GK (2001) VpsR, a Member of the Response Regulators of the Two-Component Regulatory Systems, Is Required for Expression of vps Biosynthesis Genes and EPS(ETr)-Associated Phenotypes in Vibrio cholerae O1 El Tor. J Bacteriol 183:1716–1726

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. N. Chatterjee .

Rights and permissions

Reprints and permissions

Copyright information

© 2012 The Author(s)

About this chapter

Cite this chapter

Chatterjee, S.N., Chaudhuri, K. (2012). Outer Membrane Vesicles and the Biofilm Formation. In: Outer Membrane Vesicles of Bacteria. SpringerBriefs in Microbiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30526-9_5

Download citation

Publish with us

Policies and ethics