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Optical Coherence Tomography pp 157–174Cite as

Evaluation of the Blood–Retinal Barrier with Optical Coherence Tomography

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Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

The imaging technique of optical coherence tomography (OCT) has opened a unique world in the area of ophthalmology, specifically in imaging the human retina. The findings based on the use of OCT have brought new knowledge of the retina and the changes that occur in the retina that previously have not been available in vivo. In addition to the current uses of OCT, new fields of application have recently emerged, and it is believed that additional ones will gain maturity in the near future. In this chapter, we demonstrate the potential use of OCT in the assessment of changes on the blood–retinal barrier and in the neuronal tissue related to the aging process.

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Acknowledgments

The authors would like to thank Dr. Melissa Horne and Carl Zeiss Meditec (Dublin, CA, USA) for their support on obtaining access to OCT data and AIBILI - The Centre for Clinical Trials (CEC) technicians for their support in managing data, working with patients, and performing scans. This study is supported in part by the Fundação para a Ciência e a Tecnologia (FCT) under the research project PTDC/SAU-BEB/103151/2008 and program COMPETE (FCOMP-01-0124-FEDER-010930).

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Authors and Affiliations

  1. IBILI-Institute for Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Portugal

    Rui Bernardes

  2. AIBILI-Association for Innovation and Biomedical Research on Light and Image, Azinhaga Santa Comba, 3000-548, Coimbra, Portugal

    Rui Bernardes & José Cunha-Vaz

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  1. Rui Bernardes
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  2. José Cunha-Vaz
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Correspondence to Rui Bernardes .

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Editors and Affiliations

  1. , Faculty of Medicine, University of Coimbra, Azinhaga Sta. Comba, Celas, Coimbra, 3000-548, Portugal

    Rui Bernardes

  2. , Faculty of Medicine, University of Coimbra, Azinhaga Sta. Comba, Celas, Coimbra, 3000-548, Portugal

    José Cunha-Vaz

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Bernardes, R., Cunha-Vaz, J. (2012). Evaluation of the Blood–Retinal Barrier with Optical Coherence Tomography. In: Bernardes, R., Cunha-Vaz, J. (eds) Optical Coherence Tomography. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27410-7_8

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  • DOI: https://doi.org/10.1007/978-3-642-27410-7_8

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-27409-1

  • Online ISBN: 978-3-642-27410-7

  • eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)

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