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Multidisciplinary Management of Rectal Cancer pp 105–116Cite as

When Should Preoperative Short-Course Radiotherapy or Long-Course Chemoradiotherapy Be Performed?

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Abstract

Traditionally, there has been a high local recurrence rate after radical surgery in rectal cancer, and 10–40% of patients require a permanent stoma. Both short-course preoperative radiotherapy (SCPRT) and long-course preoperative chemoradiation (CRT) are advocated to reduce this risk of local recurrence and enable a curative resection. The role of preoperative radiotherapy to facilitate sphincter sparing surgery remains highly contentious.

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Authors and Affiliations

  1. Department of Clinical Oncology, University of Leeds, St James’s Institute of Oncology, St James’s University Hospital, Beckett St, LS9 7TF, Leeds, UK

    David Sebag-Montefiore

  2. Department of Clinical Oncology, Mount Vernon Centre for Cancer Treatment, Rickmansworth Rd, Northwood, Middlesex, HA6 2RN, UK

    Robert Glynne-Jones

Authors
  1. David Sebag-Montefiore
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  2. Robert Glynne-Jones
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Correspondence to David Sebag-Montefiore .

Editor information

Editors and Affiliations

  1. , Dept. of Radiation Therapy, Università Cattolica S.Cuore, Largo A.Gemelli 8, Rome, 00168, Italy

    Vincenzo Valentini

  2. Klinik und Poliklinik Innere Medizin IV, Abt. Hämatologie und Onkologie, Universitätsklinikum Halle-Wittenberg, Ernst-Grube-Str. 40, Halle, 06097, Sachsen-Anhalt, Germany

    Hans-Joachim Schmoll

  3. Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands

    Cornelis J. H. van de Velde

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© 2012 Springer-Verlag Berlin Heidelberg

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Sebag-Montefiore, D., Glynne-Jones, R. (2012). When Should Preoperative Short-Course Radiotherapy or Long-Course Chemoradiotherapy Be Performed?. In: Valentini, V., Schmoll, HJ., van de Velde, C. (eds) Multidisciplinary Management of Rectal Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25005-7_12

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  • DOI: https://doi.org/10.1007/978-3-642-25005-7_12

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-25004-0

  • Online ISBN: 978-3-642-25005-7

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