V Latin American Congress on Biomedical Engineering CLAIB 2011 May 16-21, 2011, Habana, Cuba

Volume 33 of the series IFMBE Proceedings pp 108-111

Recubrimientos de Hidroxiapatita Nanocristalina – Preparación, Caracterización y Evaluación de la Bioactividad

  • E. PeónAffiliated withCentro de Biomateriales/Cerámicas y Composites, Universidad de La Habana Email author 
  • , I. N. BastosAffiliated withPolytechnic Institute, Universidade do Estado do Rio de Janeiro
  • , J. M. GranjeiroAffiliated withUniversidade Federal Fluminense
  • , A. A. ElhadadAffiliated withCentro Nacional de Investigaciones Metalúrgicas, CSIC
  • , A. Jiménez-MoralesAffiliated withDepartamento de Ciencia e Ingeniería de Materiales e Ingeniería Química, Universidad Carlos III de Madrid
  • , V. BarrancoAffiliated withInstituto de Ciencia de Materiales de Madrid, CSIC
  • , J. C. G. SierraAffiliated withCentro Nacional de Investigaciones Metalúrgicas, CSIC
  • , G. D. SoaresAffiliated withCOPPE/Programa de Ingeniería Metalúrgica y Materiales, UFRJ

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The coating of metallic alloys with bioactive ceramics aims to accelerate bone formation around implant, contributing to its fixation. In this paper, the deposition of bioactive hydroxyapatite ceramic by sol-gel method on Ti-6Al-4V alloy sheets was studied. Coatings prepared from hydroxyapatite sol have been accomplished by dip-coating technique on non-toxic Ti-6Al-4V alloy for biomedical applications. The coating layer was characterized by X-ray diffraction provided valuable information about the phase transformation, identification of the phases developed and degree of crystallinity. Scanning electron microscopy was applied to study the surface morphology and coating adhesion to substrate was evaluated by shear testing (ASTM F 1044-05). The obtained results show that all the prepared samples are ceramic nanopowders with crystal structure and composition like hydroxyapatite, with small deviations from the one present in the human bone. The corrosion behavior of the resulting hydroxyapatite coatings in a simulated body fluid (SBF) was studied by electrochemical impedance spectroscopy. The hydroxyapatite coated Ti-6Al-4V alloy displayed excellent bioactivity when soaked in the SBF and acceptable corrosion protection behavior. The citocompatibility test according to ISO 10993-5 standard shows that sol-gel coating did not provoke cell dead.

Palabras claves

ceramics hydroxyapatite sol-gel biomaterials “in vitro” tests cytotoxicity