Abstract
The shape of anodal strength-interval curves and make and break excitation mechanisms are investigated in a 2D anisotropic Bidomain model, with different membrane models and action potential durations, and in a 3D rotational anisotropic Bidomain model, with axisymmetric or orthotropic conductivity properties. The results have shown that the LRd model with a long intrinsic APD exhibits a systolic dip threshold lower than the diastolic threshold, in agreement with previous experimental data. The spatial and temporal analysis of the excitation patterns indicates a novel anode make excitation mechanism with delayed propagation within the transition from break to make mechanisms.
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Colli-Franzone, P., Pavarino, L.F., Scacchi, S. (2011). Anode Make and Break Excitation Mechanisms and Strength-Interval Curves: Bidomain Simulations in 3D Rotational Anisotropy. In: Metaxas, D.N., Axel, L. (eds) Functional Imaging and Modeling of the Heart. FIMH 2011. Lecture Notes in Computer Science, vol 6666. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21028-0_1
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DOI: https://doi.org/10.1007/978-3-642-21028-0_1
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