Abstract
Here the mode of small supernumerary marker chromosome (sSMC) inheritance, i.e., if it is de novo or familial, is treated. Also sSMC and Bchromosomes are compared, as there are several similarities between them: both represent a heterogeneous collection of chromosomes added to the standard karyotype, both are small, both may consist of heterochromatic and/or euchromatic material, in both there is predominance of maternal transmission, and both demonstrate a tendency for mitotic instability.
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References
Anderlid BM, Sahlen S, Schoumans J, Holmberg E, Ahsgren I, Mortier G, Speleman F, Blennow E (2001) Detailed characterization of 12 supernumerary ring chromosomes using micro-FISH and search for uniparental disomy. Am J Med Genet A 99:223–233
Baldwin EL, May LF, Justice AN, Martin CL, Ledbetter DH (2008) Mechanisms and consequences of small supernumerary marker chromosomes: from Barbara McClintock to modern genetic-counseling issues. Am J Hum Genet 82:398–410
Camacho JPM (2004) B chromosomes in the eukaryote genome. Cytogenet Genome Res 106:147–410
Camacho JPM, Shaw MW, López-León MD, Pardo MC, Cabrero J (1997) Population dynamics of a selfish B chromosome neutralized by the standard genome in the grasshopper Eyprepocnemis plorans. Am Nat 149:1030–1050
Dalprà L, Giardino D, Finelli P, Corti C, Valtorta C, Guerneri S, Ilardi P, Fortuna R, Coviello D, Nocera G, Amico FP, Martinoli E, Sala E, Villa N, Crosti F, Chiodo F, di Cantogno LV, Savin E, Croci G, Franchi F, Venti G, Donti E, Migliori V, Pettinari A, Bonifacio S, Centrone C, Torricelli F, Rossi S, Simi P, Granata P, Casalone R, Lenzini E, Artifoni L, Pecile V, Barlati S, Bellotti D, Caufin D, Police A, Cavani S, Piombo G, Pierluigi M, Larizza L (2005) Cytogenetic and molecular evaluation of 241 small supernumerary marker chromosomes: cooperative study of 19 Italian laboratories. Genet Med 7:620–625
Ing PS, Lubinsky MS, Smith SD, Golden E, Sanger WG, Duncan A (1987) Cat-eye syndrome with different marker chromosomes in a mother and daughter. Am J Med Genet A 26:621–628
Liehr T (2006) Familial small supernumerary marker chromosomes are predominantly inherited via the maternal line. Genet Med 8:459–462
Liehr T (2011a) The sSMC homepage. http://www.med.uni-jena.de/fish/sSMC/00START.htm. Cited 10 Jan 2011
Liehr T, Weise A (2007) Frequency of small supernumerary marker chromosomes in prenatal, newborn, developmentally retarded and infertility diagnostics. Int J Mol Med 19:719–731
Liehr T, Mrasek K, Kosyakova N, Ogilvie CM, Vermeesch J, Trifonov V, Rubtsov N (2008a) Small supernumerary marker chromosomes (sSMC) in humans; are there B chromosomes hidden among them. Mol Cytogenet 1:12
Liehr T, Wegner R-D, Stumm M, Joksi G, Polityko A, Kosyakova N, Ewers E, Reich D, Wagner R, Weise A (2008b) Pallister-Killian syndrome. Rare phenotypic features and variable karyotypes. Balk J Med Gen 11:65–67
Manvelyan M, Riegel M, Santos M, Fuster C, Pellestor F, Mazaurik ML, Schulze B, Polityko A, Tittelbach H, Reising-Ackermann G, Belitz B, Hehr U, Kelbova C, Volleth M, Gödde E, Anderson J, Küpferling P, Köhler S, Duba HC, Dufke A, Aktas D, Martin T, Schreyer I, Ewers E, Reich D, Mrasek K, Weise A, Liehr T (2008) Thirty-two new cases with small supernumerary marker chromosomes detected in connection with fertility problems: detailed molecular cytogenetic characterization and review of the literature. Int J Mol Med 21:705–714
Mau-Holzmann UA (2005) Somatic chromosomal abnormalities in infertile men and women. Cytogenet Genome Res 111:317–336
Mears AJ, El-Shanti H, Murray JC, McDermid HE, Patil SR (1995) Minute supernumerary ring chromosome 22 associated with cat eye syndrome: further delineation of the critical region. Am J Hum Genet 57:667–673
Morel F, Roux C, Bresson JL (2000) Segregation of sex chromosomes in spermatozoa of 46, XY/47, XXY men by multicolour fluorescence in-situ hybridization. Mol Hum Reprod 6:566–570
Oracova E, Musilova P, Kopecna O, Rybar R, Vozdova M, Vesela K, Rubes J (2009) Sperm and embryo analysis in a carrier of supernumerary inv dup(15) marker chromosome. J Androl 30:233–239
Ridler MA, Berg JM, Pendrey MJ, Saldana P, Timothy JA (1970) Familial occurrence of a small, supernumerary metacentric chromosome in phenotypically normal women. J Med Genet 7:148–152
Schinzel A (2001) Catalogue of unbalanced chromosome aberrations in man. De Gruyter, Berlin, pp 19–22
Shah K, Sivapalan G, Gibbons N, Tempest H, Griffin DK (2003) The genetic basis of infertility. Reproduction 126:13–25
Smits LJ, de Bie RA, Essed GG, van den Brandt PA (2005) Time to pregnancy and sex of offspring: cohort study. BMJ 331:1437–1438
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Liehr, T. (2012). Inheritance of Small Supernumerary Marker Chromosomes. In: Small Supernumerary Marker Chromosomes (sSMC). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20766-2_2
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DOI: https://doi.org/10.1007/978-3-642-20766-2_2
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