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General Role of Imaging in the Evaluation of Diffuse Infiltrative and Air ways Diseases

  • Chapter
Book cover Functional Imaging of the Chest

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Patients with lung disease are usually investigated by a combination of imaging and physiological tests. Historically, there has been only modest expectation that there should be obvious concordance between the results of these two different types of test (which assess structure and function respectively). For example, some individuals with functional evidence of advanced emphysema have a normal chest radiograph; conversely, some patients with obvious radiographic features of pulmonary sarcoidosis have pulmonary function tests within the normal predicted range (Fig. 1.1). The failure to successfully reconcile structural abnormalities with functional disturbances led to a somewhat nihilistic view, typified by a remark in the 1970s of an anonymous physiologist: “what you see, or think you see (on a chest radiograph), is a pale reflection of physiological reality.” Although insights into the pathophysiology of lung disease were gleaned from chest radiography by meticulous analysis, for example in the evaluation of pulmonary oedema (Miniati et al. 1988; Pistolesi et al. 1986), there were, and are, several constraints on the extent and level of information that could be extracted from a chest radiograph.

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Hansell, D.M. (2004). General Role of Imaging in the Evaluation of Diffuse Infiltrative and Air ways Diseases. In: Kauczor, HU. (eds) Functional Imaging of the Chest. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18621-9_1

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