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Biocommunication in Soil Microorganisms pp 369–401Cite as

Integration of Cell-to-Cell Signals in Soil Bacterial Communities

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Part of the book series: Soil Biology ((SOILBIOL,volume 23))

Abstract

Soil bacteria employ multitiered signaling mechanisms to structure multicellular communities, coordinate behaviors within these communities, and to interact with their eukaryotic hosts. Bacteria deploy signals to estimate numbers of bacterial cells within diffusion-limited environments and then modulate gene expression in response to changes in population densities. This behavior is known as “quorum sensing” (QS). Many Gram-negative bacteria use N-acyl homoserine lactones (AHLs) as QS signals. In γ-proteobacteria, AHL-mediated signaling itself is regulated by the orthologs of the GacS/GacA two-component global regulatory system. In response to an unknown signal, GacS/GacA orthologs control genes involved in quorum sensing, virulence, stress survival, motility, and the production of secondary metabolites and exoenzymes. GacS is an unorthodox sensor kinase predicted to autophosphorylate in the presence of a currently unknown endogenous signal. In Pseudomonas spp., GacS interacts with the orphan sensor kinases RetS and LadS, which modulate activity of GacS.

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Acknowledgments

Preparation of this manuscript was supported by USDA NRI 2007-35319-18158 (M.T. and J.B.R.), and CRIS project FLA-SWS-004984 of Florida Agricultural Experimental Station.

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Authors and Affiliations

  1. Soil and Water Sciences Department, Genetics Institute, University of Florida – Institute of Food and Agricultural Sciences (IFAS), 1376 Mowry Rd, Gainesville, FL, USA

    Max Teplitski & Mengsheng Gao

  2. Glycosyn Inc, Boston, MA, USA

    Massimo Merighi

  3. Department of Biology, University of Dayton, Dayton, OH, USA

    Jayne Robinson

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  1. Max Teplitski
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  2. Massimo Merighi
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  3. Mengsheng Gao
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  4. Jayne Robinson
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Correspondence to Max Teplitski .

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  1. Telos - Philosophische Praxis, Vogelsangstr. 18c18c, Bürmoos, 5111, Austria

    Günther Witzany

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Teplitski, M., Merighi, M., Gao, M., Robinson, J. (2011). Integration of Cell-to-Cell Signals in Soil Bacterial Communities. In: Witzany, G. (eds) Biocommunication in Soil Microorganisms. Soil Biology, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14512-4_14

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