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Thermal Aspects of Irreversible Electroporation

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Book cover Irreversible Electroporation

Part of the book series: Series in Biomedical Engineering ((BIOMENG))

Abstract

Irreversible electroporation (IRE) is a promising new technique for the ablation of tumors and arrhythmogenic regions in the heart (Davalos, Mir et al. 2005; Edd, Horowitz et al. 2006; Al-Sakere, Andre et al. 2007; Edd and Davalos 2007; Onik, Mikus et al. 2007; Rubinsky 2007). One of its primary advantages over other ablation techniques lies in its mechanism to kill undesirable cells by affecting the cell membrane without thermally damaging major blood vessels, connective tissue, nerves and the surrounding tissue. IRE’s ability to create complete and predictable tissue ablation with sharp transition between normal and necrotic tissue will have great advantages in a variety of medical applications (Rubinsky 2007).

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Author information

Authors and Affiliations

  1. School of Biomedical Engineering and Sciences, Virginia Tech, Wake Forest University, Blacksburg, VA, 24061, USA

    Rafael V. Davalos & Paulo A. Garcia

  2. Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, Boston, MA, 02114, USA

    Jon F. Edd

  3. Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, 37212, USA

    Jon F. Edd

Authors
  1. Rafael V. Davalos
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  2. Paulo A. Garcia
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  3. Jon F. Edd
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Editor information

Editors and Affiliations

  1. University of California at Berkeley, Berkeley, CA, USA

    Boris Rubinsky

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Davalos, R.V., Garcia, P.A., Edd, J.F. (2010). Thermal Aspects of Irreversible Electroporation. In: Rubinsky, B. (eds) Irreversible Electroporation. Series in Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05420-4_5

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  • DOI: https://doi.org/10.1007/978-3-642-05420-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-05419-8

  • Online ISBN: 978-3-642-05420-4

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