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Malassezia and the Skin pp 139–173Cite as

Malassezia Species and Immunity: Host–Pathogen Interactions

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Malassezia species stimulate both the cellular and humoral immune responses in healthy humans and also in patients with Malassezia-associated diseases. The cellular immune responses to Malassezia yeasts often appear to be heightened in patients with disease. It has also become clear that Malassezia has two phenotypes - one, which is immuno-stimulatory and may occur in disease states, and the second, which is immunosuppressive and may occur during commensal carriage. Although there are fewer studies related to dogs when compared with humans, dogs also develop a spectrum of humoral and cellular immune responses to their commensal yeast, Malassezia pachydermatis, both in health and in disease.

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  1. Mycology Reference Centre, Department of Microbiology, Leeds General Infirmary, Leeds, LS1 3EX, UK

    H. Ruth Ashbee

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  1. H. Ruth Ashbee
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  2. Ross Bond
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Correspondence to H. Ruth Ashbee .

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  1. Centraalbureau voor Schimmelcultures, Uppsalalaan 8, 3584, CT, Utrecht, The Netherlands

    Teun Boekhout PhD

  2. Department of Dermatology and Andrology, Justus Liebig University Giessen, Gaffykstrasse 14, 35385, Giessen, Germany

    Peter Mayser MD

  3. INSERM, 5 rue de la Huchette, 61400, Mauves sur Huisne, France

    Eveline Guého-Kellermann PhD

  4. Mycology Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, 11527, Greece

    Aristea Velegraki PhD (Professor) (Professor)

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Ashbee, H.R., Bond, R. (2010). Malassezia Species and Immunity: Host–Pathogen Interactions. In: Boekhout, T., Mayser, P., Guého-Kellermann, E., Velegraki, A. (eds) Malassezia and the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03616-3_5

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