Skip to main content

Metabolic Control Theory

  • Chapter
  • First Online:
Book cover Molecular and Cellular Enzymology
  • 2062 Accesses

Abstract

The life of a cell relies on multiple mechanisms for regulating the diverse reactions that constitute metabolism, as has been previously explained. Some mechanisms are provided by the intrinsic properties of enzymes, such as allosteric enzymes. Others stem from the spatial organisation that allows modulation of enzymatic activity, as with membrane enzymes and multi-enzyme complexes. In these complexes the product of an enzyme reaction is frequently the substrate for the subsequent reaction. In this respect, the metabolic pathway can be considered to be an organised system.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Bibliography

Reviews

  • Hess B. & Boiteux A. –1971– Oscillatory phenomena in biochemistry, in Annu. Rev. Biochem. 40, 237–258.

    Article  PubMed  CAS  Google Scholar 

  • Silman I.H. & Katchalski E. –1966– Water-insoluble derivatives of enzymes, antigens and antibodies, in Annu. Rev. Biochem. 35, 873–908.

    Article  PubMed  CAS  Google Scholar 

  • Srere P.A. –1988– Complexes of sequential metabolic enzymes, in Annu. Rev. Biochem. 56, 89–124.

    Article  Google Scholar 

Specialised Articles

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jeannine Yon-Kahn .

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Yon-Kahn, J., Hervé, G. (2009). Metabolic Control Theory. In: Molecular and Cellular Enzymology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01228-0_19

Download citation

Publish with us

Policies and ethics