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Pruritic Urticarial Papules and Plaques of Pregnancy

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Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a benign, extremely pruritic, inflammatory eruption of the third trimester of primigravida pregnancies, characterized by urticarial papules and plaques localized first to the abdomen [2, 27, 53]. It clears at delivery and it is the most common of the gestational dermatoses [53].

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References

  1. Ahmed AR, Kaplan R (1981) Pruritic urticarial papules and plaques of pregnancy. J Am Acad Dermatol 4:679–681

    Article  PubMed  CAS  Google Scholar 

  2. Al-Fares SI, Jones S V, Black MM (2001) The specific dermatoses of pregnancy: a re-appraisal. J Eur Acad Dermatol Venereol 15:197–206

    Article  PubMed  CAS  Google Scholar 

  3. Alcalay J, David M, Sandbank M (1986) Facial involvement in pruritic urticarial papules and plaques of pregnancy. J Am Acad Dermatol 15:1048

    Article  PubMed  CAS  Google Scholar 

  4. Alcalay J, Ingber A, David M et al (1987) Pruritic urticarial papules and plaques of pregnancy. A review of 21 cases. J Reprod Med 32:315–316

    PubMed  CAS  Google Scholar 

  5. Alcalay J, Ingber A, Kafri B et al (1988) Hormonal evaluation and autoimmune background in pruritic urticarial papules and plaques of pregnancy. Am J Obstet Gynecol 158:417–420

    PubMed  CAS  Google Scholar 

  6. Aractingi S, Berkane N, Bertheau P et al (1998) Fetal DNA in skin of polymorphic eruptions of pregnancy. Lancet 352:1898–1901

    Article  PubMed  CAS  Google Scholar 

  7. Aronson IK, Bond S, Fiedler VC et al (1998) Pruritic urticarial papules and plaques of pregnancy: clinical and immunopathologic observations in 57 patients. J Am Acad Dermatol 39:933–939

    Article  PubMed  CAS  Google Scholar 

  8. Beckett MA, Goldberg NS (1991) Pruritic urticarial plaques and papules of pregnancy and skin distention. Arch Dermatol 127:125–126

    Article  PubMed  CAS  Google Scholar 

  9. Beltrani V P, Beltrani VS (1992) Pruritic urticarial papules and plaques of pregnancy: a severe case requiring early delivery for relief of symptoms. J Am Acad Dermatol 26:266–267

    Article  PubMed  CAS  Google Scholar 

  10. Black M, Stephens C (1989) The specific dermatoses of pregnancy: the British perspective. Adv Dermatol 7:105–127

    Google Scholar 

  11. Black MM (1997) Progress and new directions in the investigation of the specific dermatoses of pregnancy. Keio J Med 46:40–41

    PubMed  CAS  Google Scholar 

  12. Borradori L, Saurat JH (1994) Specific dermatoses of pregnancy. Toward a comprehensive view? Arch Dermatol 130:778–780

    Article  PubMed  CAS  Google Scholar 

  13. Bourne G (1962) Toxaemic rash of pregnancy. Proc R Soc Med 55:462–464

    PubMed  CAS  Google Scholar 

  14. Bunker CB, Erskine K, Rustin MH et al (1990) Severe polymorphic eruption of pregnancy occurring in twin pregnancies. Clin Exp Dermatol 15:228–231

    Article  PubMed  CAS  Google Scholar 

  15. Callen JP (1984) Pregnancy's effects on the skin. Common and uncommon changes. Postgrad Med 75:138–145

    PubMed  CAS  Google Scholar 

  16. Callen J P, Hanno R (1981) Pruritic urticarial papules and plaques of pregnancy (PUPPP). A clinicopathologic study. J Am Acad Dermatol 5:401–405

    Article  PubMed  CAS  Google Scholar 

  17. Campbell DM (1986) Maternal adaptation in twin pregnancy. Semin Perinatol 10:14–18

    PubMed  CAS  Google Scholar 

  18. Carli P, Tarocchi S, Mello G et al (1994) Skin immune system activation in pruritic urticarial papules and plaques of pregnancy. Int J Dermatol 33:884–885

    Article  PubMed  CAS  Google Scholar 

  19. Carruthers A (1993) Pruritic urticarial papules and plaques of pregnancy. J Am Acad Dermatol 29:125

    Article  PubMed  CAS  Google Scholar 

  20. Catanzarite V, Quirk JG Jr (1990) Papular dermatoses of pregnancy. Clin Obstet Gynecol 33:754–758

    Article  PubMed  CAS  Google Scholar 

  21. Charles-Holmes R (1989) Polymorphic eruption of pregnancy. Semin Dermatol 8:18–22

    PubMed  CAS  Google Scholar 

  22. 11/10/2008 2:02PM

    PubMed  CAS  Google Scholar 

  23. Cohen LM, Capeless EL, Krusinski PA et al (1989) Pruritic urticarial papules and plaques of pregnancy and its relationship to maternal-fetal weight gain and twin pregnancy. Arch Dermatol 125:1534–1536

    Article  PubMed  CAS  Google Scholar 

  24. Dacus JV (1990) Pruritus in pregnancy. Clin Obstet Gynecol 33:738–745

    Article  PubMed  CAS  Google Scholar 

  25. Elling S V, McKenna P, Powell FC (2000) Pruritic urticarial papules and plaques of pregnancy in twin and triplet pregnancies. J Eur Acad Dermatol Venereol 14:378–381

    Article  PubMed  CAS  Google Scholar 

  26. Errickson C V, Matus NR (1994) Skin disorders of pregnancy. Am Fam Physician 49:605–610

    PubMed  CAS  Google Scholar 

  27. Eudy SF, Baker GF (1990) Dermatopathology for the obstetrician. Clin Obstet Gynecol 33:728–737

    Article  PubMed  CAS  Google Scholar 

  28. Fox GN (1986) Pruritic urticarial papules and plaques of pregnancy. Am Fam Physician 34:191–195

    PubMed  CAS  Google Scholar 

  29. Fuhrman L (2000) Common dermatoses of pregnancy. J Perinat Neonatal Nurs 14:1–16

    PubMed  CAS  Google Scholar 

  30. Hays PM, Smeltzer JS (1986) Multiple gestation. Clin Obstet Gynecol 29:264–285

    PubMed  CAS  Google Scholar 

  31. Helm TN, Valenzuela R (1992) Continuous dermoepidermal junction IgM detected by direct immunofluorescence: a report of nine cases. J Am Acad Dermatol 26:203–206

    Article  PubMed  CAS  Google Scholar 

  32. Holmes RC, Black MM (1982) The specific dermatoses of pregnancy: a reappraisal with special emphasis on a proposed simplified clinical classification. Clin Exp Dermatol 7:65–73

    Article  PubMed  CAS  Google Scholar 

  33. Holmes RC, Black MM (1983) The specific dermatoses of pregnancy. J Am Acad Dermatol 8:405–412

    Article  PubMed  CAS  Google Scholar 

  34. Holmes RC, Black MM, Dann J et al (1982) A comparative study of toxic erythema of pregnancy and herpes gestationis. Br J Dermatol 106:499–510

    Article  PubMed  CAS  Google Scholar 

  35. Im S, Lee ES, Kim W et al (2000) Expression of progesterone receptor in human keratinocytes. J Korean Med Sci 15:647–654

    PubMed  CAS  Google Scholar 

  36. Ingber A, Alcalay J, Sandbank M (1988) Multiple dermal fibroblasts in patients with pruritic urticarial papules and plaques of pregnancy. A clue to the etiology? Med Hypotheses 26:11–12

    Article  PubMed  CAS  Google Scholar 

  37. Jurecka W, Holmes RC, Black MM et al (1983) An immunoelectron microscopy study of the relationship between herpes gestationis and polymorphic eruption of pregnancy. Br J Dermatol 108:147–151

    Article  PubMed  CAS  Google Scholar 

  38. Kasp-Grochowska E, Beck J, Holmes RC et al (1984) The role of circulating immune complexes in the aetiology of polymorphic eruption of pregnancy. Arch Dermatol Res 276:71–73

    Article  PubMed  CAS  Google Scholar 

  39. Kroumpouzos G, Cohen LM (2001) Dermatoses of pregnancy. J Am Acad Dermatol 45:1–19; quiz 19–22

    Article  PubMed  CAS  Google Scholar 

  40. Kroumpouzos G, Cohen LM (2003) Specific dermatoses of pregnancy: an evidence-based systematic review. Am J Obstet Gynecol 188:1083–1092

    Article  PubMed  Google Scholar 

  41. Lawley TJ, Stingl G, Katz SI (1978) Fetal and maternal risk factors in herpes gestationis. Arch Dermatol 114:552–555

    Article  PubMed  CAS  Google Scholar 

  42. Lawley TJ, Hertz KC, Wade TR et al (1979) Pruritic urticarial papules and plaques of pregnancy. JAMA 241:1696–1699

    Article  PubMed  CAS  Google Scholar 

  43. Murray JC (1990) Pregnancy and the skin. Dermatol Clin 8:327–334

    PubMed  CAS  Google Scholar 

  44. Nelson JL, Furst DE, Maloney S et al (1998) Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Lancet 351:559–562

    Article  PubMed  CAS  Google Scholar 

  45. Normand F, Armingaud P, Esteve E (2001) Dyshidrosis and acral purpura during polymorphic dermatitis in pregnancy: 2 cases. Ann Dermatol Venereol 128:531–533

    PubMed  CAS  Google Scholar 

  46. Nurse DS (1968) Prurigo of pregnancy. Australas J Dermatol 9:258–267

    Article  PubMed  CAS  Google Scholar 

  47. Pauwels C, Bucaille-Fleury L, Recanati G (1994) Pruritic urticarial papules and plaques of pregnancy: relationship to maternal weight gain and twin or triplet pregnancies. Arch Dermatol 130:801–802

    Article  PubMed  CAS  Google Scholar 

  48. Powell FC (1992) Parity, polypregnancy, paternity, and PUPPP. Arch Dermatol 128:1551

    Article  PubMed  CAS  Google Scholar 

  49. Regnier S, Fermand V, Levy P et al (2008) A case-control study of polymorphic eruption of pregnancy. J Am Acad Dermatol 58:63–67

    Article  PubMed  Google Scholar 

  50. Reyes H (1982) The enigma of intrahepatic cholestasis of pregnancy: lessons from Chile. Hepatology 2:87–96

    Article  PubMed  CAS  Google Scholar 

  51. Roger D, Vaillant L, Lorette G (1990) Pruritic urticarial papules and plaques of pregnancy are not related to maternal or fetal weight gain. Arch Dermatol 126:1517

    Article  PubMed  CAS  Google Scholar 

  52. Roger D, Vaillant L, Fignon A et al (1994) Specific pruritic diseases of pregnancy. A prospective study of 3192 pregnant women. Arch Dermatol 130:734–739

    Article  PubMed  CAS  Google Scholar 

  53. Sasseville D, Wilkinson RD, Schnader JY (1981) Dermatoses of pregnancy. Int J Dermatol 20:223–241

    Article  PubMed  CAS  Google Scholar 

  54. Schwartz RA, Hansen RC, Lynch PJ (1981) Pruritic urticarial papules and plaques of pregnancy. Cutis 27:425–426, 432

    PubMed  CAS  Google Scholar 

  55. Sherard GB 3rd, Atkinson SM Jr (2001) Focus on primary care: pruritic dermatological conditions in pregnancy. Obstet Gynecol Surv 56:427–432

    Article  PubMed  Google Scholar 

  56. Shornick JK (1998) Dermatoses of pregnancy. Semin Cutan Med Surg 17:172–181

    Article  PubMed  CAS  Google Scholar 

  57. Sodhi VK, Sausker WF (1988) Dermatoses of pregnancy. Am Fam Physician 37:131–138

    PubMed  CAS  Google Scholar 

  58. Tarocchi S, Carli P, Caproni M et al (1997) Polymorphic eruption of pregnancy. Int J Dermatol 36:448–450

    PubMed  CAS  Google Scholar 

  59. Trattner A, Ingber A, Sandbank M (1991) Antiepidermal cell surface antibodies in a patient with pruritic urticarial papules and plaques of pregnancy. J Am Acad Dermatol 24:306–308

    Article  PubMed  CAS  Google Scholar 

  60. Uhlin SR (1981) Pruritic urticarial papules and plaques of pregnancy. Involvement in mother and infant. Arch Dermatol 117:238–239

    Article  PubMed  CAS  Google Scholar 

  61. Vaughan Jones SA, Hern S, Nelson-Piercy C et al (1999) A prospective study of 200 women with dermatoses of pregnancy correlating clinical findings with hormonal and immunopatho-logical profiles. Br J Dermatol 141:71–81

    Article  PubMed  CAS  Google Scholar 

  62. Weiss R, Hull P (1992) Familial occurrence of pruritic urticarial papules and plaques of pregnancy. J Am Acad Dermatol 26:715–717

    Article  PubMed  CAS  Google Scholar 

  63. Winton GB, Lewis CW (1982) Dermatoses of pregnancy. J Am Acad Dermatol 6:977–998

    Article  PubMed  CAS  Google Scholar 

  64. Yancey KB, Hall R P, Lawley TJ (1984) Pruritic urticarial papules and plaques of pregnancy. Clinical experience in twenty-five patients. J Am Acad Dermatol 10:473–480

    Article  PubMed  CAS  Google Scholar 

  65. Zoberman E, Farmer ER (1981) Pruritic folliculitis of pregnancy. Arch Dermatol 117:20–22

    Article  PubMed  CAS  Google Scholar 

  66. Zurn A, Celebi CR, Bernard P et al (1992) A prospective immunofluorescence study of 111 cases of pruritic dermatoses of pregnancy: IgM anti-basement membrane zone antibodies as a novel finding. Br J Dermatol 126:474–478

    PubMed  CAS  Google Scholar 

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(2009). Pruritic Urticarial Papules and Plaques of Pregnancy. In: Obstetric Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-88399-9_18

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  • DOI: https://doi.org/10.1007/978-3-540-88399-9_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-88398-2

  • Online ISBN: 978-3-540-88399-9

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