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Accelerated Partial Breast Irradiation pp 151–172Cite as

An Overview of European Clinical Trials of APBI

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In the last two decades, there has been an increasing interest in Europe in treating selected patients with early-stage breast cancer with accelerated partial breast irradiation (APBI) using interstitial or intracavitary (MammoSite) brachytherapy. In this chapter, we give an overview of these European clinical trials of APBI, including their implications for optimal patient selection, target definition, treatment technique, and quality assurance. Finally, we will discuss the development and status of the new European multicentric Phase III APBI trial conducted by the Breast Cancer Working Group of the Groupe Européen de Curiethérapie—European Society for Therapeutic Radiology and Oncology (GEC-ESTRO).

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Author information

Authors and Affiliations

  1. Department of Radiotherapy, National Institute of Oncology, Ráth Gy. u. 7-9, Budapest, 1122, Hungary

    Csaba Polgár, Tibor Major & Katalin Lövey

  2. Department of Radiation Oncology, University Hospital Erlangen, Universitaetsstr. 27, Erlangen, 91054, Germany

    Vratislav Strnad & Oliver J. Ott

  3. Department of Radiation Oncology, University Hospital Schleswig-Holstein Campus Kiel, Arnold-Heller Str. 9, Kiel, 24105, Germany

    Peter Niehoff

  4. Interdisciplinary Brachytherapy Unit, University of Luebeck, Ratzeburger Allee 160, Luebeck, 23538, Germany

    György Kovács

Authors
  1. Csaba Polgár
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  2. Tibor Major
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  3. Vratislav Strnad
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  4. Peter Niehoff
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  5. Oliver J. Ott
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  6. Katalin Lövey
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  7. György Kovács
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Corresponding author

Correspondence to Csaba Polgár .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Tufts Medical Center, 750 Washington St., Boston, MA, 02111 NEMC 824, USA

    David E. Wazer

  2. Department of Radiation Oncology, Virginia Commonwealth University, 401 College Street, 980058, Richmond, VA, 23928, USA

    Douglas W. Arthur

  3. Department of Radiation Oncology, William Beaumont Hospital, 3601 W. Thirteen Mile Road, Royal Oak, MI, 48072, USA

    Frank A. Vicini

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© 2009 Springer-Verlag Berlin Heidelberg

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Polgár, C. et al. (2009). An Overview of European Clinical Trials of APBI. In: Wazer, D.E., Arthur, D.W., Vicini, F.A. (eds) Accelerated Partial Breast Irradiation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-88006-6_9

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  • DOI: https://doi.org/10.1007/978-3-540-88006-6_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-88005-9

  • Online ISBN: 978-3-540-88006-6

  • eBook Packages: MedicineMedicine (R0)

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