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Craniopharyngioma

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Book cover Pediatric CNS Tumors

Part of the book series: Pediatric Oncology ((PEDIATRICO))

Craniopharyngiomas are histologically benign neuroepithelial tumors that arise from rests of squamous-cell epithelium that remain along the path of the primitive craniopharyngeal duct and adeno-hypophysis. They frequently involve vital structures in the sellar region including the optic apparatus and the pituitary, and often lead to visual, endocrine, and mental disturbances. Despite their benign histology, the involvement of various neural structures in the suprasellar region makes the treatment and management of craniopharyngiomas difficult. There remains an ongoing controversy regarding optimal treatment of craniopharyngiomas. The debate revolves around the risks and benefits of attempted gross total resection as compared to subtotal resection or biopsy followed by other therapy such as external beam radiotherapy, radiosurgery, intracavitary radiation or sclerosis, and/or chemotherapy (Karavitaki et al. 2006).

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Authors and Affiliations

  1. Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143-0112, USA

    Michael E. Sughrue

  2. Department of Pediatrics, Division of Pediatric Endocrinology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA, 94143-0434, USA

    Robert H. Lustig

  3. Department of Radiation Oncology, Kaiser Santa Clara Medical Center, 3800 Homestead Road, Santa Clara, CA, 95051, USA

    Benjamin Fisch

  4. Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143-0112, USA

    Michael W. McDermott

Authors
  1. Michael E. Sughrue
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  2. Robert H. Lustig
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  3. Benjamin Fisch
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  4. Michael W. McDermott
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Corresponding author

Correspondence to Michael E. Sughrue .

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Editors and Affiliations

  1. Departments of Neurological Surgery and Pediatrics, Division of Pediatric Neurosurgery, University of California San Francisco, 505 Parnassus Avenue, Rm M779, San Francisco, CA, 94143-0112, USA

    Nalin Gupta

  2. Departments of Pediatrics and Neurological Surgery, Division of Hematology and Oncology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143-0106, USA

    Anuradha Banerjee

  3. Departments of Radiation Oncology and Neurological Surgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1600 Divisadero Street, San Francisco, CA, 94115-1708, USA

    Daphne Haas-Kogan

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Sughrue, M.E., Lustig, R.H., Fisch, B., McDermott, M.W. (2010). Craniopharyngioma. In: Gupta, N., Banerjee, A., Haas-Kogan, D. (eds) Pediatric CNS Tumors. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87979-4_7

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  • DOI: https://doi.org/10.1007/978-3-540-87979-4_7

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