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Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume S4))

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References

  1. Adams, M.D.; Celniker, S.E.; Holt, R.A.; Evan, C.A.; Gocayne, J.D.; et al.: The genome sequence of Drosophila melanogaster. Science, 287, 2185–2195 (2000)

    Article  PubMed  Google Scholar 

  2. Wood, V.; Gwilliam, R.; Rajandream, M.A.; Lyne, M.; Lyne, R.; et al.: The genome sequence of Schizosaccharomyces pombe. Nature, 415, 871–880 (2002)

    Article  PubMed  CAS  Google Scholar 

  3. Chase, D.; Feng, Y.; Hanshew, B.; Winkles, J.A.; Longo, D.L.; Ferris, D.K.: Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression. Biochem. J., 333, 655–660 (1998)

    PubMed  CAS  Google Scholar 

  4. Donohue, P.J.; Alberts, G.F.; Guo, Y.; Winkles, J.A.: Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J. Biol. Chem., 270, 10351–10357 (1995)

    Article  PubMed  CAS  Google Scholar 

  5. Holtrich, U.; Wolf, G.; Yuan, J.; Bereiter-Hahn, J.; Karn, T.; Weiler, M.; Kauselmann, G.; Rehli, M.; Andreesen, R.; Kaufmann, M.; Kuhl, D.; Strebhardt, K.: Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages. Oncogene, 19, 4832–4839 (2000)

    Article  PubMed  CAS  Google Scholar 

  6. Li, B.; Ouyang, B.; Pan, H.; Reissmann, P.T.; Slamon, D.J.; Arceci, R.; Lu, L.; Dai, W.: Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas. J. Biol. Chem., 271, 19402–19408 (1996)

    Article  PubMed  CAS  Google Scholar 

  7. Ouyang, B.; Li, W.; Pan, H.; Meadows, J.; Hoffmann, I.; Dai, W.: The physical association and phosphorylation of Cdc25C protein phosphatese by Prk. Oncogene, 18, 6029–6036 (1999)

    Article  PubMed  CAS  Google Scholar 

  8. Ouyang, B.; Pan, H.; Lu, L.; Li, J.; Stambrook, P.; Li, B.; Dai, W.: Human Prk is a conserved protein serine/threonine kinase involved in regulating M phase functions. J. Biol. Chem., 272, 28646–28651 (1997)

    Article  PubMed  CAS  Google Scholar 

  9. Kitada, K.; Johnson, A.L.; Johnston, L.H.; Sugino, A.: A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol. Cell. Biol., 13, 445–4457 (1993)

    Google Scholar 

  10. Chase, D.; Serafinas, C.; Ashcroft, N.; Kosinski, M.; Longo, D.; Ferris, D.K.; Golden, A.: The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans. Genesis, 26, 26–41 (2000)

    Article  PubMed  CAS  Google Scholar 

  11. Ouyang, B.; Wang, Y.; Wei, D.: Caenorhabditis elegans contains structural homologs of human prk and plk. DNA Seq., 10, 109–113 (1999)

    Article  PubMed  CAS  Google Scholar 

  12. Wilson, R.; Ainscough, R.; Anderson, K.; Baynes, C.; Berks, M.; Bonfield, J.; Burton, J.; Connell, M.; Copsey, T.; Cooper, J.; et al.: 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature, 368, 32–38 (1994)

    Article  PubMed  CAS  Google Scholar 

  13. Ohkura, H.; Hagan, I.M.; Glover, D.M.: The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells. Genes Dev., 9, 1059–1073 (1995)

    Article  PubMed  CAS  Google Scholar 

  14. Llamazares, S.; Moreira, A.; Tavares, A.; et al.: Polo encodes a protein kinase homolog required for mitosis in Drosophila. Genes Dev., 5, 2153–2165 (1991)

    Article  PubMed  CAS  Google Scholar 

  15. Holtrich, U.; Wolf, G.; Brauninger, A.; Karn, T.; Bohme, B.; Rubsamen-Waigmann, H.; Strebhardt, K.: Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. Proc. Natl. Acad. Sci. USA, 91, 1736–1740 (1994)

    Article  PubMed  CAS  Google Scholar 

  16. Hamanaka, R.; Maloid, S.; Smith, M.R.; O’Connell, C.D.; Longo, D.L.; Ferris, D.K.: Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase. Cell Growth Differ., 5, 249–257 (1994)

    PubMed  CAS  Google Scholar 

  17. Golsteyn, R.M.; Schultz, S.J.; Bartek, J.; Ziemiecki, A.; Ried, T.; Nigg, E.A.: Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5. J. Cell Sci., 107, 1509–1517 (1994)

    PubMed  CAS  Google Scholar 

  18. Lake, R.J.; Jelinek, W.R.: Cell cycle-and terminal differentiation-associated regulation of the mouse mRNA encoding a conserved mitotic protein kinase. Mol. Cell. Biol., 13, 7793–7801 (1993)

    PubMed  CAS  Google Scholar 

  19. Simmons, D.L.; Neel, B.G.; Stevens, R.; Evett, G.; Erikson, R.L.: Identification of an early-growth-response gene encoding a novel putative protein kinase. Mol. Cell. Biol., 12, 4164–4169 (1992)

    PubMed  CAS  Google Scholar 

  20. Clay, F.J.; McEwen, S.J.; Bertoncello, I.; Wilks, A.F.; Dunn, A.R.: Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila. Proc. Natl. Acad. Sci. USA, 90, 4882–4886 (1993)

    Article  PubMed  CAS  Google Scholar 

  21. Fode, C.; Motro, B.; Yousefi, S.; Heffernan, M.; Dennis, J.W.: Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation. Proc. Natl. Acad. Sci. USA., 91, 6388–6392 (1994)

    Article  PubMed  CAS  Google Scholar 

  22. Chase, D.; Golden, A.; Heidecker, G.; Ferris, D.K.: Caenorhabditis elegans contains a third polo-like kinase gene. DNA Seq., 11, 327–334 (2000)

    Article  PubMed  CAS  Google Scholar 

  23. Kauselmann, G.; Weiler, M.; Wulff, P.; Jessberger, S.; Konietzko, U.; Scafidi, J.; Staubli, U.; Bereiter-Hahn, J.; Strebhardt, K.; Kuhl, D.: The polo-like protein kinases Fnk and Snk associate with a Ca2+-and integrin-binding protein and are regulated dynamically with synaptic plasticity. EMBO J., 18, 5528–5539 (1999)

    Article  PubMed  CAS  Google Scholar 

  24. Rancati, G.; Crispo, V.; Lucchini, G.; Piatti, S.: Mad3/BubR1 phosphorylation during spindle checkpoint activation depends on both Polo and Aurora kinases in budding yeast. Cell Cycle, 4, 972–980 (2005)

    PubMed  CAS  Google Scholar 

  25. Yao, L.J.; Fan, H.Y.; Tong, C.; Chen, D.Y.; Schatten, H.; Sun, Q.Y.: Polo-like kinase-1 in porcine oocyte meiotic maturation, fertilization and early embryonic mitosis. Cell. Mol. Biol., 49, 399–405 (2003)

    PubMed  CAS  Google Scholar 

  26. Warnke, S.; Kemmler, S.; Hames, R.S.; Tsai, H.L.: Hoffmann-Rohrer, U.; Fry, A.M.; Hoffmann, I.: Polo-like kinase-2 is required for centriole duplication in mammalian cells. Curr. Biol., 14, 1200–1207 (2004)

    Article  PubMed  CAS  Google Scholar 

  27. Sumara, I.; Gimenez-Abian, J.F.; Gerlich, D.; Hirota, T.; Kraft, C.; de la Torre, C.; Ellenberg, J.; Peters, J.M.: Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr. Biol., 14, 1712–1722 (2004)

    Article  PubMed  CAS  Google Scholar 

  28. Ahonen, L.J.; Kallio, M.J.; Daum, J.R.; Bolton, M.; Manke, I.A.; Yaffe, M.B.; Stukenberg, P.T.; Gorbsky, G.J.: Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr. Biol., 15, 1078–1089 (2005)

    Article  PubMed  CAS  Google Scholar 

  29. Clarke, A.S.; Tang, T.T.; Ooi, D.L.; Orr-Weaver, T.L.: POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332. Dev. Cell, 8, 53–64 (2005)

    Article  PubMed  CAS  Google Scholar 

  30. Cheng, K.Y.; Lowe, E.D.; Sinclair, J.; Nigg, E.A.; Johnson, L.N.: The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. EMBO J., 22, 5757–5768 (2003)

    Article  PubMed  CAS  Google Scholar 

  31. Nishiyama, A.; Muraki, K.; Saito, M.; Ohsumi, K.; Kishimoto, T.; Ishikawa, F.: Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. EMBO J., 25, 575–584 (2006)

    Article  PubMed  CAS  Google Scholar 

  32. Ruan, Q.; Wang, Q.; Xie, S.; Fang, Y.; Darzynkiewicz, Z.; Guan, K.; Jhanwar-Uniyal, M.; Dai, W.: Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle. Exp. Cell Res., 294, 51–59 (2004)

    Article  PubMed  CAS  Google Scholar 

  33. MacIver, F.H.; Tanaka, K.; Robertson, A.M.; Hagan, I.M.: Physical and functional interactions between polo kinase and the spindle pole component Cut 12 regulate mitotic commitment in S. pombe. Genes Dev., 17, 1507–1523 (2003)

    Article  PubMed  CAS  Google Scholar 

  34. Nakajima, H.; Toyoshima-Morimoto, F.; Taniguchi, E.; Nishida, E.: Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J. Biol. Chem., 278, 25277–25280 (2003)

    Article  PubMed  CAS  Google Scholar 

  35. Tsvetkov, L.; Xu, X.; Li, J.; Stern, D.F.: Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J. Biol. Chem., 278, 8468–8475 (2003)

    Article  PubMed  CAS  Google Scholar 

  36. Ando, K.; Ozaki, T.; Yamamoto, H.; Furuya, K.; Hosoda, M.; Hayashi, S.; Fukuzawa, M.; Nakagawara, A.: Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation. J. Biol. Chem., 279, 25549–25561 (2004)

    Article  PubMed  CAS  Google Scholar 

  37. Eckerdt, F.; Yuan, J.; Saxena, K.; Martin, B.; Kappel, S.; Lindenau, C.; Kramer, A.; Naumann, S.; Daum, S.; Fischer, G.; Dikic, I.; Kaufmann, M.; Strebhardt, K.: Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. J. Biol. Chem., 280, 36575–36583 (2005)

    Article  PubMed  CAS  Google Scholar 

  38. Zhang, W.; Fletcher, L.; Muschel, R.J.: The role of polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation. J. Biol. Chem., 280, 42994–42999 (2005)

    Article  PubMed  CAS  Google Scholar 

  39. Mulvihill, D.P.; Hyams, J.S.: Cytokinetic actomyosin ring formation and septation in fission yeast are dependent on the full recruitment of the polo-like kinase PLO1 to the spindle pole body and a functional spindle assembly checkpoint. J. Cell Sci., 115, 3575–3586 (2002)

    Article  PubMed  CAS  Google Scholar 

  40. Reynolds, N.; Ohkura, H.: Polo boxes form a single functional domain that mediates interactions with multiple proteins in fission yeast polo kinase. J. Cell Sci., 116, 1377–1387 (2003)

    Article  PubMed  CAS  Google Scholar 

  41. Bachewich, C.; Thomas, D.Y.; Whiteway, M.: Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth. Mol. Biol. Cell, 14, 2163–2180 (2003)

    Article  PubMed  CAS  Google Scholar 

  42. Visintin, R.; Stegmeier, F.; Amon, A.: The role of the polo kinase Cdc5 in controlling Cdc 14 localization. Mol. Biol. Cell, 14, 4486–4498 (2003)

    Article  PubMed  CAS  Google Scholar 

  43. Fan, H.Y.; Tong, C.; Teng, C.B.; Lian, L.; Li, S.W.; Yang, Z.M.; Chen, D.Y.; Schatten, H.; Sun, Q.Y.: Characterization of polo-like kinase-1 in rat oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization, and cleavage. Mol. Reprod. Dev., 65, 318–329 (2003)

    Article  PubMed  CAS  Google Scholar 

  44. Petersen, J.; Hagan, I.M.: Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast. Nature, 435, 507–512 (2005)

    Article  PubMed  CAS  Google Scholar 

  45. Glover, D.M.: Polo kinase and progression through M phase in Drosophila: a perspective from the spindle poles. Oncogene, 24, 230–237 (2005)

    Article  PubMed  CAS  Google Scholar 

  46. Xie, S.; Xie, B.; Lee, M.Y.; Dai, W.: Regulation of cell cycle checkpoints by polo-like kinases. Oncogene, 24, 277–286 (2005)

    Article  PubMed  Google Scholar 

  47. Liu, X.; Erikson, R.L.: Polo-like kinase (Plk) 1 depletion induces apoptosis in cancer cells. Proc. Natl. Acad. Sci. USA., 100, 5789–5794 (2003)

    Article  PubMed  CAS  Google Scholar 

  48. Hansen, D.V.; Tung, J.J.; Jackson, P.K.: CaMKII and Polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proc. Natl. Acad. Sci. USA., 103, 608–613 (2006)

    Article  PubMed  CAS  Google Scholar 

  49. Lee, B.H.; Amon, A.: Role of polo-like kinase CDC5 in programming meiosis I chromosome segregation. Science, 300, 482–486 (2003)

    Article  PubMed  CAS  Google Scholar 

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(2009). Polo kinase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol S4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85701-3_5

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