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Pharmacology and Therapeutics of Cough pp 297–310Cite as

Clinical Cough III: Measuring the Cough Response in the Laboratory

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 187))

Abstract

As interest in clinical cough research grows, measurement of cough reflex sensitivity will assume an increasingly important role. With proper equipment and meticulous attention to methodological details, cough reflex sensitivity can be safely, accurately, and reproducibly determined. Such precise measurement allows the evaluation of the effect of pharmacological or nonpharmacological interventions on the sensitivity of the cough reflex, or the comparison of cough reflex sensitivity between different subject populations. In addition to the method, other vital components of optimal cough challenge testing include proper interpretation of data and appropriate selection of study populations.

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Author information

Authors and Affiliations

  1. Einstein Division/Montefiore Medical Center, 1825 Eastchester Road, New York, NY, 10461, USA

    P. V. Dicpinigaitis

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  1. P. V. Dicpinigaitis
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Editor information

Editors and Affiliations

  1. National Heart & Lung Institute, Imperial College, Dovehouse Street, London, SW3 6LY, UK

    Kian Fan Chung

  2. University of London, 116 Pepys Road, London, SW20 8NY, UK

    John Widdicombe

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Dicpinigaitis, P.V. (2009). Clinical Cough III: Measuring the Cough Response in the Laboratory. In: Chung, K.F., Widdicombe, J. (eds) Pharmacology and Therapeutics of Cough. Handbook of Experimental Pharmacology, vol 187. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79842-2_15

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