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Pathology of Coronary Artery Disease and Ischemic Heart Disease

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Abstract

Atherosclerotic coronary artery disease and acute coronary syndromes are a leading cause of mortality and morbidity all over the world. As a result of intensive investigation over decades, a detailed understanding of the pathophysiology of these conditions has resulted in advances in their therapeutics as well as prevention.

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References

  1. Fye WB (2005) A historical perspective on atherosclerosis and coronary artery disease. In Fuster V, Topol EJ, Nabel EG (eds). Atherosclerosis and Coronary Artery Disease, 2nd edn. Lippicott, Williams and Wilkins, Philadelphia, pp. 1–44.

    Google Scholar 

  2. Fuster V, Moreno PR, Fayad ZA, Corti R, Badimon JJ (2005) Atherothrombosis and high-risk plaque: part I: evolving concepts. J Am Coll Cardiol 46(6):937–954.

    Article  PubMed  Google Scholar 

  3. Fukuda K, Yuasa S (2006) Stem cells as a source of regenerating cardiomyocytes. Circulation Res 98:1002.

    Article  PubMed  Google Scholar 

  4. Stary HC, Chandler AB, Dinsmore RE et al. (1995) A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association Circulation. 92:1355–1374.

    PubMed  CAS  Google Scholar 

  5. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20:1262–1275.

    PubMed  CAS  Google Scholar 

  6. Lafont A (2003) Basic aspects of plaque vulnerability. Heart 89:1262–1267.

    Article  PubMed  Google Scholar 

  7. Kereiakes DJ (2003) The Emperor’s clothes. In search of the vulnerable plaque. Circulation 107:2076.

    Article  PubMed  Google Scholar 

  8. Kolodgie FD, Burke AP, Farb A et al. (2001) The thin-cap fibroatheroma: a type of vulnerable plaque. The major precursor lesion to acute coronary syndromes. Current Opin Cardiol 16:285–292.

    Article  CAS  Google Scholar 

  9. Libby P (1995) Molecular bases of the acute coronary syndromes. Circulation 91:2844–2850.

    PubMed  CAS  Google Scholar 

  10. Schaar JA, Muller JE, Falk E et al. (2004) Terminology for high-risk and vulnerable coronary artery plaques. Report of a Meeting on the Vulnerable Plaque, June 17 and 18, 2003, Santorini, Greece. Eur Heart J 25:1077–1082.

    Article  PubMed  Google Scholar 

  11. Sangiorgi G, Taylor AJ, Farb A et al. (1999) Pathology of postpercutaneous transluminal coronary angioplasty remodeling in human coronary arteries. Am Heart J 138(4):681–687.

    Article  PubMed  CAS  Google Scholar 

  12. Farb A, Sangiorgi G, Carter AJ et al. (1999) Pathology of acute and chronic coronary stenting in humans. Circulation 99:44–52.

    PubMed  CAS  Google Scholar 

  13. Motwani JG, Topol EJ (1998) Aortocoronary saphenous vein graft disease. pathogenesis, predisposition, and prevention. Circulation 97:916–931.

    PubMed  CAS  Google Scholar 

  14. Buja LM (2005) Myocardial ischemia and reperfusion injury. Cardiovasc Pathol 14(4):170–175.

    Article  PubMed  CAS  Google Scholar 

  15. Weisman HF, Bush DE, Mannisi JA, Weisfeldt ML, Healy B (1988) Cellular mechanisms of myocardial infarct expansion. Circulation 78:186–201.

    PubMed  CAS  Google Scholar 

  16. Brown TA (2001) Hibernating myocardium. Am J Crit Care 10(2):84–91.

    PubMed  CAS  Google Scholar 

  17. Reimer KA, Vander Heide RS, Richard VJ (1993) Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models. Am J Cardiol. 72(19):13G–21G.

    Article  PubMed  CAS  Google Scholar 

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© 2009 Springer-Verlag Berlin Heidelberg

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Kini, U., Mullick, S. (2009). Pathology of Coronary Artery Disease and Ischemic Heart Disease. In: Movahed, A., Gnanasegaran, G., Buscombe, J., Hall, M. (eds) Integrating Cardiology for Nuclear Medicine Physicians. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-78674-0_3

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  • DOI: https://doi.org/10.1007/978-3-540-78674-0_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-78673-3

  • Online ISBN: 978-3-540-78674-0

  • eBook Packages: MedicineMedicine (R0)

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