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Yearbook of Intensive Care and Emergency Medicine pp 121–136Cite as

Pediatric Cardiopulmonary Arrest and Resuscitation

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Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2008))

Abstract

In this chapter we will briefly review the current state-of-the-art in pediatric cardiac arrest: Epidemiology, the four phases of cardiac arrest, mechanisms of blood flow during cardiopulmonary resuscitation (CPR), interventions, post-arrest supportive care, special resuscitation circumstances (pediatric ventricular fibrillation [VF], post-congenital heart surgery, extracorporeal membrane oxygenation [ECMO]- CPR), and innovative implementation of training programs.

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References

  1. Young KD, Seidel JS (1999) Pediatric cardiopulmonary resuscitation: a collective review. Ann Emerg Med 33:195–205

    Article  CAS  PubMed  Google Scholar 

  2. Donoghue AJ, Nadkarni VM, Elliott M, Durbin D (2006) Effect of hospital characteristics on outcomes from pediatric cardiopulmonary resuscitation: a report from the national registry of cardiopulmonary resuscitation. Pediatrics 118:995–1001

    Article  PubMed  Google Scholar 

  3. Nadkarni VM, Larkin GL, Peberdy MA, et al (2006) First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults. JAMA 295:50–57

    Article  CAS  PubMed  Google Scholar 

  4. Berg MD, Samson RA, Meyer RJ, Clark LL, Valenzuela TD, Berg RA (2005) Pediatric defibrillation doses often fail to terminate prolonged out-of-hospital ventricular fibrillation in children. Resuscitation 67:63–67

    Article  PubMed  Google Scholar 

  5. Dieckmann RA, Vardis R (1995) High-dose epinephrine in pediatric out-of-hospital cardiopulmonary arrest. Pediatrics 95:901–913

    CAS  PubMed  Google Scholar 

  6. Gerein RB, Osmond MH, Stiell IG, Nesbitt LP, Burns S (2006) What are the etiology and epidemiology of out-of-hospital pediatric cardiopulmonary arrest in Ontario, Canada? Acad Emerg Med 13:653–658

    Article  PubMed  Google Scholar 

  7. Kuisma M, Suominen P, Korpela R (1995) Paediatric out-of-hospital cardiac arrests — epidemiology and outcome. Resuscitation 30:141–150

    Article  CAS  PubMed  Google Scholar 

  8. Lopez-Herce J, Garcia C, Dominguez P, et al (2005) Outcome of out-of-hospital cardiorespiratory arrest in children. Pediatr Emerg Care 21:807–815

    Article  PubMed  Google Scholar 

  9. Schindler MB, Bohn D, Cox PN, et al (1996) Outcome of out-of-hospital cardiac or respiratory arrest in children. N Engl J Med 335:1473–1479

    Article  CAS  PubMed  Google Scholar 

  10. Sirbaugh PE, Pepe PE, Shook JE, et al (1999) A prospective, population-based study of the demographics, epidemiology, management, and outcome of out-of-hospital pediatric cardiopulmonary arrest. Ann Emerg Med 33:174–184

    Article  CAS  PubMed  Google Scholar 

  11. Suominen P, Korpela R, Kuisma M, Silfvast T, Olkkola KT (1997) Paediatric cardiac arrest and resuscitation provided by physician-staffed emergency care units. Acta Anaesthesiol Scand 41:260–265

    Article  CAS  PubMed  Google Scholar 

  12. Suominen P, Rasanen J, Kivioja A (1998) Efficacy of cardiopulmonary resuscitation in pulseless paediatric trauma patients. Resuscitation 36:9–13

    Article  CAS  PubMed  Google Scholar 

  13. Tunstall-Pedoe H, Bailey L, Chamberlain DA, Marsden AK, Ward ME, Zideman DA (1992) Survey of 3765 cardiopulmonary resuscitations in British hospitals (the BRESUS Study): methods and overall results. BMJ 304:1347–1351

    Article  CAS  PubMed  Google Scholar 

  14. Chamnanvanakij S, Perlman JM (2000) Outcome following cardiopulmonary resuscitation in the neonate requiring ventilatory assistance. Resuscitation 45:173–180

    Article  CAS  PubMed  Google Scholar 

  15. Hintz SR, Benitz WE, Colby CE, Sheehan AM, Rycus P, Van Meurs KP (2005) Utilization and outcomes of neonatal cardiac extracorporeal life support: 1996–2000. Pediatr Crit Care Med 6:33–38

    Article  PubMed  Google Scholar 

  16. Meaney PA, Nadkarni VM, Cook EF, et al (2006) Higher survival rates among younger patients after pediatric intensive care unit cardiac arrests. Pediatrics 118:2424–2433

    Article  PubMed  Google Scholar 

  17. Parra DA, Totapally BR, Zahn E, et al (2000) Outcome of cardiopulmonary resuscitation in a pediatric cardiac intensive care unit. Crit Care Med 28:3296–3300

    Article  CAS  PubMed  Google Scholar 

  18. Reis AG, Nadkarni V, Perondi MB, Grisi S, Berg RA (2002) A prospective investigation into the epidemiology of in-hospital pediatric cardiopulmonary resuscitation using the international Utstein reporting style. Pediatrics 109:200–209

    Article  PubMed  Google Scholar 

  19. Samson RA, Nadkarni VM, Meaney PA, Carey SM, Berg MD, Berg RA (2006) Outcomes of inhospital ventricular fibrillation in children. N Engl J Med 354:2328–2339

    Article  CAS  PubMed  Google Scholar 

  20. Slonim AD, Patel KM, Ruttimann UE, Pollack MM (1997) Cardiopulmonary resuscitation in pediatric intensive care units. Crit Care Med 25:1951–1955

    Article  CAS  PubMed  Google Scholar 

  21. Suominen P, Olkkola KT, Voipio V, Korpela R, Palo R, Rasanen J (2000) Utstein style reporting of in-hospital paediatric cardiopulmonary resuscitation. Resuscitation 45:17–25

    Article  CAS  PubMed  Google Scholar 

  22. Torres A Jr, Pickert CB, Firestone J, Walker WM, Fiser DH (1997) Long-term functional outcome of inpatient pediatric cardiopulmonary resuscitation. Pediatr Emerg Care 13:369–373

    Article  PubMed  Google Scholar 

  23. Zaritsky A, Nadkarni V, Getson P, Kuehl K (1987) CPR in children. Ann Emerg Med 16:1107–1111

    Article  CAS  PubMed  Google Scholar 

  24. Paradis NA, Martin GB, Rivers EP, et al (1990) Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation. JAMA 263:1106–1113

    Article  CAS  PubMed  Google Scholar 

  25. Lurie K, Zielinski T, McKnite S, Sukhum P (2000) Improving the efficiency of cardiopulmonary resuscitation with an inspiratory impedance threshold valve. Crit Care Med 28(11 suppl):N207–209

    Article  CAS  PubMed  Google Scholar 

  26. Lurie KG, Coffeen P, Shultz J, McKnite S, Detloff B, Mulligan K (1995) Improving active compression-decompression cardiopulmonary resuscitation with an inspiratory impedance valve. Circulation 91:1629–1632

    CAS  PubMed  Google Scholar 

  27. Yannopoulos D, Aufderheide TP, Gabrielli A, et al (2006) Clinical and hemodynamic comparison of 15:2 and 30:2 compression-to-ventilation ratios for cardiopulmonary resuscitation. Crit Care Med 34:1444–1449

    Article  PubMed  Google Scholar 

  28. Brilli RJ, Gibson R, Luria JW, et al (2007) Implementation of a medical emergency team in a large pediatric teaching hospital prevents respiratory and cardiopulmonary arrests outside the intensive care unit. Pediatr Crit Care Med 8:236–246

    Article  PubMed  Google Scholar 

  29. Tibballs J, Kinney S (2004) A prospective before-and-after trial of a medical emergency team. Med J Aust 180:308

    PubMed  Google Scholar 

  30. Laurent I, Monchi M, Chiche JD, et al (2002) Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest. J Am Coll Cardiol 40:2110–2116

    Article  PubMed  Google Scholar 

  31. Hallstrom AP, Cobb LA, Johnson E, Copass MK (2003) Dispatcher assisted CPR: implementation and potential benefit. A 12-year study. Resuscitation 57:123–129

    Article  PubMed  Google Scholar 

  32. Berg RA, Hilwig RW, Kern KB, Ewy GA (2000) “Bystander” chest compressions and assisted ventilation independently improve outcome from piglet asphyxial pulseless “cardiac arrest”. Circulation 101:1743–1

    CAS  PubMed  Google Scholar 

  33. Idris AH, Staples ED, O’Brien DJ, et al (1994) Effect of ventilation on acid-base balance and oxygenation in low blood-flow states. Crit Care Med 22:1827–1834

    Article  CAS  PubMed  Google Scholar 

  34. Kinney SB, Tibballs J (2000) An analysis of the efficacy of bag-valve-mask ventilation and chest compression during different compression-ventilation ratios in manikin-simulated paediatric resuscitation. Resuscitation 43:115–120

    Article  CAS  PubMed  Google Scholar 

  35. Srikantan SK, Berg RA, Cox T, Tice L, Nadkarni VM (2005) Effect of one-rescuer compression/ ventilation ratios on cardiopulmonary resuscitation in infant, pediatric, and adult manikins. Pediatr Crit Care Med 6:293–297

    Article  PubMed  Google Scholar 

  36. Brown CG, Martin DR, Pepe PE, et al (1992) A comparison of standard-dose and high-dose epinephrine in cardiac arrest outside the hospital. The Multicenter High-Dose Epinephrine Study Group. N Engl J Med 327:1051–1055

    CAS  PubMed  Google Scholar 

  37. Lindner KH, Ahnefeld FW, Bowdler IM (1991) Comparison of different doses of epinephrine on myocardial perfusion and resuscitation success during cardiopulmonary resuscitation in a pig model. Am J Emerg Med 9:27–31

    Article  CAS  PubMed  Google Scholar 

  38. Callaham M, Madsen C, Barton C, Saunders C, Daley M, Pointer J (1992) A randomized clinical trial of high-dose epinephrine and norepinephrine versus standard-dose epinephrine in prehospital cardiac arrest. JAMA 268:2667–2672

    Article  CAS  PubMed  Google Scholar 

  39. Behringer W, Kittler H, Sterz F, et al (1998) Cumulative epinephrine dose during cardiopulmonary resuscitation and neurologic outcome. Ann Intern Med 129:450–456

    CAS  PubMed  Google Scholar 

  40. Perondi MB, Reis AG, Paiva EF, Nadkarni VM, Berg RA (2004) A comparison of high-dose and standard-dose epinephrine in children with cardiac arrest. N Engl J Med 350:1722–1730

    Article  CAS  PubMed  Google Scholar 

  41. Hypothermia After Cardiac Arrest Study Group (2002) Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 346:549–556

    Article  Google Scholar 

  42. Bernard SA, Gray TW, Buist MD, et al (2002) Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 346:557–563

    Article  PubMed  Google Scholar 

  43. Hickey RW, Kochanek PM, Ferimer H, Graham SH, Safar P (2000) Hypothermia and hyperthermia in children after resuscitation from cardiac arrest. Pediatrics 106:118–122

    Article  CAS  PubMed  Google Scholar 

  44. Gluckman PD, Wyatt JS, Azzopardi D, et al (2005) Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 365: 663–670

    PubMed  Google Scholar 

  45. Shankaran S, Laptook A, Wright LL, et al (2002) Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants. Pediatrics 110:377–385

    Article  PubMed  Google Scholar 

  46. Hoffman TM, Wernovsky G, Atz AM, et al (2003) Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation 107:996–1002

    Article  CAS  PubMed  Google Scholar 

  47. Innes PA, Frazer RS, Booker PD, et al (1994) Comparison of the haemodynamic effects of dobutamine with enoximone after open heart surgery in small children. Br J Anaesth 72: 77–81

    Article  CAS  PubMed  Google Scholar 

  48. Laitinen P, Happonen JM, Sairanen H, Peltola K, Rautiainen P (1999) Amrinone versus dopamine and nitroglycerin in neonates after arterial switch operation for transposition of the great arteries. J Cardiothorac Vasc Anesth 13:186–190

    Article  CAS  PubMed  Google Scholar 

  49. Laitinen P, Happonen JM, Sairanen H, et al (1997) Amrinone versus dopamine-nitroglycerin after reconstructive surgery for complete atrioventricular septal defect. J Cardiothorac Vasc Anesth 11:870–874

    Article  CAS  PubMed  Google Scholar 

  50. Abdallah I, Shawky H (2003) A randomised controlled trial comparing milrinone and epinephrine as inotropes in paediatric patients undergoing total correction of Tetralogy of Fallot. Egyptian Journal of Anaesthesia 19:323–329

    CAS  Google Scholar 

  51. Ceneviva G, Paschall JA, Maffei F, Carcillo JA (1998) Hemodynamic support in fluid-refractory pediatric septic shock. Pediatrics 102:e19

    Article  CAS  PubMed  Google Scholar 

  52. Langhelle A, Tyvold SS, Lexow K, Hapnes SA, Sunde K, Steen PA (2003) In-hospital factors associated with improved outcome after out-of-hospital cardiac arrest. A comparison between four regions in Norway. Resuscitation 56:247–263

    Article  CAS  PubMed  Google Scholar 

  53. Berger PB (2005) A glucose-insulin-potassium infusion did not reduce mortality, cardiac arrest, or cardiogenic shock after acute MI. ACP J Club 143:4–5

    Google Scholar 

  54. Nishisaki A, Sullivan J 3rd, Steger B, et al (2007) Retrospective analysis of the prognostic value of electroencephalography patterns obtained in pediatric in-hospital cardiac arrest survivors during three years. Pediatr Crit Care Med 8:10–17

    Article  PubMed  Google Scholar 

  55. Schellhammer F, Heindel W, Haupt WF, Landwehr P, Lackner K (1998) Somatosensory evoked potentials: a simple neurophysiological monitoring technique in supra-aortal balloon test occlusions. Eur Radiol 8:1586–1589

    Article  CAS  PubMed  Google Scholar 

  56. Piazza O, Cotena S, Esposito G, De Robertis E, Tufano R (2005) S100B is a sensitive but not specific prognostic index in comatose patients after cardiac arrest. Minerva Chir 60:477–480

    CAS  PubMed  Google Scholar 

  57. Smith BT, Rea TD, Eisenberg MS (2006) Ventricular fibrillation in pediatric cardiac arrest. Acad Emerg Med 13:525–529

    Article  PubMed  Google Scholar 

  58. Appleton GO, Cummins RO, Larson MP, Graves JR (1995) CPR and the single rescuer: at what age should you “call first” rather than “call fast”? Ann Emerg Med 25:492–494

    Article  CAS  PubMed  Google Scholar 

  59. Graf WD, Cummings P, Quan L, Brutocao D (1995) Predicting outcome in pediatric submersion victims. Ann Emerg Med 26:312–319

    Article  CAS  PubMed  Google Scholar 

  60. Caffrey SL, Willoughby PJ, Pepe PE, Becker LB (2002) Public use of automated external defibrillators. N Engl J Med 347:1242–1247

    Article  PubMed  Google Scholar 

  61. Valenzuela TD, Roe DJ, Nichol G, Clark LL, Spaite DW, Hardman RG (2000) Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. N Engl J Med 343: 1206–1209

    Article  CAS  PubMed  Google Scholar 

  62. Thiagarajan RR, Laussen PC, Rycus PT, Bartlett RH, Bratton SL (2007) Extracorporeal membrane oxygenation to aid cardiopulmonary resuscitation in infants and children. Circulation 116:1693–1700

    Article  PubMed  Google Scholar 

  63. Dalton HJ, Siewers RD, Fuhrman BP, et al (1993) Extracorporeal membrane oxygenation for cardiac rescue in children with severe myocardial dysfunction. Crit Care Med 21:1020–1028

    Article  CAS  PubMed  Google Scholar 

  64. del Nido PJ, Dalton HJ, Thompson AE, Siewers RD (1992) Extracorporeal membrane oxygenator rescue in children during cardiac arrest after cardiac surgery. Circulation 86(suppl): II300–II304

    PubMed  Google Scholar 

  65. Tecklenburg FW, Thomas NJ, Webb SA, Case C, Habib DM (1997) Pediatric ECMO for severe quinidine cardiotoxicity. Pediatr Emerg Care 13:111–113

    Article  CAS  PubMed  Google Scholar 

  66. Thalmann M, Trampitsch E, Haberfellner N, Eisendle E, Kraschl R, Kobinia G (2001) Resuscitation in near drowning with extracorporeal membrane oxygenation. Ann Thorac Surg 72: 607–608

    Article  CAS  PubMed  Google Scholar 

  67. Morris MC, Wernovsky G, Nadkarni VM (2004) Survival outcomes after extracorporeal cardiopulmonary resuscitation instituted during active chest compressions following refractory in-hospital pediatric cardiac arrest. Pediatr Crit Care Med 5:440–446

    Article  PubMed  Google Scholar 

  68. Abella BS, Alvarado JP, Myklebust H, et al (2005) Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA 293:305–310

    Article  CAS  PubMed  Google Scholar 

  69. Edelson DP, Abella BS, Kramer-Johansen J, et al (2006) Effects of compression depth and preshock pauses predict defibrillation failure during cardiac arrest. Resuscitation 71:137–145

    Article  PubMed  Google Scholar 

  70. Sunde K, Pytte M, Jacobsen D, et al (2007) Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest. Resuscitation 73:29–39

    Article  PubMed  Google Scholar 

  71. Stross JK (1983) Maintaining competency in advanced cardiac life support skills. JAMA 249:3339–3341

    Article  CAS  PubMed  Google Scholar 

  72. Grenvik A, Schaefer JJ 3rd, DeVita MA, Rogers P (2004) New aspects on critical care medicine training. Curr Opin Crit Care 10:233–237

    Article  PubMed  Google Scholar 

  73. DeVita MA, Schaefer J, Lutz J, Dongilli T, Wang H (2004) Improving medical crisis team performance. Crit Care Med 32(suppl):S61–65

    Article  PubMed  Google Scholar 

  74. Hunt EA, Hohenhaus SM, Luo X, Frush KS (2006) Simulation of pediatric trauma stabilization in 35 North Carolina emergency departments: identification of targets for performance improvement. Pediatrics 117:641–648

    Article  PubMed  Google Scholar 

  75. Donoghue AJ, Nadkarni V, Berg RA, et al (2005) Out-of-hospital pediatric cardiac arrest: an epidemiologic review and assessment of current knowledge. Ann Emerg Med 46:512–522

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Anesthesia and Critical Care Medicine, The Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA

    A. Topjian & V. M. Nadkarni

  2. Department of Pediatrics, University of Arizona School of Medicine, 1501 N Campbell Avenue, Tucson, AZ, 85724, USA

    R. A. Berg

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  1. A. Topjian
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  2. R. A. Berg
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  3. V. M. Nadkarni
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Topjian, A., Berg, R.A., Nadkarni, V.M. (2008). Pediatric Cardiopulmonary Arrest and Resuscitation. In: Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2008. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77290-3_12

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  • DOI: https://doi.org/10.1007/978-3-540-77290-3_12

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