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Anatomic Basis of Tumor Surgery pp 483–547Cite as

Liver, Biliary Tree, and Gallbladder

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Abstract

Surgical resection remains the mainstay therapy for primary cancer of the liver and for most of the metastatic disease affecting this organ. There is a renewed interest in operative approaches to the liver mainly with regard to great developments in staging (imaging technique) and the availability of complex surgical strategies, and predictability of hepatic functional tolerance. At present, the 5-year survival rate following successful resection of metastatic colorectal cancer and hepatocellular carcinoma ranges from 40% to 60%, and the operative mortality after resection is less than 5%.

An additional tool aside from resection is the delivery of regional therapy via hepatic artery infusions of chemotherapeutic agents; the latter strategy was at its peak early this decade and was indicated in patients with unresectable metastatic col-orectal cancer to the liver. Presently, the use of this strategy has declined as systemic chemotherapeutic agents have become more effective against this disease.

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Author information

Authors and Affiliations

  1. Department of Surgery, Division of General and GI Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA

    Juan M. Sarmiento (Assistant Professor of Surgery)

  2. Department of Surgery, Division of General and GI Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA

    John R. Galloway (Professor of Surgery, Director, Medical Director of Transplant and Surgical Intensive Care Unit, Associate Section Chief for Critical Care)

  3. Nutritional Metabolic Services, Emory University Hospital, Atlanta, GA, 30322, USA

    John R. Galloway (Professor of Surgery, Director, Medical Director of Transplant and Surgical Intensive Care Unit, Associate Section Chief for Critical Care)

  4. Emory University Hospital, 1364 Clifton Road NE, Suite H-122, Atlanta, GA, 30322, USA

    John R. Galloway (Professor of Surgery, Director, Medical Director of Transplant and Surgical Intensive Care Unit, Associate Section Chief for Critical Care)

  5. Nutrition and Metabolic Support, Emory University Hospital, Atlanta, GA, 30322, USA

    John R. Galloway (Professor of Surgery, Director, Medical Director of Transplant and Surgical Intensive Care Unit, Associate Section Chief for Critical Care)

  6. Georgia Surgical Associates, 5667 Peachtree Dunwoody Road NE, Suite 170, Atlanta, GA, 30342, USA

    John R. Galloway (Professor of Surgery, Director, Medical Director of Transplant and Surgical Intensive Care Unit, Associate Section Chief for Critical Care)

  7. Division of Surgical Oncology, Department of Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA

    George W. Daneker (Former Assistant Professor)

Authors
  1. Juan M. Sarmiento
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  2. John R. Galloway
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  3. George W. Daneker
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Corresponding author

Correspondence to Juan M. Sarmiento .

Editor information

Editors and Affiliations

  1. Department of Surgery, Emory University School of Medicine, 1365 Clifton Road, Atlanta, GA, 30322, USA

    William C. Wood

  2. Division of Surgical Oncology, Emory University School of Medicine, 1364 Clifton Road, Atlanta, GA, 30322, USA

    Charles A. Staley

  3. Centers for Surgical Anatomy and Technique, Emory University School of Medicine, 1462 Clifton Road, Atlanta, GA, 30322, USA

    John E. Skandalakis

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© 2010 Springer-Verlag Berlin Heidelberg

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Sarmiento, J.M., Galloway, J.R., Daneker, G.W. (2010). Liver, Biliary Tree, and Gallbladder. In: Wood, W.C., Staley, C.A., Skandalakis, J.E. (eds) Anatomic Basis of Tumor Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74177-0_11

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  • DOI: https://doi.org/10.1007/978-3-540-74177-0_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74176-3

  • Online ISBN: 978-3-540-74177-0

  • eBook Packages: MedicineMedicine (R0)

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