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Oncologic and Cardiologic PET/CT-Diagnosis pp 687–719Cite as

Cardiac PET and PET/CT

the Situation in the USA

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Abstract

Positron emission tomography has broadened the scope of non-invasive approaches to the study of the human cardiovascular system and for the detection of cardiac disease. Not only is it quantitative and can measure functional processes in absolute units, it also reaches beyond tissue perfusion and fuel substrate delivery. It affords delineation of downstream processes, including substrate metabolism and regulatory mechanisms, as well as biological events at the cellular and molecular level. Combined with computed tomography, PET adds functional information to structurally defined alterations of the cardiovascular system as delineated with CT. Conversely, CT images of the cardiovascular anatomy serve as a map for localization of spatially confi ned molecular and cellular events uncovered with PET. This chapter examines the current state of cardiac PET and PET/CT and how combined structure-function imaging contributes to and refi nes the characterization of cardiovascular disease. It focuses on those areas of greatest clinical impact, but also explores emerging approaches of future clinical value.

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Editors and Affiliations

  1. Diagnostisch Therapeutisches Zentrum am Frankfurter Tor, Kadiner Strasse 23, 10243, Berlin, Germany

    Wolfgang Mohnike MD (Professor) (Professor)

  2. Klinik für Nuklearmedizin und Zentrum der Radiologie, Klinikum der J. W. Goethe-Universität, Theodor-Stern-Kai 7, 60950, Frankfurt/Main, Germany

    Gustav Hör MD (Professor) (Professor)

  3. Department of Molecular and Medical Pharmacology, David Greffen School of Medicine at UCLA, University of California at Los Angeles, 650 Charles E. Young Drive South, Los Angeles, CA, 90095, USA

    Heinrich R. Schelbert MD, PhD (Gerorge V. Taplin Professor) (Gerorge V. Taplin Professor)

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(2008). Cardiac PET and PET/CT. In: Mohnike, W., Hör, G., Schelbert, H.R. (eds) Oncologic and Cardiologic PET/CT-Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74091-9_16

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