Abstract
Mitochondrial gene expression in the acellular slime mold Physarum polycephalum requires a diverse array of RNA editing events. Virtually all transcripts encoded in the organelle are subject to changes at the RNA level, including both mRNAs and stable RNAs. Roughly 500 editing events involving nucleotide insertion or deletion have been confirmed thus far; these occur co-transcriptionally. Base changes also occur in Physarum mitochondria, but these are much rarer and occur post-transcriptionally. This chapter focuses on the experimental approaches used to dissect the unique mechanism of insertion/deletion editing in Physarum mitochondria.
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Gott, J.M., Rhee, A.C. (2008). Insertion/Deletion Editing in Physarum polycephalum . In: Göringer, H.U. (eds) RNA Editing. Nucleic Acids and Molecular Biology, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73787-2_4
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DOI: https://doi.org/10.1007/978-3-540-73787-2_4
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