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Imaging of Remyelination and Neuronal Health

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Book cover Advances in multiple Sclerosis and Experimental Demyelinating Diseases

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 318))

Remyelination of axons that have been demyelinated due to multiple sclerosis (MS) may be a critical step in restoring the damaged axons and reversing the disease process. While it is possible to establish the presence of remyelination with microscopy of tissue samples, it is important to have noninvasive or minimally invasive methods to measure remyelination in living animals and humans. Such tools are critical to establishing the efficacy of agents purported to promote or enhance remyelination. This chapter reviews the technology of imaging of the brain, its application to MS, and the current state of imaging techniques for measuring remyelination and the health of the associated neurons in the setting of MS.

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Author information

Authors and Affiliations

  1. Department of Radiology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA

    B. J. Erickson

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  1. B. J. Erickson
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Editors and Affiliations

  1. Department of Neurology and Immunology, Mayo Clinic, College of Medicine, 200 First Street SW, Rochester, MN 55905, USA

    Moses Rodriguez

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© 2008 Springer-Verlag Berlin Heidelberg

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Erickson, B.J. (2008). Imaging of Remyelination and Neuronal Health. In: Rodriguez, M. (eds) Advances in multiple Sclerosis and Experimental Demyelinating Diseases. Current Topics in Microbiology and Immunology, vol 318. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73677-6_4

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