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BioPediatric Complexities of Growth and Development

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ALERT - Adverse Late Effects of Cancer Treatment

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Although increased survival and ultimately cure of cancer remains the primary goal of treatment, the quality of survival is largely dependent on the toxicities of treatment. In particular, the late effects of treatment, which may manifest months to years or even decades after therapy, have been a driving force in the evolution of the treatment of many curable cancers. Advances in radiation oncology and diagnostic radiology have led to more conformal treatments that spare adjacent normal structures, and chemotherapy regimens have likewise evolved. In addition, in many cancers, perhaps most notably Hodgkin lymphoma, favorable subsets of patients are now treated with decreased doses of chemotherapy and radiation while maintaining overall efficacy.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester Medical Center, 647, Rochester, NY, 14642, USA

    Louis S. Constine

  2. Radiation Oncology, Department of Radiation Oncology, The Methodist Hospital, 6565 Fannin St, 77030, Houston, TX, USA

    Arnold C. Paulino

  3. Radiation Oncology, Department of Radiation Oncology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 647, Rochester, NY, 14642, USA

    Sughosh Dhakal

Authors
  1. Arnold C. Paulino
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  2. Sughosh Dhakal
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  3. Louis S. Constine
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Corresponding author

Correspondence to Louis S. Constine .

Editor information

Editors and Affiliations

  1. Dept. Radiation Oncology, University of Rochester Medical Center James P. Wilmot Cancer Ctr., Rochester, New York, USA

    Philip Rubin

  2. Department of Radiation Oncology, University of Rochester Medical Center James P. Wilmot Cancer Ctr., Rochester, New York, USA

    Louis S. Constine

  3. Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina, USA

    Lawrence B. Marks

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© 2014 Springer-Verlag Berlin Heidelberg

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Paulino, A.C., Dhakal, S., Constine, L.S. (2014). BioPediatric Complexities of Growth and Development. In: Rubin, P., Constine, L., Marks, L. (eds) ALERT - Adverse Late Effects of Cancer Treatment. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72314-1_11

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  • DOI: https://doi.org/10.1007/978-3-540-72314-1_11

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-72313-4

  • Online ISBN: 978-3-540-72314-1

  • eBook Packages: MedicineMedicine (R0)

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