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Acute Leukemias pp 95–108Cite as

Molecular Biology and Genetics

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Part of the book series: Hematologic Malignancies ((HEMATOLOGIC))

Abstract

Acute lymphoblastic leukemia (ALL) is characterized by distinctive morphologic, cytogenetic, and molecular genetic features, some of which have important clinical implications for both diagnosis and predicting response to specific treatment regimens, while the role of others is yet to be defined. This chapter will describe the cytogenetic and molecular aberrations in ALL.

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  1. Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, USA

    Meir Wetzler

  2. Division of Hematology and Oncology Arthur G. James Cancer Hospital, Ohio State University, Columbus, OH, USA

    Kryzstof Mrózek

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Wetzler, M., Mrózek, K. (2008). Molecular Biology and Genetics. In: Acute Leukemias. Hematologic Malignancies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72304-2_6

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