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The Epidemiology of Glaucoma

  • Chapter
Book cover Glaucoma

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

  • Glaucoma is second to cataract as a leading cause of global blindness and is the leading cause of irreversible visual loss.

  • In 2002, 37 million individuals were blind worldwide, with glaucoma accounting for 12.3% of these individuals.

  • By the year 2020 it is estimated that there will be almost 80 million people in the world with open-angle glaucoma and angle-closure glaucoma. The majority of these individuals will have open-angle glaucoma. Of those with ACG, it is predicted that 70% will be women and 87% will be Asian.

  • Bilateral blindness from glaucoma is projected to affect 8.4 million individuals worldwide by 2010 and greater than 11 million by 2020. Globally, glaucoma is a significant cause of vision loss that disproportionately affects women and Asians.

  • Risk factors for open-angle glaucoma include increased age, African ethnicity, family history, increased intraocular pressure, myopia, and decreased corneal thickness.

  • Risk factors for angle closure glaucoma include Inuit and Asian ethnicity, hyperopia, female sex, shallow anterior chamber, short axial length, small corneal diameter, steep corneal curvature, shallow limbal chamber depth, and thick, relatively anteriorly positioned lens.

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References

  1. Arkell SM, Lightman DA, Sommer A (1987) The prevalence of glaucoma among Eskimos of northwest Alaska. Arch Ophthalmol 105:482–485

    PubMed  CAS  Google Scholar 

  2. Boland MV, Quigley HA (2007) Risk factors and openangle glaucoma: classification and application. J Glaucoma 16:406–418

    Article  PubMed  Google Scholar 

  3. Bonomi L, Marchini G, Marraffa M et al. (2000) Vascular risk factors for primary open angle glaucoma. The Egna-Neumarkt study. Ophthalmology 107:1287–1293

    Article  PubMed  CAS  Google Scholar 

  4. Buhrmann RR, Quigley HA, Barroy Y et al. (2000) Prevalence of glaucoma in a rural East African population. Invest Ophthalmol Vis Sci 41:40–48

    PubMed  CAS  Google Scholar 

  5. Caprioli J, Coleman AL (2008) Intraocular pressure fluctuation: a risk factor for visual field progression at low intraocular pressures in the Advanced Glaucoma Intervention Study. Ophthalmology 115(7):1123–1129

    Article  Google Scholar 

  6. Casson RJ, Newland HS, Muecke J et al. (2007) Gonioscopy findings and prevalence of occludable angles in a Burmese population: the Meiktila eye study. Br J Ophthalmol 91:856–859

    Article  PubMed  CAS  Google Scholar 

  7. Coleman AL, Gordon MO, Beiser JA et al. (2004) Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. Ophthalmology 138:684–685

    Google Scholar 

  8. Congdon NC, Qi Y, Quigley HA et al. (1997) Biometry and primary angle-closure glaucoma among Chinese, white and black populations. Ophthalmology 104:1489–1495

    PubMed  CAS  Google Scholar 

  9. Dandona L, Dandona R, Mandai P et al. (2000) Angle-closure glaucoma in an urban population in Southern India. Ophthalmology 107:1710–1716

    Article  PubMed  CAS  Google Scholar 

  10. de Voogd S, Ikram MK, Wolfs RC et al. (2005) Incidence of open-angle glaucoma in a general elderly population. The Rotterdam Study. Ophthalmology 112:1487–1493

    Article  PubMed  Google Scholar 

  11. Drance S, Anderson DR, Schulzer M et al. (2001) Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol 131:699–708

    Article  PubMed  CAS  Google Scholar 

  12. Duggal P, Klein AP, Lee KE et al. (2007) Identification of novel genetic loci for intraocular pressure: a genomewide scan of the Beaver Dam Eye Study. Arch Ophthalmol 125:74–79

    Article  PubMed  CAS  Google Scholar 

  13. European Glaucoma Prevention Study Group (2007) Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study. Ophthalmology 113:3–9

    Google Scholar 

  14. Eye Diseases Prevalence Research Group (2004) Prevalence of open-angle glaucoma among adults in the United States. Arch Ophthalmol 122:532–538

    Article  Google Scholar 

  15. Foster PJ, Baasanhu J, Alsbirk PH et al. (1996) Glaucoma in Mongolia. A population-based survey in Hovsgol province, northern Mongolia. Arch Ophthalmol 114:1235–1241

    PubMed  CAS  Google Scholar 

  16. Foster PJ, Oen FT, Machin D et al. (2000) The prevalence of glaucoma in Chinese residents of Singapore: a crosssectional population survey of the Tanjong Pagar district. Arch Ophthalmol 118:1105–1111

    PubMed  CAS  Google Scholar 

  17. Foster PJ, Johnson GJ (2001) Glaucoma in China: how big is the problem? Br J Ophthalmol 85:1277–1282

    Article  PubMed  CAS  Google Scholar 

  18. Friedman DS, Gazzard G, Foster P et al. (2003) Ultrasonographic biomicroscopy, Scheimpflug photography, and novel provocative tests in contralateral eyes of Chinese patients initially seen with acute angle closure. Arch Ophthalmol 121:633–642

    Article  PubMed  Google Scholar 

  19. Gordon MO, Beiser JA, Bandt JD et al. (2002) The ocular hypertension treatment study. Baseline factors that predict 20 the onset of primary open-angle glaucoma. Arch Ophthalmol 120:714–720

    PubMed  Google Scholar 

  20. He M, Foster PJ, Ge J et al. (2006) Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou. Invest Ophthalmol Vis Sci 47:2782–2788

    Article  PubMed  Google Scholar 

  21. He M, Foster PJ, Johnson GJ et al. (2006) Angle-closure in East Asian and European people. Different diseases? Eye 20:3–12

    Article  PubMed  CAS  Google Scholar 

  22. He M, Foster PJ, Ge J et al. (2006) Gonioscopy in adult Chinese: the Liwan Eye Study. Invest Ophthalmol Vis Sci 47:4772–4779

    Article  PubMed  Google Scholar 

  23. Hulsman CA, Vingerling JR, Hofman A et al. (2007) Blood pressure, arterial stiffness, and open-angle glaucoma. The Rotterdam Study. Arch Ophthalmol 125:805–812

    Article  PubMed  Google Scholar 

  24. Klein BE, Klein R, Sponsel WE et al. (1992) Prevalence of glaucoma. The Beaver Dam Eye Study. Ophthalmology 99:1499–1504

    PubMed  CAS  Google Scholar 

  25. Klein BE, Klein R, Meuer SM et al. (1993) Migraine headache and its association with open-angle glaucoma: the Beaver Dam Eye Study. Invest Ophthalmol Vis Sci 34:3024–3027

    PubMed  CAS  Google Scholar 

  26. Klein BD, Klein R, Jensen SC (1994) Open-angle glaucoma and older-onset diabetes. The Beaver Dam Eye Study. Ophthalmology 101:1173–1177

    PubMed  CAS  Google Scholar 

  27. Klein BE, Klein R, Lee KE (2004) Heritability of risk factors for primary open-angle glaucoma: the Beaver Dam Eye study. Invest Ophthalmol Vis Sci 45:59–62

    Article  PubMed  Google Scholar 

  28. Klein BE, Klein R, Knudtson MD (2005) Intraocular pressure and systemic blood pressure: longitudinal perspective: the Beaver Dam Eye Study. Br J Ophthalmol 89:284–287

    Article  PubMed  CAS  Google Scholar 

  29. Leske MC, Connell AM, Schachat AP et al. (1994) The Barbados Eye Study: prevalence of open angle glaucoma. Arch Ophthalmol 112:821–829

    PubMed  CAS  Google Scholar 

  30. Leske MC, Nemesure B, He Q et al. (2001) Patterns of open-angle glaucoma in the Barbados Family Study. Ophthalmology 108:1015–1022

    Article  PubMed  CAS  Google Scholar 

  31. Leske MC, Wu SY, Honkanen R et al. (2007) Nine-year incidence of open-angle glaucoma in the Barbados Eye Studies. Ophthalmology 114:1058–1064

    Article  PubMed  Google Scholar 

  32. Leske M, Wu SY, Hennis A et al. (2008) Risk factors for incident open-angle glaucoma: the Barbados Eye Studies. Ophthalmology 115:85–93

    Article  PubMed  Google Scholar 

  33. Mansberger SL, Romero FC, Smith NH et al. (2005) Causes of visual impairment and common eye problems in Northwest American Indians and Alaska Natives. Am J Public Health 95:881–886

    Article  PubMed  Google Scholar 

  34. Mason RP, Kosoko O, Wilson MR et al. (1989) National survey of the prevalence and risk factors of glaucoma in St. Lucia, West Indies. Part I. Prevalence findings. Ophthalmology 96:1363–1368

    PubMed  CAS  Google Scholar 

  35. Miglior S, Torri V, Zeyen T et al. (2007) Intercurrent factors associated with the development of open-angle glaucoma in the european glaucoma prevention study. Am J Ophthalmol 144:266–275

    Article  PubMed  Google Scholar 

  36. Mitchell P, Hourihan F, Sandbach J et al. (1999) The relationship between glaucoma and myopia. Ophthalmology 106:2010–2015

    Article  PubMed  CAS  Google Scholar 

  37. Mitchell P, Lee AJ, Rochtchina E et al. (2004) Open-angle glaucoma and systemic hypertension. The Blue Mountains Eye Study. J Glaucoma 3:319–326

    Article  Google Scholar 

  38. Mukesh BN, McCarty CA, Rait JL et al. (2002) Five-year incidence of open-angle glaucoma: the Vision Impairment Project. Ophthalmology 109:1047–5

    Article  PubMed  Google Scholar 

  39. Nouri-Mahdavi K, Hoffman D, Coleman AL et al. (2004) Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study. Ophthalmology 111:1627–1635

    Article  PubMed  Google Scholar 

  40. Ntim-Amponsah CT, Amoaku WM, Ofosu-Amaah S et al. (2004) Prevalence of glaucoma in an African population. Eye 18:491–497

    Article  PubMed  CAS  Google Scholar 

  41. Phelps CD, Corbett JJ (1985) Migraine and low-tension glaucoma. A case-control study. Invest Ophthalmol Vis Sci 26:1105–1108

    PubMed  CAS  Google Scholar 

  42. Quigley HA, Broman AT (2006) The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267

    Article  PubMed  CAS  Google Scholar 

  43. Quigley HA, Wesk SK, Rodrigues J et al. (2001) The prevalence of glaucoma in a population-based study of Hispanic subjects. Proyecto VER. Arch Ophthalmol 119:1819–1826

    PubMed  CAS  Google Scholar 

  44. Quigley HA, Friedman DS, Congdon NG (2003) Possible mechanisms of primary angle-closure and malignant glaucoma. J Glaucoma 12:167–180

    Article  PubMed  Google Scholar 

  45. Rein DB, Zhang P, Wirth KE et al. (2006) The economic burden of major adult visual disorders in the United States. Arch Ophthalmol 124:1754–1760

    Article  PubMed  Google Scholar 

  46. Resnikoff S, Pascolini D, Etyaale D et al. (2004) Global data on visual impairment in the year 2002. Bull World Health Organ 82:844–851

    PubMed  Google Scholar 

  47. Rotchford AP, Johnson GJ (2002) Glaucoma in Zulus: a population-based cross-sectional survey in a rural district in South Africa. Arch Ophthalmol 120:471–478

    PubMed  Google Scholar 

  48. Thomas R, Sekhar GC, Parikh R (2007) Primary angle closure glaucoma: a developing world perspective. Clin Exp Ophthalmol 35:374–378

    Article  Google Scholar 

  49. Tielsch JM, Sommer A, Katz J et al. (1991) Racial variations in the prevalence of primary open-angle glaucoma: the Baltimore eye survery. JAMA 266:369–374

    Article  PubMed  CAS  Google Scholar 

  50. Tielsch JM, Katz J, Sommer A, Quigley HA, Javitt JC (1994) Family history and risk of primary open angle glaucoma. The Baltimore eye survey. Arch Ophthalmol 112:69–73

    PubMed  CAS  Google Scholar 

  51. Tielsch JM, Katz J, Sommer A et al. (1995) Hypertension, perfusion pressure, and primary open-angle glaucoma. A population-based assessment. Arch Ophthalmol 113:216–221

    PubMed  CAS  Google Scholar 

  52. Topouzis F, Coleman AL, Harris A et al. (2006) Association of blood pressure status with the optic disk structure in non-glaucoma subjects: the Thessaloniki Eye Study. Ophthalmology 142:60–67

    Google Scholar 

  53. Varma R, Ying-Lai M, Francis BA et al. (2004) Prevalence of open-angle glaucoma and ocular hypertension in Latinos. The Los Angeles Latino Eye Study. Ophthalmology 111:1439–1448

    Article  PubMed  Google Scholar 

  54. Xu L, Want Y, Want S et al. (2007) High myopia and glaucoma susceptibility. The Beijing Eye Study. Ophthalmology 114:216–220

    Article  PubMed  Google Scholar 

  55. Wang JJ, Mitchell P, Smith W (1997) Is there an association between migraine headache and open angle glaucoma? Findings from the Blue Mountains Eye Study. Ophthalmology 104:1714–1719

    PubMed  CAS  Google Scholar 

  56. Wong TY, Klein BE, Klein R et al. (2003) Refractive errors, intraocular pressure, and glaucoma in a white population. Ophthalmology 110:211–217

    Article  PubMed  Google Scholar 

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Giangiacomo, A., Coleman, A.L. (2009). The Epidemiology of Glaucoma. In: Grehn, F., Stamper, R. (eds) Glaucoma. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69475-5_2

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  • DOI: https://doi.org/10.1007/978-3-540-69475-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69472-4

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