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Uveal Biopsy with 25-Gauge Vitrector: Work in Progress

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Book cover Vitreo-retinal Surgery

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

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  • Intraocular tumors are conventionally diagnosed with noninvasive techniques, namely, clinical characteristics, angiographic and ultrasonographic features.

  • Rarely, intraocular masses require histopathology to increase diagnostic yield.

  • Results from intraocular biopsy can lead to revision of the therapeutic plan.

  • A variety of techniques exist to obtain intraocular tissue, most commonly fine-needle aspiration biopsy (FNAB).

  • Vitrectomy-based biopsy techniques utilizing a 20-gauge aspiration cutter have been performed in an effort to increase the diagnostic yield compared to FNAB, but at the expense of increased complications.

  • Intraocular biopsy based on a 25-gauge aspiration cutter is explored, with the intent of providing the safety benefits of FNAB and the potential benefit of increased diagnostic yield of vitrectomy.

  • Biopsy with 25-gauge aspiration cutter can be performed for anterior segment and posterior segment indeterminate lesions.

  • Albeit with limited follow-up and small number of cases, biopsy with the 25-gauge aspiration cutter did yield adequate amounts of specimen for histopathologic diagnosis, with no significant complications.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada

    F. Altomare

  2. Department of Ophthalmology, St. Michael’s Hospital, Toronto, ON, Canada

    F. Altomare

  3. Department of Ocular Oncology Princess Margaret Hospital, University Health Network, Toronto, ON, Canada

    F. Altomare

Authors
  1. F. Altomare
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Editor information

Editors and Affiliations

  1. Eye Surgery Clinic, Santa Chiara Hospital, Via Roma, 67, 56100, Pisa, Italy

    Stanislao Rizzo MD (Professor and Chairman of Ophthalmology) (Professor and Chairman of Ophthalmology)

  2. Milano Retina Center, via Pietro Mascagni, 20, 20122, Milano, Italy

    Fabio Patelli MD

  3. University of Toronto, 23 Ivor Rd., North York, Ontario, M4N 2H3, Canada

    David R. Chow MD

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© 2009 Springer-Verlag Berlin Heidelberg

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Altomare, F. (2009). Uveal Biopsy with 25-Gauge Vitrector: Work in Progress. In: Rizzo, S., Patelli, F., Chow, D.R. (eds) Vitreo-retinal Surgery. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68586-9_16

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  • DOI: https://doi.org/10.1007/978-3-540-68586-9_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69461-8

  • Online ISBN: 978-3-540-68586-9

  • eBook Packages: MedicineMedicine (R0)

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