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Soft-Tissue Sarcomas

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Cancer in Adolescents and Young Adults

Part of the book series: Pediatric Oncology ((PEDIATRICO))

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References

  1. Bleyer WA, O’Leary M, Barr R, Ries LAG (eds) (2006) Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, including SEER Incidence and Survival, 1975–2000. National Cancer Institute, NIH Pub. No. 06-5767. Bethesda, MD 2006, pp 220

    Google Scholar 

  2. Wexler LH, Meyer WH, Helmann LJ. Rhabdomyosarcoma and the undifferentiated sarcomas. In Pizzo PA, Poplack DC (eds), Principles and Practice of Pediatric Oncology. 5th ed. Lippincott Williams & Wilkins, Philadelphia, pp 971–1001

    Google Scholar 

  3. Okcu MF, Hicks J, Merchant TE, et al: Nonrhabdomyosarcomatous soft tissue sarcomas. In Pizzo PA, Poplack DC (eds), Principles and Practice of Pediatric Oncology. 5th ed. Lippincott Williams & Wilkins, Philadelphia, 2006, pp 1033–1073

    Google Scholar 

  4. Bleyer WA, Tejeda H, Murphy SB, et al (1997) National cancer clinical trials: children have equal access; adolescents do not. J Adolesc Health 21:366–373

    Article  PubMed  CAS  Google Scholar 

  5. Bleyer A, Montello M, Budd T, Saxman S (2005) National survival trends of young adults with sarcoma: lack of progress is associated with lack of clinical trial participation. Cancer 103:1891–1897

    Article  PubMed  Google Scholar 

  6. Pappo AS, Shapiro DN, Crist WM, Maurer HM (1995) Biology and therapy of pediatric rhabdomyosarcoma. J Clin Oncol 13:2123–2139

    PubMed  CAS  Google Scholar 

  7. Newton WA, Gehan EA, Webber BL, et al (1995) Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification — an Intergroup Rhabdomyosarcoma Study. Cancer 70:1073–1085

    Article  Google Scholar 

  8. Borden EC, Baker LH, Bell RS, et al (2003) Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res 9:1941–1956

    PubMed  Google Scholar 

  9. Maurer HM, Beltangady M, Gehan EA, et al: The Intergroup Rhabdomyosarcoma Study I: a final report. Cancer 61:209–220, 1988

    Article  PubMed  CAS  Google Scholar 

  10. iHarmer MH: TNM Classification of pediatric tumors. Geneva, Switzerland, UICC International Union Against canser, 1982:23–28

    Google Scholar 

  11. Wunder JS, Healey JH, Davis AM, Brennan MF. A (2000) comparsion of staging systems for localized extremity soft tissue sarcoma. Cancer 88:2721–2730

    Article  PubMed  CAS  Google Scholar 

  12. Crist WM, Anderson JR, Meza JL, et al (2001) Intergroup Rhabdomyosarcoma Study-IV: results for patients with nonmetastatic disease. J Clin Oncol 19:3091–3102

    PubMed  CAS  Google Scholar 

  13. Crist WM, Garnsey L, Beltangady MS, et al (1990) Prognosis in children with rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Studies I and II. J Clin Oncol 8:443–452

    PubMed  CAS  Google Scholar 

  14. Raney RB, Anderson JR, Barr FG, et al. Rhabdomyosarcoma and undifferentiated sarcoma in first two decades of life: a selective review of Intergroup Rhabdomyosarcoma Study Group experience and rationale for Intergroup Rhabdomyosarcoma Study V. J. Pediatr Oncol 41:1–6, 2003

    Article  Google Scholar 

  15. Ferrari A, Casanova M (2005) Current chemotherapeutic strategies for rhabdomyosarcoma. Expert Rev Anticancer Ther 5:283–294

    Article  PubMed  CAS  Google Scholar 

  16. Stevens MC (2005) Treatment for childhood rhabdomyosarcoma: the cost of cure. Lancet Oncol 6:77–84

    Article  PubMed  Google Scholar 

  17. Stevens MC, Rey A, Bouvet N, et al (2005) Treatment of nonmetastatic rhabdomyosarcoma in childhood and adolescence: third study of the International Society of Paediatric Oncology — SIOP Malignant Mesenchymal Tumor 89. J Clin Oncol 23:2618–2628

    Article  PubMed  Google Scholar 

  18. Bisogno G, Ferrari A, Bergeron C, et al (2005) The ifosfamide, vincristine, actinomycin, doxorubicin (IVADo) regimen, an intensified chemotherapy for children with soft tissue sarcoma. A pilot study by the European pediatric Soft Tissue sarcoma Study Group. Cancer 103:1719–1724

    Article  PubMed  CAS  Google Scholar 

  19. Casanova M, Ferrari A, Bisogno G, et al (2004) Vinorelbine and low-dose cyclophosphamide in pediatric sarcomas: pilot study for the future European Rhabdomyosarcoma Protocol. Cancer 101:1664–1671

    Article  PubMed  CAS  Google Scholar 

  20. Casanova M, Ferrari A, Spreafico F, et al (2002) Vinorelbine in previously treated advanced childhood sarcomas: evidence of activity in rhabdomyosarcoma. Cancer 94:3263–3268

    Article  PubMed  CAS  Google Scholar 

  21. Wharam MD, Hanfelt JJ, Tefft MC, et al. (1997) Radiation therapy for rhabdomyosarcoma: local failure risk for Clinical Group III patients on Intergroup Rhabdomyosarcoma Study II. Int J Radiat Oncol Biol Phys 38:797–804

    Article  PubMed  CAS  Google Scholar 

  22. Schuck a, Mattke AC, Schmidt B, et al. (2004) Group II rhabdomyosarcoma nad rhabdomyosarcoma like tumors: is radiotherapy necessery? J Clin Oncol 22:143–149

    Article  PubMed  Google Scholar 

  23. Donaldson SS, Asmar l, Breneman J et al. (1995) Hyperfractionated radiation in children with rhabdomyosarcoma—results of an Intergroup Rhabdomyosarcoma Pilot Study. Int J Radiat Oncol Biol Phys 32:903–911

    Article  PubMed  CAS  Google Scholar 

  24. La Quaglia MP, Heller G, Ghavimi F, et al (1994) The effect of age at diagnosis on outcome in rhabdomyosarcoma. Cancer 73:109–117

    Article  PubMed  Google Scholar 

  25. Joshi D, Anderson JR, Paidas C. (2004) Age is an independent prognostic factor in rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Childre’s Oncology Group. Pediatr Blood Cancer 42:64–73

    Article  PubMed  CAS  Google Scholar 

  26. Ferrari A, Dileo P, Casanova M, et al (2003) Rhabdomyosarcoma in adults: a retrospective analysis of 171 patients treated at a single institution. Cancer 98:571–580

    Article  PubMed  Google Scholar 

  27. Spunt SL, Poquette CA, Hurt YS, et al (1999) Prognostic factors for children and adolescents with surgically resected nonrhabdomyosarcoma soft tissue sarcoma: an analysis of 121 patients treated at St Jude Children’s Research Hospital. J Clin Oncol 17:3697–3705

    PubMed  CAS  Google Scholar 

  28. Ferrari A, Casanova M, Collini P, et al (2005) Adulttype soft tissue sarcomas in pediatric age: experience at the Istituto Nazionale Tumori in Milan. J Clin Oncol 23:4021–4030

    Article  PubMed  Google Scholar 

  29. Pappo AS, Devidas M, Jenkins J, et al. (2005) Phase II trial of neoadjuvant vincristine, ifosfamide, and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcoma soft tissue sarcomas: a Pediatric Oncology Group Study. J Clin Oncol 23:4031–4038

    Article  PubMed  CAS  Google Scholar 

  30. Ferrari A, Casanova M (2005) New concepts for the treatment of pediatric non-rhabdomyosarcoma soft tissue sarcomas. Expert Rev Anticancer Ther 5:307–318

    Article  PubMed  CAS  Google Scholar 

  31. 1. Gronchi a, Casali PG, Mariani L, et al. (2005) Status of surgical margins and prognosis in adult soft tissue sarcomas of the extremities: a series of 911 consecutive patients treated at a single institution. J Clon Oncol 23:96–104

    Article  CAS  Google Scholar 

  32. Stojadinovic A, Leung DHY, Hoos A et al. (2002) Analysis of the prognostic significance of microscopic margins in 2084 localized primary adult soft tissue sarcomas. Ann Surg, 235:424–443

    Article  PubMed  Google Scholar 

  33. O’Sullivan 1. B, Davis AM, Turcotte R, et al. (2002) Preoperative versus postoperative radiotherapy in soft tissue sarcoma of the limbs: a randomized trial. Lancet 359:2235–2241

    Article  PubMed  Google Scholar 

  34. Khanfir K, Alzieu L, Terrier P, et al. (2003) Does adjuvant radiation therapy increases loco-regional control after optimal resection of soft-tissue sarcoma of the extremity? Eur J Cancer 39:1872–1880

    Article  PubMed  CAS  Google Scholar 

  35. Frustaci S, Gherlinzoni F, De Paoli A, et al (2001) Adjuvant chemotherapy for adult soft tissue sarcomas of extremities and girdles: results of the Italian randomized cooperative trial. J Clin Oncol 19:1238–1247

    PubMed  CAS  Google Scholar 

  36. Thierny JF, for the Sarcoma Meta-analysis Collaboration (1997) Adjuvant chemotherapy for localized resectable soft-tissue sarcoma of adults: meta-analysis of individual data. Lancet 350:1647–1654

    Article  Google Scholar 

  37. Ferrari A, Brecht IB, Koscielniak E, et al (2005) Could adjuvant chemotherapy have a role in surgicallyresected adult-type soft tissue sarcomas of children and adolescents? Pediatr Blood Cancer 45:128–134

    Article  PubMed  Google Scholar 

  38. Kattan MW, Leung DH, Brennan MF (2002) Postoperative nomogram for 12-year sarcoma-specific death. J Clin Oncol 20:791–796

    Article  PubMed  Google Scholar 

  39. Hayes-Jordan AA, Spunt SL, Poquette CA, et al. (2000) Nonrhabdomyosarcoma soft tissue sarcomas in children: is age at diagnoss an important variable? J Pediatr Surg. 35:948–954

    Article  PubMed  CAS  Google Scholar 

  40. Weitz J, Antonescu CR, Brennan MF (2003) Localized extremity soft tissue sarcoma: improved knowledge with unchanged survival over time. J Clin Oncol 21:2719–2725

    Article  PubMed  Google Scholar 

  41. Bergh P, Meis-Kindblom JM, Gherlinzoni F, et al (1999) Synovial sarcoma: identification of low and high risk groups. Cancer 85:2596–2607

    Article  PubMed  CAS  Google Scholar 

  42. Okcu MF, Munsell M, Treuner J, et al (2003) Synovial sarcoma of childhood and adolescence: a multicenter, multivariate analysis of outcome. J Clin Oncol 21:1602–1611

    Article  PubMed  Google Scholar 

  43. Ferrari A, Gronchi A, Casanova M, et al (2004) Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution. Cancer 101:627–634

    Article  PubMed  Google Scholar 

  44. Brecht IB, Ferrari A, Int-Veen C, et al (2006) Grossly-resected synovial sarcoma treated by the German and Italian Pediatric Soft Tissue Sarcoma Cooperative Groups: discussion on the role of adjuvant therapies. Pediatr Blood Cancer 46:11–17

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Dana Farber Cancer Institute, 44 Binney Street, Boston, MA, 02115, USA

    Karen H. Albritton M.D.

  2. Pediatric Oncology Unit, Istituto Nazionale Tumori, Via Venezian 1, 20133, Milano, Italy

    Andrea Ferrari M.D. & Michela Casanova M.D.

Authors
  1. Karen H. Albritton M.D.
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  2. Andrea Ferrari M.D.
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  3. Michela Casanova M.D.
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Editor information

Editors and Affiliations

  1. St. Charles Medical Center, Bend, Oregon, USA

    W. Archie Bleyer

  2. McMaster University, Hamilton, Ontario, Canada

    Ronald D. Barr

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© 2007 Springer-Verlag Berlin Heidelberg

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Albritton, K.H., Ferrari, A., Casanova, M. (2007). Soft-Tissue Sarcomas. In: Bleyer, W.A., Barr, R.D. (eds) Cancer in Adolescents and Young Adults. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68152-6_11

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  • DOI: https://doi.org/10.1007/978-3-540-68152-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40842-0

  • Online ISBN: 978-3-540-68152-6

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