Nomenclature
EC number
2.7.1.49
Systematic name
ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase
Recommended name
hydroxymethylpyrimidine kinase
Synonyms
EC 2.7.1.14 <4> (<4> hydroxymethylpyrimidine kinase [2]) [2]
EC 2.7.1.35 <4> (<4> pyridoxal kinase [2]) [2]
hydroxymethylpyrimidine kinase (phosphorylating)
pyridoxal kinase <4> [2]
CAS registry number
9026-55-5
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References
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Mizote, T.; Nakayama, H.: Purification and properties of hydroxymethylpyrimidine kinase from Escherichia coli. Biochim. Biophys. Acta, 991, 109–113 (1989)
Kim, Y.S.; Nosaka, K.; Downs, D.M.; Kwak, J.M.; Park, D.; Chung, I.K.; Nam, H.G.: A Brassica cDNA clone encoding a bifunctional hydroxymethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase involved in thiamin biosynthesis. Plant Mol. Biol., 37, 955–966 (1998)
Reddick, J.J.; Kinsland, C.; Nicewonger, R.; Christian, T.; Downs, D.M.; Winkler, M.E.; Begley, T.P.: Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase. Tetrahedron, 54, 15983–15991 (1998)
Mizote, T.; Tsuda, M.; Smith, D.D.; Nakayama, H.; Nakazawa, T.: Cloning and characterization of the thiD/J gene of Escherichia coli encoding a thiaminsynthesizing bifunctional enzyme, hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase. Microbiology, 145, 495–501 (1999)
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(2007). Hydroxymethylpyrimidine kinase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 • Transferases IX. Springer Handbook of Enzymes, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47815-7_12
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DOI: https://doi.org/10.1007/978-3-540-47815-7_12
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