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Abbreviations
- CGRP :
-
Calcitonin gene-related protein
- NGF :
-
Nerve growth factor
- NGF-R :
-
Nerve growth factor receptor
- p75 NTR :
-
p75 neurotrophin receptor
- RANTES :
-
regulated upon activation, normal T cell expressed and secreted
- SCID :
-
Severe combined immunodeficient
- SP :
-
Substance P
- TrkA :
-
Receptor tyrosine kinase A
- VIP :
-
Vasoactive intestinal peptide
References
Al’Abadie MSK, Senior HJ, Bleehen SS, et al (1992) Neurogenic changes in psoriasis. An immunohistochemical study. J Invest Dermatol 98:535
Aloe L, Levi-Mantalcini R (1977) Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Res 133:358–366
Aloe L, Alleva E, De Simone R (1990) Changes of NGF level in mouse hypothalamus following intermale aggressive behavior: biological and immunohistochemical evidence. Behav Brain Res 39:53–61
Aloe L, Probert L, Kollias G, et al (1993) The synovium of transgenic arthritic mice expressing human tumor necrosis factor contains a high level of nerve growthfactor. Growth Factors 9:149–155
Babu RJ, Kikwai L, Jaiani LT, et al (2004) Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II. Pharm Res 21:108–113
Bischoff SC, Dahinden CA (1992) Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils. Blood 79:2662–2669
Borson DB, Gruenert DC (1991) Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells. Am J Physiol 260:L83–L89
Bos JD, Hulsebosch HJ, Krieg SR, et al (1983) Immunocompetent cells in psoriasis: in situ immunophenotyping with monoclonal antibodies. Arch Dermatol Res 275:181–189
Bernstein JE, Parish LC, Rapaport M, et al (1986) Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris. J Am Acad Dermatol 15:504–507
Calvo CF, Chavanel G, Senik A (1992) Substance P enhances interleukin-2 expression in activated human T cells. J Immunol 148:3498–3504
Camisa C, O’Dorisio TM, Maceyko RF, et al (1990) Treatment of psoriasis with chronic subcutaneous administration of somatostatin analog 201–295 (sandostatin). An open lable pilot study. Clev Clin J Med 57:71–76
Chan J, Smoller BR, Raychaudhuri SP, et al (1997) Intraepidermal nerve fiber expression of calcitonin generelated peptide, vasoactive intestinal peptide and substance P in psoriasis. Arch Dermatol Res 289:611–616
Chang JC, Smith LR, Froning KJ, et al (1997) Persistance of T-cell clones in psoriatic lesions. Arch Dermatol 133:703–708
Erdos EG, Skidgel RA (1989) Neutral endopeptidase and related regulators of peptide hormones. FASEB J 3:145–151
Fantini F, Magnoni C, Brauci-Laudeis L, Pincelli C (1995) Nerve growth factor is increased in psoriatic skin. J Invest Dermatol 105:854–855
Farber EM, Peterson JB (1961) Variations in the natural history of psoriasis. Calif Med 95:6–11
Farber EM, Raychaudhuri SP (1997) Concept of total care: a third dimension in the treatment of psoriasis. Cutis 59:35–39
Farber EM, Nickoloff BJ, Recht B, et al (1986) Stress, symmetry, and psoriasis: possible role of neuropeptides. J Am Acad Dermatol 14:305–311
Farber EM, Cohen EN, Trozak DJ, et al (1991) Peptide T improves psoriasis when infused into lesions in nanogram amounts. J Am Acad Dermatol. 25:658–664
Farber EM, Rein G, Lanigan SW (1991) Stress and psoriasis — psychoneuroimmunologic mechanisms. Int J Dermatol 30:8–12
Fitzgerald M (1983) Capsaicin and sensory neurons: a review. Pain 15:109–130
Gottlieb AB, Lebwohl M, Shirin S, et al (2000) Anti-CD4 monoclonal antibody treatment of moderate to severe psoriasis vulgaris: results of a pilot, multicenter, multiple-dose, placebo-controlled study. J Am Acad Dermatol 43:595–604
Gozes Y, Brenneman DE, Fridkin M, et al (1991) A VIP antagonist distinguishes spinal cord receptors on spinal cord cells and lymphocytes. Brain Res 540:319–321
Haegerstrand A, Jonzon B, Dalsgaard CJ, et al (1989) Vasoactive intestinal polypeptide stimulates cell proliferation and adenylate cyclase activity of cultured human keratinocytes. Proc Natl Acad Sci USA 86:5993–5996
Hagerstrand A, Dalsgaard CJ, Jonzon B, et al (1990) Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA 87:3299–3303
Halliday DA, Zettler C, Rush RA, et al (1998) Elevated nerve growth factor levels in the synovial fluid of patients with inflammatory joint disease. Neurochem Res 23:919–922
Hughes HH, England R, Goldsmith DA (1981) Biofeedback and psychotherapeutic treatment of psoriasis: a brief report. Psycho Rep 48:99–102
Johansson O, Hilliges M, Talme T, et al (1994) Somatostatin immunoreactive cells in lesional psoriatic human skin during Peptide T treatment. Acta Derm Venereol (Stockh) 74:106–109
Kane D, Lockhart JC, Balint PV, et al (2005). Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint). Ann Rheum Dis 64:325–327
Krumins SA, Broomfield C (1992) Evidence of NK 1 and NK 2 tachykinin receptors and their involvement in histamine release in a murine mast cell line. Neuropeptides 21:65–72
Lambiase A, Bracci-Laudiero L, Bonini S, et al (1997) Human CD4 + T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors. J Allergy Clin Immunol 100:408–414
Leeman SE, Krause JE, Lembeck F (eds) (1991) Substance P and related peptides: cellular and molecular physiology. 18–21 July 1990, Worcester, Massachusetts, Proceedings; Ann NY Acad Sci 632:1–58, 263–271
Lei YH, Barnes PJ, Rogers DF (1992) Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96, 345, a new nonpeptide NK1 receptor antagonist. Br J Pharmacol 105:261–262
Lindsay RM, Harmar AJ (1989) Nerve growth factor regulates expression of neuropeptides genes in adult sensory neurons. Nature 337:362–364
Luppi P, Levi-Montalcini R, Bracci-Laudiero L, et al (1993) NGF is released into plasma during human pregnancy: an oxytocin-mediated response? Neuroreport 4:1063–1065
Manni L, Lundeberg T, Fiorito S, et al (2003) Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response. Clin Exp Rheumatol 21:6176–6124
Marcer D (1986) Biofeedback and Related Therapies in Clinical Practice. Aspen Publishers, Rockville, MD
Marcusson JA, Lazega D, Pert CB, et al (1989) Peptide T and psoriasis. Acta Derm Venereol Suppl (Stockh) 146:117–121
Matsuda H, Koyama H, Sato H, et al (1998) Role of nerve growth factor in cutaneous wound healing: accelerating effects in normal and healing-impaired diabetic mice. J Exp Med 187:297–306
Nadel JA (1991) Neutral endopeptide modulates neurogenic inflammation. Eur Respir J 4:745–754
Naukkarinen A, Nickoloff BJ, Farber EM (1989) Quantification of cutaneous sensory nerves and their substance P content in psoriasis. J Invest Dermatol 92:126–129
O’Connor TM, O’Connell J, O’Brien DI, et al (2004) The role of substance P in inflammatory diseases. J Cell Physiol 201:167–180
Pearce FL, Thompson HL (1986) Some characteristics of histamine secretion from rat peritoneal mast cells stimulated with nerve growth factor. J Physiol 372:379–393
Pincelli C, Haake AR, Benassi L, et al (1997) Autocrine nerve growth factor protects human keratinocytes from apoptosis through its high affinity receptor (TRK): a role for BCL-2. J Invest Dermatol 109:757–764
Rabier M, Wilkinson DI (1991) Neuropeptides modulate Leukotrine B4 Mitogenicity toward cultured keratinocytes. Clin Res 39:536a
Radhakrishna V, Henry JL (1991) Novel substance P antagonist, CP-96, 345, blocks responses of cat spinal dorsal horn neurons to noxious cutaneous stimulation and substance P. Neurosci Lett 132:39–43
Raychaudhuri SP, Farber EM (1993) Are sensory nerves essential for the development of psoriasis lesions? J Am Acad Dermatol 28:488–489
Raychaudhuri SP, Gross J (2000) A comparative study of pediatrie onset psoriasis with adult onset psoriasis. Pediatr Dermatol 17:174–178
Raychaudhuri SP, Gross J (2000) Psoriasis risk factors: role of lifestyle practices. Cutis 66:348–352
Raychaudhuri SP, Jiang W-Y, Farber EM (1998) Psoriatic keratinocytes express high levels of nerve growth factor. Acta Derm Venereol 78:84–86
Raychaudhuri SP, Farber EM, Raychaudhuri SK (1999) Immunomodulatory effects of peptide T on Th 1/Th 2 cytokines. Int J Immunopharmacol 21:609–615
Raychaudhuri SP, Jiang WY, Farber EM, et al (1999) Upregulation of RANTES in psoriatic keratinocytes: a possible pathogenic mechanism for psoriasis. Acta Derm Venereol 79:9–11
Raychaudhuri SP, Farber EM, Raychaudhuri SK (2000) Role of nerve growth factor in RANTES expression by keratinocytes. Acta Derm Venereol 80:247–250
Raychaudhuri SP, Dutt S, Raychaudhuri SK, et al (2001) Severe combined immunodeficiency mouse-human skin chimeras: a unique animal model for the study of psoriasis and cutaneous inflammation. Br J Dermatol 144:931–939
Raychaudhuri SP, Sanyal M, Weltman H, et al (2004) K252a, a high-affinity nerve growth factor receptor blocker, improves psoriasis: an in vivo study using the severe combined immunodeficient mouse-human skin model. J Invest Dermatol 122:812–819
Raychaudhuri SP, Jiang WY, Raychaudhuri SK (2008) Revisiting the Koebner phenomenon: role of NGF and its receptor system in the pathogenesis of psoriasis. Am J Pathol 172:961–971
Ruff MR (1989) Peptide T. Drugs Future 14:1049–1051
Schall TJ (1991) Biology of the RANTES/SIS cytokine family. Cytokine 3:165–183
Scholzen TE, Steinhoff M, Bonaccorsi P, et al (2001) Neutral endopeptidase terminates substance P-induced inflammation in allergie contact dermatitis. J Immunol 166:1285–1291
Schwartz J, Pearson J, Johnson E (1982) Effect of exposure to anti-NGF on sensory neurons of adult rats and guinea pigs. Brain Res 244:378–381
Smith HC, Barker JN, Morris RW, et al (1993) Neuropeptides induce rapid expression of endothelial cell adhesion molecules and elicit granulocytic infiltration in human skin. J Immunol 151:3274–3282
Snider RM, Constantine JW, Lowe JA, et al (1991) A potent nonpeptide antagonist of the substance P (NK1) receptor. Science 251:435–437
Talme T, Lund-Rosell B, Sundquist KG, et al (1994) Peptide T: a new treatment for psoriasis? Acta Derm Venereol (Stockh) 186:76–78
Thorpe LW, Werrbach-Perez K, Perez-Polo JR (1987) Effects of nerve growth factor on the expression of IL-2 receptors on cultured human lymphocytes. Ann NY Acad Sci 496:310–311
Valdimarsson H, Baker BS, Jonsdottir I, et al (1986) Psoriasis: a disease of abnormal keratinocyte proliferation induced by T lymphocytes. Immunol Today 7:256–259
Vaupel R, Jarry H, Schlomer HT, et al (1988) Differential response of substance P containing subtypes of adrenomedullary cells to different Stressors. Endocrinology 123: 2140–2145
Wallengren J (1991) Substance P antagonist inhibits immediate and delayed type cutaneous hypersensitivity reactions. Br J Dermatol 124:324–328
Wallengren J, Moller H (1988) Some neuropeptides as modulators of experimental contact allergy. Contact Dermatitis 19:351–354
Wallengren J, Ekman R, Sunder F (1987) Occurrence and distribution of neuropeptides in human skin. An immunocytochemical and immunohistochemical study on normal skin and blister fluid from inflamed skin. Acta Derm Venereol (Stockh) 67:185–192
Waxman D (1973) Behavior therapy of psoriasis — a hypnoanalytic and counter conditioning technique. Postgrad Med J 49:591–595
Wetterberg L, Alexius B, Saaf J, et al (1987) Peptide T in treatment of AIDS (letter). Lancet 1:159
Wiesenfeld-Hallin Z, Xu Xj, Hakanson R, et al (1990) The specific antagonistic effect of intrathecal spantide II on substance P stimulation-induced facilitation of the nociceptive flexor reflex in rat. Brain Res 526:284–290
Wilkinson DI (1989) Mitogenic effect of substance P and CGRP on Keratinocytes. J Cell Biol 107:509a
Wilkinson DI, Theeuwes MI, Farber EM (1994) Nerve growth factor increases the mitogenicity of certain growth factors for cultured human keratinocytes: A comparison with epidermal growth factor. Exp Dermatol 3:239–245
Wrone-Smith T, Nickoloff BJ (1996) Dermal injection of immunocytes induces psoriasis. J Clin Invest 98:1878–1887
Wyatt S, Shooeter EM, Davies AM (1990) Expression of the NGF receptor gene in sensory neurons and their cutaneous targets prior to and during innervation. Neuron 2:421–427
Xu Xj, Hao JX, Wiesenfeld-Hallin Z, et al (1991) Spantide II, a novel tachykinin antagonist inhibits plasma extravasation induced by antidromic C-fiber stimulation in rat hind paw. Neuroscience 42:731–737
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Raychaudhuri, S.P., Raychaudhuri, S.K. (2009). Neuroimmunologic Cascades in the Pathogenesis of Psoriasis and Psoriatic Arthritis. In: Granstein, R.D., Luger, T.A. (eds) Neuroimmunology of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35989-0_17
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