Zusammenfassung
Obwohl Infektionen mehr denn je zu den wesentlichen Komplikationen orthopädischer und traumatologischer Implantate zählen, gibt es für die klinische Anwendung noch keine etablierten antibakteriellen Implantate. Antiinfektiöse Oberflächenbeschichtungen könnten die bakterielle Besiedelung der Implantate hemmen und dadurch die Infektionsraten reduzieren. Aktuelle Entwicklungen werden im folgenden Beitrag vorgestellt und diskutiert. Wesentlich ist in diesem Zusammenhang die Beachtung der Biokompatibilität, um eine sichere ossäre Integration der beschichteten Implantate nicht zu gefährden. Aufgrund der zunehmenden Häufigkeit antibiotikaresistenter Bakterien besteht zudem die Notwendigkeit der Entwicklung antibakterieller Oberflächen mit Breitspektrumwirkung, insbesondere gegen antibiotikaresistente Infektionserreger.
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Gollwitzer, H., Gerdesmeyer, L. (2006). Antiinfektiöse Oberflächenbeschichtung. In: Ossäre Integration. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-35687-5_8
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DOI: https://doi.org/10.1007/978-3-540-35687-5_8
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