Abstract
The development of materials and strategies that can promote faster bone healing and improved regeneration of bony defects is of high interest. Graphene and its derivatives (graphene oxide and reduced graphene oxide) have remarkable mechanical properties, can be chemically modified and allow the attachment of molecules and proteins. Due to these characteristics, these carbon-based materials have received increasing attention for several biomedical applications. As graphenes can improve mechanical properties of several biomaterials, induce, and increase cell differentiation toward osteoblasts, they have emerged as interesting alternatives for to promote bone regeneration. Herein, the key achievements made with graphenes for bone tissue engineering are presented with particular emphasis on their combination with biomaterials for bone regeneration and as coatings for biomedical implants.
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Acknowledgments
The authors were supported by National University Health System (NUHSRO/2014/017/B2B/02), National University of Singapore (R-221-000-091-112) and National Research Foundation CRP award “Novel 2D materials with tailored properties: beyond graphene” (R-144-000-295-281).
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Dubey, N., Decroix, F.E.D., Rosa, V. (2016). Graphene: An Emerging Carbon Nanomaterial for Bone Tissue Engineering. In: Gonçalves , G., Marques, P., Vila, M. (eds) Graphene-based Materials in Health and Environment. Carbon Nanostructures. Springer, Cham. https://doi.org/10.1007/978-3-319-45639-3_5
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