Abstract
Synthetic biology is mainly focused on the design and construction of new biological parts. Assembly of these parts aids with the creation of synthetic biological pathways. This ultimately leads to an overlap of disciplines in which the synthetic parts are applied to a microbial production host and metabolic engineering for production of value-added compounds. This chapter intends to highlight the supportive input of synthetic biology parts, devices and modules to metabolic pathway engineering for the production of chemicals and fuels. Synthetic bricks find applications on the genome, transcriptome and proteome levels. By exemplifying several applications on the different levels, this chapter intends to give a brief overview of recent developments in the field; furthermore, upcoming developments in protein scaffolding and spatial organisation of pathways in bacterial microcompartments are discussed.
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Marx, H., Pflügl, S., Mattanovich, D., Sauer, M. (2016). Synthetic Biology Assisting Metabolic Pathway Engineering. In: Glieder, A., Kubicek, C., Mattanovich, D., Wiltschi, B., Sauer, M. (eds) Synthetic Biology. Springer, Cham. https://doi.org/10.1007/978-3-319-22708-5_7
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DOI: https://doi.org/10.1007/978-3-319-22708-5_7
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