Chapter

Endometriosis

Part of the series SpringerBriefs in Reproductive Biology pp 17-21

Theories on Endometriosis

  • Sajal GuptaAffiliated withAssistant Professor, Lerner College of Medicine and Case Western Reserve University, American Center for Reproductive Medicine, Cleveland Clinic Email author 
  • , Avi HarlevAffiliated withAmerican Center for Reproductive MedicineLecturer, Soroka University Medical Center, Fertility and IVF Unit, Ben-Gurion University of the Negev
  • , Ashok AgarwalAffiliated withProfessor, Lerner College of Medicine and Case Western Reserve University, American Center for Reproductive Medicine, Cleveland Clinic
  • , Elizabeth PandithuraiAffiliated withAmerican Center for Reproductive Medicine, Cleveland Clinic

* Final gross prices may vary according to local VAT.

Get Access

Abstract

There are several theories as to how endometriosis develops, but the most widely accepted one is Sampson’s theory. First hypothesized in 1927, Sampson’s theory [1] states that three elements are required to cause endometriosis: retrograde menstruation, the presence of viable cells within the retrograde menstruation, and the implantation of these viable endometrial cells, which continue to grow and form peritoneal lesions [1].