Abstract
In this pilot study we investigated whether a transcortical pathway mediates the short-latency responses elicited in the contralateral gastrocnemius lateralis (cGL) by ipsilateral posterior tibial nerve (iPTN) stimulation. For this purpose, single pulse sub-threshold (90% active motor threshold) transcranial magnetic stimulation (subTMS) was applied in combination with iPTN stimulation at several interstimulus intervals (ISI) while the subjects (n=6) walked. SubTMS has been shown to reduce cortical output to the target muscle, inducing a suppression in the EMG signal of the voluntary activated muscle. While no differences were observed for the first component to the response, a considerable depression of the second part, referred to as long-latency component (LLC) was observed when the subTMS was timed such that the induced suppression would coincide with this component. These results strongly suggest the cortical control of the LLC in the cGL response. This allows for an enhanced flexibility during unexpected perturbations, ensuring that the appropriate output is produced in accord with the functional demand.
Keywords
- Transcranial Magnetic Stimulation
- Motor Evoke Potential
- Experimental Brain Research
- Target Muscle
- Stride Time
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Mrachacz-Kersting, N., Gervasio, S., Farina, D., Sinkjær, T. (2014). Cortical Contribution to Crossed Reflexes in Walking Humans. In: Jensen, W., Andersen, O., Akay, M. (eds) Replace, Repair, Restore, Relieve – Bridging Clinical and Engineering Solutions in Neurorehabilitation. Biosystems & Biorobotics, vol 7. Springer, Cham. https://doi.org/10.1007/978-3-319-08072-7_84
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DOI: https://doi.org/10.1007/978-3-319-08072-7_84
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-08071-0
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