Abstract
Traditional Chinese Medicine (TCM) is an invaluable human heritage for its documented clinical experience of thousands of years. However, it remains problematic for how to make the best use of this treasure. A major concern of TCM modernization is the credibility of the information. A large number of these clinical records are scattered in various notes, books and research reports and there is absence of good tool to scientifically evaluate this tremendous amount of information. Our recent preliminary study has shown that the quality of TCM information is generally poor and unreliable. To provide a platform that provides TCM information with verified quality as a base for TCM-originated product development, we established a proprietary SAPHRON TCM data system to quantitatively evaluate the quality of TCM information, which ranks TCM prescriptions, herbs, active ingredients as well as potential lead compounds based on the reliability of available information for recommendation. Our results have showed that, scientific approaches with modern technology of informatics and statistics can be applied to TCM information in a high throughput fashion.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
S. Chen, Y. Tang, X. Liang, The simple discussion of evil compatibility in traditional Chinese medicine. J. Liaoning Univ. TCM 14(2), 105–106 (2012)
Chinese pharmacopoeia, 1, 212–213 (2010)
Chunping Yin, Jizhou Wu, Advances in studies on immunoregulation of Alism aorientalis and its active constituents. Chin. Trad. Herb. Drugs 32(12), 1132–1133 (2001)
H. Cunningham, Information extraction, automatic, in Encyclopedia of Language & Linguistics, vol. 5, 2nd edn. Oxford: Elsevier, pp. 665–677 (2006)
Erxin Shang, Xinsheng Fan, Jinao Duan, Liang Ye, Data mining study on incompatibility characters of Chinese herbal medicine in accordance with association rules. J. Nanjing TCM Univ. 26(6), 421–424 (2010)
Z. Gu, Research on prescription classification using text classification technology. J. Liaoning Univ. TCM 12(2), 45–46 (2010)
X. Hu, Z. Cheng, S. Wang, N. Fang, S. Yu, Effects of Rhizoma Alismatis decoction on levels of blood lipids in rat. Lishizhen Med. Meteria Medica Res. 22(9), 2073–2074 (2011)
D. Li, Study on the bacterial endotoxins test of Shenmai injection. Strait Pharm. J. 20(3), 59–61 (2008)
Lixing Nie, Yan Liu, Gangli Wang, Hongyu Jin, Ruichao Lin, Direct determination of 26 elements in traditional Chinese medicine injection. Chin. Pharm. J. 46(11), 866–868 (2011)
H. Lu, R. Chen, M. Wu, Evaluation of high-dose Senmai in treating patients with advanced cancer. Chin. Trad. Pat. Med. 26(9), 729–731 (2004)
Minhua He, Jianxin Wu, Ping Zhou, Rongxiang Niu, Kunlun Tian, The protection effect of shenmai injection on rabbits with renal ischernic/reperfusion injurn. J. Chin. Clin. Med. 5(6), 5–6 (2004)
X. Shi, J. Yang, C. Zhao, J. Xiong, G. Xu, Application of fingerprint chromatogram in quality control of Shen-Mai injection. Chin. J. Chromatogr. 20(4), 299–303 (2002)
Shugang Yuan, Yingjie Zhang, Shaodan Ma, Guihua Su, Shibao Ruan, The optimal dose ratio experimental study of Zexie Tiaozhi granule on adjust lipids of hyperlipidemic rats. Clin. J. Chin. Med. 3(16), 5–6 (2011)
Shuzi Li, Zaijiu Jin, Shanyu Zhang, The effects of alisma orientalis’s extracts on blood lipid and antioxidation of experimental hyperlipidemia mice. China Pract. Med. 3(32), 7–9 (2008)
L. Wang, Q. Wu, Q. Zhang, G. Peng, A. Ding, Basic study of diuretic active compounds in Rhizoma Alismatis. West China J. Pharm. Sci. 23(6), 670–672 (2008)
Wei Hu, Junying Ding, Shixiang Jia, Zhongsi Lin, ShenMai injection combined with chemotherapy in the treatment of advanced lung cancer. J. Liaoning Univ. TCM 10(11), 108–109 (2008)
Weirong Zhu, Lan Zheng, Yuanbiao Guo, Jianming Yuan, Xiaoheng Shen, Clinical research of intraperitoneal chemotherapy plus Shenmai injection in treating advanced colorectal cancer. J. Chin. Integr. Med. 3(4), 266–269 (2005)
Weixin Guo, Qidong Yang, Xiaoyun Xie, Wang Miao, Effects of Shenmai injection on number and activity of endothelial progenitor cells from human peripheral blood. Stroke Nerv. Dis. 15(1), 37–40 (2008)
F. Xiaohui, W. Yi, C. Yiyu, LC/MS fingerprinting of Shenmai injection: A novel approach to quality control of herbal medicines. J. Pharm. Biomed. Anal. 40, 591–597 (2006)
Yan Liu, Xin Fan, Kang Li, Application of association rules on selecting the prescription from classics of traditional Chinese medicine. Chin. J. Hosp. Stat. 17(4), 294–297 (2010)
Yang Cao, Peng Li, Kaiji Tan, Ruishen Chen, Clinical observation on Shenmai injection in preventing and treating adverse reaction of chemotherapy on advanced non-small cell lung cancer. Chin. J. Integr. Trad. West. Med. 26(6), 550–552 (2006)
Ye Liang, Xinsheng Fan, Chongjun Wang, Erxin Shang, Fengying Zhao, Huan Zhang, Discussion data mining technology applying on prescription. Med. Inf. 21(10), 1734–1737 (2008)
Zhanpeng Tan, Yi Luo, Jiqiang Li, The data mining analysis of the Chinese medicine principle and ZHENG-oriented effects of 43 medical records on dysentery by the contemporary famous veteran Chinese medical doctors. Clin. Med. Eng. 18(3), 412–414 (2011)
Zhiqiang Ouyang, Lisheng Jiang, Ruyi Wang, Seqi Lin, Qiming Zhang, Qinglin Zha, Aiping Lv, The regularity of the compatibility and corresponding prescriptions with syndrome of treating toothache with TCM in 63 case of famous practitioner of Chinese medicine about toothache on publication. J. Jiangxi Univ. TCM 19(5), 88–90 (2007)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Yang, J. et al. (2014). TCM Data Mining and Quality Evaluation with SAPHRONTM System. In: Poon, J., K. Poon, S. (eds) Data Analytics for Traditional Chinese Medicine Research. Springer, Cham. https://doi.org/10.1007/978-3-319-03801-8_12
Download citation
DOI: https://doi.org/10.1007/978-3-319-03801-8_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-03800-1
Online ISBN: 978-3-319-03801-8
eBook Packages: Computer ScienceComputer Science (R0)