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Tight contact technique during side-to-side laser tissue soldering of rabbit aortas improves tensile strength

  • Conference paper
Changing Aspects in Stroke Surgery: Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass

Part of the book series: Acta Neurochirurgica Supplements ((NEUROCHIRURGICA,volume 103))

Abstract

Background

Cerebral revascularization may be indicated either for blood flow preservation or flow augmentation, often in clinical situations where neither endovascular nor standard surgical intervention can be performed. Cerebral revascularization can be performed by using a temporary occlusive or a non-occlusive technique. Both of these possibilities have their specific range of feasibility. Therefore non-occlusive revascularization techniques have been developed. To further reduce the risks for patients, less time consuming, sutureless techniques such as laser tissue soldering are currently being investigated.

Method

In the present study, a new technique for side-to-side anastomosis was developed. Using a’ sandwich technique’, two vessels are kept in close contact during the laser soldering. Thoraco-abdominal aortas from 24 different rabbits were analyzed for laser irradiation induced tensile strength. Two different irradiation modes (continuous and pulsed) were used. The results were compared to conventional, noncontact laser soldering. Histology was performed using HE, Mason’s Trichrome staining.

Findings

The achieved tensile strengths were significantly higher using the close contact’ sandwich technique’ as compared to the conventional adaptation technique. Furthermore, tensile strength was higher in the continuously irradiated specimen as compared to the specimen undergoing pulsed laser irradiation. The histology showed similar denaturation areas in both groups. The addition of a collagen membrane between vessel components reduced the tensile strength.

Conclusion

These first results proved the importance of close and tight contact during the laser soldering procedure thus enabling the development of a’ sandwich laser irradiation device’ for in vivo application in the rabbit.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Inselspital Bern, University of Bern, Bern, 3010, Switzerland

    A. Alfieri, A. Bregy & Michael Reinert M.D.

  2. Department of Plastic Surgery, Inselspital Bern, University of Bern, Bern, Switzerland

    M. Constantinescu & A. Banic

  3. Institute of Applied Physics, University of Bern, Bern, Switzerland

    F. Stuker & M. Frenz

  4. Institute for Pathology, University of Bern, Bern, Switzerland

    T. Schaffner

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Editor information

Editors and Affiliations

  1. Neurochirurgie FMH, Zurich, Switzerland

    Yasuhiro Yonekawa

  2. Department of Neurosurgery, Kyoto National Hospital, Kyoto, Japan

    Tetsuya Tsukahara

  3. Institut für Neuroradiologie, Universitätsspital Zurich, Zurich, Switzerland

    Anton Valavanis

  4. Neurochirurgische Klinik, Universitätsspital Zurich, Zurich, Switzerland

    Nadia Khan

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Alfieri, A. et al. (2008). Tight contact technique during side-to-side laser tissue soldering of rabbit aortas improves tensile strength. In: Yonekawa, Y., Tsukahara, T., Valavanis, A., Khan, N. (eds) Changing Aspects in Stroke Surgery: Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass. Acta Neurochirurgica Supplements, vol 103. Springer, Vienna. https://doi.org/10.1007/978-3-211-76589-0_16

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  • DOI: https://doi.org/10.1007/978-3-211-76589-0_16

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-76588-3

  • Online ISBN: 978-3-211-76589-0

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