Abstract
The term hepatobiliary disease refers to acute or chronic disorders of the hepatic cells and/or the biliary tract. In this chapter are firstly described the clinical forms of the hepatobiliary disease and, secondly, the pathophysiologic mechanisms that are responsible for hepatic cell damage. Since surgery in patients with pre-existing severe hepatobilary disease is associated with significant morbidity and mortality rates, the anaesthesiologist should be able to diagnose and evaluate hepatic dysfunction during the perioperative period. Even with careful attention to history and symptoms, some cases of liver disease can be misdiagnosed. However, in most cases the cause of misdiagnosis results from failure to ask simple questions or to look for obvious findings on physical examination. Laboratory investigation of the hepatobiliary disease lacks in specificity in defining a certain liver disease. Instead of this, laboratory testing of liver function helps to differentiate the diagnosis among hepatocellular injury, impaired hepatocellular synthetic function and cholestasis
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Georgakis, P., Rizzotti, L., Katsouli-Liapis, I. (2006). Hepatobiliary Disease and Anaesthesia. In: Karaliotas, C.C., Broelsch, C.E., Habib, N.A. (eds) Liver and Biliary Tract Surgery. Springer, Vienna. https://doi.org/10.1007/978-3-211-49277-2_9
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DOI: https://doi.org/10.1007/978-3-211-49277-2_9
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