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Animal Models of Obesity

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Physiology and Physiopathology of Adipose Tissue

Abstract

This chapter reviews rodent models of obesity and how they provide crucial insight into our understanding of physiological, environmental, genetic, and epigenetic bases of human obesity. Naturally occurring or genetically modified animal models represent precious and necessary tools to explore the complexity of energy balance regulation and to test innovative therapeutic intervention in obesity, of which leptin treatment for leptin-deficient patients is a striking example.

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Authors and Affiliations

  1. Institut des maladies cardiométaboliques et de la nutrition (IHU ICAN), Paris, France

    Michèle Guerre-Millo

  2. Nutriomique U872 équipe 7, Centre de recherche des Cordeliers, INSERM, UPMC, 15, rue de l’école de médecine, 75006, Paris, France

    Michèle Guerre-Millo

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  1. Michèle Guerre-Millo
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Correspondence to Michèle Guerre-Millo .

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Editors and Affiliations

  1. Rue de la Chine 4, Paris, 75020, France

    Jean-Philippe Bastard

  2. Hôpital Saint-Antoine, Paris, France

    Bruno Fève

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Guerre-Millo, M. (2013). Animal Models of Obesity. In: Bastard, JP., Fève, B. (eds) Physiology and Physiopathology of Adipose Tissue. Springer, Paris. https://doi.org/10.1007/978-2-8178-0343-2_18

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  • DOI: https://doi.org/10.1007/978-2-8178-0343-2_18

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  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0342-5

  • Online ISBN: 978-2-8178-0343-2

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