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Systèmes d’information pour l’amélioration de la qualité en santé pp 37–46Cite as

Représentation formelle des critères d’éligibilité aux essais cliniques: Exigences sémantiques de représentation des relations

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Part of the book series: Informatique et Santé ((INFORMATIQUE,volume 1))

Abstract

Reference terminologies based and computable knowledge representations for eligibility criteria are needed to provide computer-based decision support for automated screening, and other purposes. RuleEd and ERGO, a tool and an ad-hoc language for encoding CT, are recent initiatives to achieve this goal. RuleEd defines a collection of connectors that aims at connecting domain concepts to represent criteria in a formal way. Our study is focused on these connectors. Method: We assessed the RuleEd native collection (Ci) of connectors and we proposed an improved new version (Co). Then, from two samples of Ci and Co, we evaluated how SNOMED CT and NCIT could encode and represent the RuleEd connectors. Results: RuleEd provides 362 connectors organized in 10 categories. These categories are confusing. Many Ci connectors are redundant and we reduced Ci into 133 Co connectors (−64%). SNOMED CT has the best coverage rate for encoding Ci and Co connectors (47% up to 61%). Nevertheless, both terminologies have still open issues, especially a lack of formal representation and need to be improved, to be used for an automatic reasoning purpose.

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Author information

Authors and Affiliations

  1. Unité Inserm U936, Université de Rennes 1, France

    Murielle Massot, Marc Cuggia, Régis Duvauferrier & Valérie Bertaud-Gounot

  2. Centre de soins dentaires, CHU de Rennes, France

    Murielle Massot & Valérie Bertaud-Gounot

Authors
  1. Murielle Massot
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  2. Marc Cuggia
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  3. Régis Duvauferrier
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  4. Valérie Bertaud-Gounot
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Corresponding author

Correspondence to Valérie Bertaud-Gounot .

Editor information

Editors and Affiliations

  1. Département d’Information et d’Informatique Médicale, Centre Hospitalier Universitaire de Nice Hôpital de Cimiez, 4 Avenue Reine Victoria, B.P. 1179, 06003, Nice Cedex 1, France

    Pascal M. Staccini

  2. Service de Médecine Interne, C.H.U. Mongi Slim - La Marsa, 2046, Sidi-Daoud, Tunis, Tunisie

    Ali Harmel

  3. Equipe CISMeF, Cour Leschevin Porte 21, 3ème étage 1 rue de Germont, 76031, Rouen Cedex, France

    Stéfan J. Darmoni

  4. Service de Neurologie, C.H.U. Razi, 2010, La Manouba, Tunis, Tunisie

    Riadh Gouider

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© 2011 Springer-Verlag France

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Massot, M., Cuggia, M., Duvauferrier, R., Bertaud-Gounot, V. (2011). Représentation formelle des critères d’éligibilité aux essais cliniques: Exigences sémantiques de représentation des relations. In: Staccini, P.M., Harmel, A., Darmoni, S.J., Gouider, R. (eds) Systèmes d’information pour l’amélioration de la qualité en santé. Informatique et Santé, vol 1. Springer, Paris. https://doi.org/10.1007/978-2-8178-0285-5_4

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  • DOI: https://doi.org/10.1007/978-2-8178-0285-5_4

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0284-8

  • Online ISBN: 978-2-8178-0285-5

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