Résumé
Ce chapitre est principalement consacré à la prise en charge diagnostique et thérapeutique des hyperandrogénies. Seront également abordées les manifestations dermatologiques associées à la ménopause, la prise d’œstroprogestatifs ainsi que les affections dermatologiques ayant un lien direct avec les stéroïdes sexuels.
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Références
Pelletier G, Ren L. Localization of sex steroid receptors in human skin. Histol Histopathol 2004; 19:629–636.
Kovacs WJ. The androgen receptor. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 53–61, ch. 6.
Sawaya ME, Shalita AR. Androgen receptor polymorphisms (CAG repeat lengths) in androgenetic alopecia hirsutism and acne. J Cutan Med Surg 1998; 3:9–15.
Calvo RM, Asuncion M, Sancho J et al. The role of the CAG repeat polymorphism in the androgen receptor gene and of skewed X-chromosome inactivation in the pathogenesis of hirsutism. J Clin Endocrinol Metab 2000; 85: 1735–1740.
Mowszowicz I, Melanitou E, Doukani A et al. Androgen binding capacity and 5 alphareductase activity in pubic skin fibroblasts from hirsute patients. J Clin Endocrinol Metab 1983; 56:1209–1213.
Hatch R, Rosenfield RL, Kim MH, Tredway D. Hirsutism: Implications, etiology, and management. Am J Obstet Gynecol 1981; 140:815–830.
Ayoub N, Rouphael N, Tomb R. [Hirsutism]. Ann Dermatol Venereol 2002; 129:1140–1150.
Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961; 21:1440–1447.
Redmond GP. Clinical evaluation of the woman with an androgenic disorder. In Androgenic disorders. Redmond GD, ed, Raven Press, New York, 1995, p. 1–20.
Strickler JH, Garrett AB. Androgen excess and hair loss in women. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 141–147, ch. 14.
Cavelier-Balloy B, Assouly P. [Role and limitations of skin biopsy in the diagnosis of alopecia]. Ann Dermatol Venereol 2009; 136:182–198.
AFSSAPS Traitement de l’acné par voie générale: argumentaire. Ann Dermatol Venereol 1999; 126:224–231.
Dreno B, Alirezai M, Auffret N et al. Corrélation clinique et psychologique dans l’acné: utilisation des grilles ECLA et CADI. Ann Dermatol Venereol 2007; 134:451–455.
Dreno B, Finlay AY, Nocera T et al. The Cardiff Acne Disability Index: cultural and linguistic validation in French. Dermatology 2004; 208:104–108.
Azziz R, Sanchez LA, Knochenhauer ES et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab 2004; 89:453–462.
Cortet-Rudelli C, Desailloud R, Dewailly D. Drug-induced androgen excess. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 613–621, ch. 59.
Schiebinger RJ, Chrousos GP, Cutler GB Jr et al. The effect of serum prolactin on plasma adrenal androgens and the production and metabolic clearance of dehydroepiandrosterone sulfate in normal and hyperprolactinemic subjects. J Clin Endocrinol Metab 1986; 62:202–209.
Hagag P, Hertzianu I, Ben-Shlomo A et al. Androgen suppression and clinical improvement with dopamine agonists in hyperandrogenic hyperprolactinemic women. J Reprod Med 2001; 46:678–684.
Regnier C, Bennet A, Malet D et al. Intraoperative testosterone assay for virilizing ovarian tumor topographic assessment: report of a Leydig cell tumor of the ovary in a premenopausal women with an adrenal incidentaloma. J Clin Endocrinol Metab 2002; 87:3074–3077.
Pugeat M, Mirakian P, Dutrieux-Berger N, Forest MG, Tourniaire J. Androgen secreting ovarian neoplasms. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 555–568, ch. 54.
Tita P, Spina A, Briguglia G et al. Clinical features and hormonal characteristics in a case of ovarian arrhenoblastoma. J Endocrinol Invest 1996; 19:484–487.
Derksen J. Androgen secreting adrenal neoplasms. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 545–553, ch. 53.
Azziz R, Dewailly D Diagnosis, screening and treatment of nonclassic 21-hydroxylase deficiency. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 181–192, ch. 18.
Degitz K, Placzek M, Arnold B et al. Congenital adrenal hyperplasia and acne in male patients. Br J Dermatol 2003; 148:1263–1266.
White PC, Johrer K, Kofler R. Steroid 11 beta-hydroxylase deficiency. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 193–200, ch. 19.
Pang S. Inherited 3 beta-hydroxysteroid dehydrogenase deficiency disorder. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 201–213, ch. 20.
Charmandari E, Kino T, Souvatzoglou E et al. Natural glucocorticoid receptor mutants causing generalized glucocorticoid resistance: molecular genotype, genetic transmission, and clinical phenotype. J Clin Endocrinol Metab 2004; 89:1939–1949.
Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81:19–25.
Ortega-Gonzalez C, Luna S, Hernandez L et al. Responses of serum androgen and insulin resistance to metformin and pioglitazone in obese insulin-resistant women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005; 90:1360–1365.
Lord JM, Flight IH, Norman RJ. Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ 2003; 327: 951–953.
Ibanez L, Potau N, Marcos MV, De Zegher F. Adrenal hyperandrogenism in adolescent girls with a history of low birthweight and precocious pubarche. Clin Endocrinol (Oxf) 2000; 53: 523–527.
Nestler JE, Whitfield JB, Williams TY et al. Genetics of serum dehydroepiandrosterone sulfate and its relationship to insulin in a population-based cohort of twin subjects. J Clin Endocrinol Metab 2002; 87:682–686.
Nagamani M. Polycystic ovarian syndrome variants: hyperthecosis. In Reproductive endocrinology, surgery and technology. Adashi EY, Rock JA, Rosenwaks Z, eds, Lippincott-Raven, Philadelphia, 1996, p. 1257–1269, ch. 63.
Hughesdon PE. Morphology and morphogenesis of the Stein Leventhal ovary and of so-called «hyperthecosis». Obstet Gynecol Surv 1982; 37:59–77.
Azziz R, Carmina E. Idiopathic hirsutism: definition, prevalence and inheritance. In Androgen excess disorders in women. Azziz R, Nestler JE, Dewailly D, eds, Lippincott-Raven, Philadelphia, 1997, p. 529–534, ch. 51.
Futterweit W, Dunaif A, Yeh H, Kingsley P. The prevalence of hyperandrogenism in 109 consecutive females with diffuse alopecia. J Am Acad Dermatol 1988; 5:831–836.
Slayden SM, Moran C, Sams WM Jr et al. Hyperandrogenemia in patients presenting with acne. Fertil Steril 2001; 75:889–892.
Arnaldi G, Angeli A, Atkinson AB et al. Diagnosis and complications of Cushing’s syndrome: a consensus statement. J Clin Endocrinol Metab 2003; 88:5593–5601.
Chanson P, Bertherat J, Beckers A et al. Consensus français sur la prise en charge de l’acromégalie. Ann Endocrinol 2009; 70:92–106.
Rayfield EJ, Rose LI, Cain JP et al. ACTH-responsive, dexamethasone-suppressible adrenocortical carcinoma. N Engl J Med 1971; 284:591–592.
Kaltsas GA, Isidori AM, Kola BP et al. The value of the low-dose dexamethasone suppression test in the differential diagnosis of hyperandrogenism in women. J Clin Endocrinol Metab 2003; 88:2634–2643.
Kendall JW, Sloop PR. Dexamethasone-suppressible adrenocortical tumor. N Engl J Med 1968; 279:532–535.
Caron P, Cogne M, Rumeau JL et al. Androgenic granulosa cell tumor of the ovary: in vivo hormonal studies. J Endocrinol Invest 1993; 16: 545–548.
Fiet J, Gueux B, Gourmelen M et al. Comparison of basal and adrenocorticotropinstimulated plasma 21-deoxycortisol and 17-hydroxyprogesterone values as biological markers of late-onset adrenal hyperplasia. J Clin Endocrinol Metab 1988; 66:659–667.
Pang S, Wang M, Jeffries S et al. Normal and elevated 3 alpha androstane diol glucuronide concentrations inwomenwith various causes of hirsutism and its correlation with degree of hirsutism and androgen levels. J Clin Endocrinol Metab 1992; 75:243–248.
Rittmaster RS, Zwicker H, Thompson Konok G, Norman RW. Androstanediol glucuronide production in human liver prostate and skin: evidence for the importance of the liver in 5 alpha reduced androgen metabolism. J Clin Endocrinol Metab 1993; 76:977–982.
Manieri C, Di Bisceglie C, Fornengo R et al. Postmenopausal virilization in a woman with gonadotropin dependent ovarian hyperthecosis. J Endocrinol Invest 1998; 21:128–132.
Deharo C, Berbis P, Privat Y. Complications dermatologiques des contraceptifs oraux. Fertil Contracept Sex 1988; 16:299–304.
McClamrock HD, Adashi EY. Gestational hyperandrogenism. Fertil Steril 1992; 57:257–274.
Morishima A, Grumbach MM, Simpson ER et al. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 1995; 80:3689–3698.
Ibanez L, Potau N, Virdis R et al. Postpubertal outcome in girls diagnosed of premature pubarche during childhood: increased frequency of functional ovarian hyperandrogenism. J Clin Endocrinol Metab 1993; 76:1599–1603.
Van Wayjen RG, Van den Ende A. Experience in the long-term treatment of patients with hirsutism and/or acne with cyproterone acetate-containing preparations: efficacy, metabolic and endocrine effects. Exp Clin Endocrinol Diabetes 1995; 103:241–251.
Jasonni VM, Bulletti C, Naldi S et al. Treatment of hirsutism by an association of oral cyproterone acetate and transdermal 17-betaestradiol. Fertil Steril 1991; 55:742–745.
Raudrant D, Rabe T. Progestogens with antiandrogenic properties. Drugs 2003; 63:463–492.
Ludicke F, Johanisson E, Helmerhorst FM et al. Effect of a combined oral contraceptive containing 3 mg of drospirenone and 30 μg of ethinyl-estradiol on the human endometrium. Fertil Steril 2001; 76:102–107.
Moghetti P, Tosi F, Tosti A et al. Comparison of spironolactone, flutamide and finasteride efficacy in the treatment of hirsutism: a randomized, double-blind placebo-controlled trial. J Clin Endocrinol Metab 2000; 85:89–94.
Carmina E, Lobo RA. Treatment of hyperandrogenic alopecia in women. Fertil Steril 2003; 79:91–95.
Jamin C. L’alopécie androgénogénétique. Ann Dermatol Venereol 2002; 129:801–803.
Vexiau P, Chaspoux C, Boudou P et al. Effects of minoxidil 2% vs cyproterone acetate treatment on female andrognetic alopecia: a controlled 12-month randomized trial. Br J Dermatol 2002; 146:992–999.
Carey AH, Chan KL, Short F et al. Evidence for a single gene effect causing polycystic ovaries and male pattern baldness. Clin Endocrinol (Oxf) 1993; 38:653–658.
Finasteride Male Pattern Hair Loss Study Group Long-term(5-year) multinational experience with finasteride 1 mg in the treatment of men with androgenetic alopecia. Eur J Dermatol 2002; 12:38–49.
Pierard-Franchimont C, Pierard GR. Postmenopausal aging of the sebaceous follicle: a comparison between women receiving hormone replacement therapy or not. Dermatology 2002; 204:17–22
Sator PG, Schmidt JB, Sator MO et al. The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas 2001; 39: 43–55.
Baulieu EE, Thomas G, Legrain S et al. Dehydroepiandrosterone (DHEA) DHEA sulfate and aging: contribution of the DHEAge study to a sociobiomedical issue. Proc Natl Acad Sci USA 2000; 97:4279–4284.
Fierens H, Delescluse J. Mélasma. In Thérapeutique dermatologique. Dubertret L, Aractingi S, Bachelez H, Bodemer C, Chosidow O, Cribier B, Joly P. Medecine-Sciences Flammarion, Paris, 2001, p. 535–538.
Herzberg AJ, Strohmeyer CR, Cirillo-Hyland VA. Autoimmune progesterone dermatitis. J Am Acad Dermatol 1995; 32:333–338.
Shelley WB, Shelley ED, Talanin NY, Santoso-Pham J. Estrogen dermatitis. J Am Acad Dermatol 1995; 32:25–31.
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Bennet, A., Vezzosi, D., Caron, P. (2012). Hormones sexuelles. In: Manifestations dermatologiques des maladies d’organes. Springer, Paris. https://doi.org/10.1007/978-2-287-72073-4_2
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