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Survie des patients atteints de cancer en France pp 355–361Cite as

Leucémie myéloïde chronique

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Abstrait

Comme les autres syndromes myéloprolifératifs,la leucémie myéloïde chronique (LMC)est un processus monoclonal résultant de l’atteinte d’une cellule souche. C ’est essentiellement la lignée granuleuse qui y prolifère. Elle est caractérisée par une aberration acquise du caryotype : la translocation (9 ;22)ou chromosome Philadelphie (Ph1), se traduisant par la juxtaposition anormale des gènes abl du chromosome 9 et bcr du chromosome 22 (1).Il s ’agit du premier exemple de signature chromosomique et moléculaire mis en évidence parmi les cancers humains.

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Références

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Authors
  1. P. M. Carli
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  2. X. Troussard
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  3. N. Maarouf
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  4. M. Maynadié
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Editor information

Editors and Affiliations

  1. Registre des cancers du Tarn, BP 37, 81001, Albi Cedex

    Pascale Grosclaude

  2. Service de biostatistique des Hospices civils de Lyon UMR 5558, Centre hospitalier Lyon Sud, 69495, Pierre-Benite Cedex

    Jacques Estève , Nadine Bossard , Laurent Remontet  & Aurélien Belot , ,  & 

  3. Registre bourguignon des cancers digestifs, Faculté de médecine, 7, boulevard Jeanne d’Arc, BP 87900, 21033, Dijon Cedex

    Jean Faivre  & Anne-Marie Bouvier  & 

  4. Registre digestif du Calvados, CHRU Côte de Nacre UFR de médecine, Avenue de Côte de Nacre, 14032, Caen Cedex

    Guy Launoy

  5. Registre des cancers du Bas-Rhin Laboratoire d’épidémiologie et de santé publique, Faculté de médecine, 11, rue Humann, 67085, Strasbourg Cedex

    Michel Velten

  6. Registre hématologique de Côte d’Or, Faculté de médecine, 7, boulevard Jeanne d’Arc, 21033, Dijon Cedex

    Marc Maynadié

  7. Registre gynécologique de Côte d’Or, Centre G.-F. Leclerc, 1, rue Professeur Marion, BP 77980, 21079, Dijon Cedex

    Patrick Arveux

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© 2007 Springer-Verlag France

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Carli, P.M., Troussard, X., Maarouf, N., Maynadié, M. (2007). Leucémie myéloïde chronique. In: Grosclaude, P., et al. Survie des patients atteints de cancer en France. Springer, Paris. https://doi.org/10.1007/978-2-287-39310-5_46

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  • DOI: https://doi.org/10.1007/978-2-287-39310-5_46

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-39305-1

  • Online ISBN: 978-2-287-39310-5

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