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Heart Histopathology in Ischemia-Reperfusion Injury

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Book cover Principles of Pulmonary Protection in Heart Surgery

Abstract

Ischemic necrosis of a group of cells – infarct – develops if the blood flow is discontinued. The type of circulation of an organ influences the way such cell death occurs. Organs with double circulation, like lungs and bowel, usually resist the closure of one arterial channel, provided the other one is open. Thus, infarcts of these organs occur only when both territories are affected, most frequently due to a global circulatory collapse secondary to heart failure or shock. Anyway, these infarctions are commonly hemorrhagic. The heart has a single circulation with poor collateral branching. Thus, the closure at one point of the arterial tree is enough to cause myocardial infarct, which is usually anemic (“white” infarct).

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Correspondence to Paulo Sampaio Gutierrez .

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Gutierrez, P.S., Ishigai, M.M.d.S. (2010). Heart Histopathology in Ischemia-Reperfusion Injury. In: Gabriel, E., Salerno, T. (eds) Principles of Pulmonary Protection in Heart Surgery. Springer, London. https://doi.org/10.1007/978-1-84996-308-4_14

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  • DOI: https://doi.org/10.1007/978-1-84996-308-4_14

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